Impact of cow milk production on cow–calf performance in the Nebraska Sandhills

Livestock producers have tended to select for increased output traits like milk production and growth to increase productivity. Even with the increased selection for greater calf growth potential, some regions in the United States have seen a plateau in calf body weight (BW) at weaning (Lalman et al., 2019). When focusing on reaching maximum potential of these output traits, it is important to consider the multitude of variables that affect a production system. With increased milk production, nutrient requirements for cows become increased (Ferrell and Jenkins, 1984; Montaño-Bermudez et al., 1990), which may not be met if range and forage availability for grazing is already limited at meeting lactation demands. Historically, weaning weight and milk production have been associated with a positive relationship with greater milk production resulting in heavier calves at weaning (Clutter and Nielsen, 1987; Abdelsamei et al., 2005). In contrast, others have only observed the benefit of increased milk production improving calf performance within the first 60 d after birth (Clutter and Nielsen, 1987; Ansotegui et al, 1991; Edwards et al., 2017). Gleddie and Berg (1968) reported the correlation between average daily gain (ADG) of calves and milk yield estimates increased between the first and second month and continued to decrease thereafter as the forage consumption increased. The reliance on milk for dietary energy can result in increased calf BW at peak lactation (Edwards et al., 2017), but benefits of increased milk production may decrease as stage of lactation increases. Our hypothesis was that increasing milk production would negatively affect cow reproductive performance while having no effect on calf performance. Therefore, the objective of this study was to determine the impact milk production has on subsequent cow reproductive performance and calf performance throughout the preweaning and postweaning phases

Impact of cow milk production on cow–calf performance in the Nebraska Sandhills

Livestock producers have tended to select for increased output traits like milk production and growth to increase productivity. Even with the increased selection for greater calf growth potential, some regions in the United States have seen a plateau in calf body weight (BW) at weaning (Lalman et al., 2019). When focusing on reaching maximum potential of these output traits, it is important to consider the multitude of variables that affect a production system. With increased milk production, nutrient requirements for cows become increased (Ferrell and Jenkins, 1984; Montaño-Bermudez et al., 1990), which may not be met if range and forage availability for grazing is already limited at meeting lactation demands. Historically, weaning weight and milk production have been associated with a positive relationship with greater milk production resulting in heavier calves at weaning (Clutter and Nielsen, 1987; Abdelsamei et al., 2005). In contrast, others have only observed the benefit of increased milk production improving calf performance within the first 60 d after birth (Clutter and Nielsen, 1987; Ansotegui et al, 1991; Edwards et al., 2017). Gleddie and Berg (1968) reported the correlation between average daily gain (ADG) of calves and milk yield estimates increased between the first and second month and continued to decrease thereafter as the forage consumption increased. The reliance on milk for dietary energy can result in increased calf BW at peak lactation (Edwards et al., 2017), but benefits of increased milk production may decrease as stage of lactation increases. Our hypothesis was that increasing milk production would negatively affect cow reproductive performance while having no effect on calf performance. Therefore, the objective of this study was to determine the impact milk production has on subsequent cow reproductive performance and calf performance throughout the preweaning and postweaning phases

Effect of Supplemental Protein and Glucogenic Precursors on Digestibility and Energy Metabolism

A metabolism study was conducted to evaluate the impact of increasing levels of glucogenic precursors on diet digestibility and acetate clearance. Four supplementation strategies containing 0, 30, 40, and 70 g of supplemental glucogenic potential were supplied to a basal diet of bromegrass hay. Addition of glucogenic potential in the form of rumen undegradable protein improved dry matter, organic matter, and acid detergent fiber digestibility efficiency of acetate utilization in growing lambs fed moderate- quality hay. However, no additive effect of supplementing propionate salts and rumen undegradable protein were observed in this study. Th is would suggest that rumen undegradable protein requirements must be met to observe effects from increasing levels of glucogenic potential

Effect of Glucogenic Feed Additive on Reproductive Performance in Young Postpartum Range Cows

Performance of young March-Calving range cows receiving a protein supplement with the addition of either monensin or propionate salt were compared to evaluate the effect of feed additive on overall production in the postpartum stage. cow body weight and body condition were not impacted by postpartum supplementation throughout the study. Calf body weights were not impacted by type of feed additive at birth, weaning, or 205-d. Twenty-four-hour milk production was not impacted by the type of feed additive. Conception rates for cows receiving postpartum supplementation containing propionate salt were greater than cows receiving monsensin. This implies that the addition of propionate salt when supplementing young range cows in the postpartum period can increase pregnancy rate resulting in an increase in marginal revenue compared to cows fed monensin

Effects of Isolated Nutrients in Distillers Grains on Total Tract Digestibility and Digestible Energy in Forage Diets

A digestion study was conducted to evaluate the contribution of individual nutrient components of distillers grains on nutrient digestibility and digestible energy. All diets contained 56% brome hay with a control diet containing either 40% corn; or 40% modified distillers grains. Four additional diets compared the contribution of fat, protein, fiber, and solubles components of distillers grains. No differences were observed for digestibility of DM, OM, and NDF among treatments. Feeding the isolated protein resulted in similar digestible energy to modified distillers grains, suggesting the bypass protein component contributes heavily to energy in distillers

Effect of Harvest Method on Digestibility of Corn Residue

Corn residues can be an economical forage source for producers and advanced harvest methods have increased the quality of baled residue. A digestion study was conducted to evaluate the effects of harvest method of corn residues (low- stem, highstem, and conventional) on digestibility in lambs. Samples from total fecal collection were dried 1 of 3 ways to determine effects on digestibility estimates. Corn residue containing low- stem had greatest overall digestibility with high- stem residue being intermediate and conventional harvesting having the lowest digestibility. Drying method had no effect on digestibility estimates

Effect of harvest method and ammoniation of baled corn residue on intake and digestibility in lambs

To determine the effect of harvest method and ammoniation on both in vivo and in vitro digestibility of corn residue, six corn residue treatments consisting of three different harvest methods either with or without anhydrous ammonia chemical treatment (5.5% of dry matter [DM]) were evaluated. The harvest methods included conventional rake-and-bale (CONV) and New Holland Cornrower with eight rows (8ROW) or two rows (2ROW) of corn stalks chopped into the windrow containing the tailings (leaf, husk, and upper stem) from eight rows of harvested corn (ammoniated bales of each harvest method resulted in treatments COVAM, 8RAM, and 2RAM). Nine crossbred wether lambs (49.2 ± 0.5 kg BW) were fed 64.2% corn residue, 29.8% wet corn gluten feed, 3.3% smooth-bromegrass hay, and 2.8% mineral mix (DM basis) in a 9 × 6 Latin rectangle metabolism study with a 3 × 2 factorial treatment to measure total tract disappearance. Six 21-d periods consisted of 14-d adaptation and 7-d total fecal collection, and lambs were fed ad libitum (110% of the previous day’s DM intake [DMI]) during days 1 to 12 and reduced to 95% of ad libitum intake for days 13 to 21. There was a harvest method by ammoniation interaction (P \u3c 0.01) for ad libitum DMI (days 7 to 11). Ammoniation increased (P \u3c 0.01) intake across all harvest methods, where 2RAM DMI was 4.1%, COVAM was 3.6%, and 8RAM was 3.1%, which were all different (P \u3c 0.01) from each other, but all untreated residues were consumed at 2.6% of BW (P ≥ 0.92) regardless of harvest method. There were no interactions (P \u3e 0.34) between harvest method and ammoniation for any total tract or in vitro digestibility estimate. Harvest method affected (P \u3c 0.04) DM, neutral detergent fiber (NDF), and acid detergent fiber (ADF) digestibility, where 2ROW was greater than both CONV and 8ROW, which did not differ. The organic matter (OM) digestibility (P = 0.12) and digestible energy (DE; P = 0.30) followed the same numerical trend. Both in vitro DM digestibility (IVDMD) and in vitro OM digestibility (IVOMD) of the residue were affected (P \u3c 0.01) by harvest method, with 2ROW being greater (P \u3c 0.01) than both CONV and 8ROW. For IVDMD, 8ROW was not (P = 0.77) different from CONV, but 8ROW IVOMD was lower (P = 0.03) than CONV. Ammoniation improved (P \u3c 0.01) DM, OM, NDF, and ADF digestibility of all harvest methods, resulting in a 26% increase (P \u3c 0.01) in DE due to ammoniation. Similar digestibility improvements were observed in vitro with ammoniation improving IVDMD and IVOMD by 23% and 20%, respectively. Both selective harvest methods and ammoniation can improve the feeding value of baled corn residue

Effect of Harvest Method and Ammoniation on Digestibility and Intake of Corn Residue

The effects of three harvest methods, both with and without ammonia treatment, on the in vivo digestibility and intake of baled corn residue were assessed in a digestion trial with lambs. Treatments included three corn residue harvest methods (conventional rake and bale, New Holland Cornrower™ with eight rows or with two rows of corn stalks chopped into the windrow containing the tailings [leaf, husk and upper stalk] from eight harvested rows) and the effects of ammoniation at 5.5% of DM compared to no ammoniation of the residue. Th e 2- Row baled residue (51.7%) had greater dry matter digestibility than both 8- Row (47.3%) and CONV (44.7%). Ammoniation increased dry matter digestibility by 24% (10 percentage units) across all residue types. Additionally, ammoniation increased intake. Utilizing alternative harvesting technologies and ammoniation can improve the digestibility of baled residue. These effects are additive and combining the two technologies resulted in the greatest improvement in digestibility

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

Significance Contributions of rare variants to common and complex traits such as type 2 diabetes (T2D) are difficult to measure. This paper describes our results from deep whole-genome analysis of large Mexican-American pedigrees to understand the role of rare-sequence variations in T2D and related traits through enriched allele counts in pedigrees. Our study design was well-powered to detect association of rare variants if rare variants with large effects collectively accounted for large portions of risk variability, but our results did not identify such variants in this sample. We further quantified the contributions of common and rare variants in gene expression profiles and concluded that rare expression quantitative trait loci explain a substantive, but minor, portion of expression heritability.</jats:p