3,100 research outputs found

    Liquid oil painting: Free and forced convection in an enclosure with mechanical and thermal forcing

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    A fluid dynamics video is linked to this article, which have been submitted to the Gallery of Fluid Motion as part of the 65th American Physical Society meeting of the Division of Fluid Dynamics, held in San Diego, California, USA, over 17-20 November 2012. The video serves to visualize flows generated in a rectangular enclosure that are subjected to both mechanical and thermal forcing through a common horizontal boundary. This system exhibits features consistent with either horizontal convection or lid-driven cavity flows depending on the ratio between thermal and mechanical stirring, and three different cases are visualized in the linked videos.Comment: 2 video files attached, 4 pages, 1 figure. This article is submitted accompanying a video submitted to the Gallery of Fluid Motion as part of the 65th Division of Fluid Dynamics meeting of the American Physical Society (17-20 November, San Diego, CA, USA

    Second-order structure function analysis of scatterometer winds over the Tropical Pacific

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    22 pages, 16 figures, 1 tableKolmogorov second-order structure functions are used to quantify and compare the small-scale information contained in near-surface ocean wind products derived from measurements by ASCAT on MetOp-A and SeaWinds on QuikSCAT. Two ASCAT and three SeaWinds products are compared in nine regions (classified as rainy or dry) in the tropical Pacific between 10°S and 10°N and 140° and 260°E for the period November 2008 to October 2009. Monthly and regionally averaged longitudinal and transverse structure functions are calculated using along-track samples. To ease the analysis, the following quantities were estimated for the scale range 50 to 300 km and used to intercompare the wind products: (i) structure function slopes, (ii) turbulent kinetic energies (TKE), and (iii) vorticity-to-divergence ratios. All wind products are in good qualitative agreement, but also have important differences. Structure function slopes and TKE differ per wind product, but also show a common variation over time and space. Independent of wind product, longitudinal slopes decrease when sea surface temperature exceeds the threshold for onset of deep convection (about 28°C). In rainy areas and in dry regions during rainy periods, ASCAT has larger divergent TKE than SeaWinds, while SeaWinds has larger vortical TKE than ASCAT. Differences between SeaWinds and ASCAT vortical TKE and vorticity-to-divergence ratios for the convectively active months of each region are large. © 2014. American Geophysical Union. All Rights ReservedThe ASCAT-12.5 and ASCAT-25 data used in this work can be ordered online from the EUMETSAT Data Centre (www.eumetsat.int) as SAF type data in BUFR or NetCDF format. They can also be ordered from PO.DAAC (podaac.jpl.nasa.gov) in NetCDF format only. The SeaWinds-NOAA and QuikSCAT-12.5 data are also available from PO.DAAC. The SeaWinds-KNMI data are available from the KNMI archive upon an email request to [email protected]. Rain-rates and sea surface temperatures were obtained from the Tropical Rainfall Measuring Mission's (TRMM) Microwave Imager (TMI) archive at the Remote Sensing Systems web site (www.ssmi.com). SeaWinds Radiometer (SRAD) rain-rates were obtained from the QuikSCAT 25 km L2B science data product that is available from PO.DAAC. This work has been funded by EUMETSAT in the context of the Numerical Weather Prediction Satellite Applications Facility (NWP SAF). The contribution of GPK has been supported by EUMETSAT as part of the SAF Visiting Scientists programmePeer Reviewe

    Dynamic Customer Acquisition and Retention Management

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134194/1/poms12559.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134194/2/poms12559_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134194/3/poms12559-sup-0001-Appendix.pd

    Developing and Supporting the Future Extension Professional

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    Continual disruption and change describe the new normal. Embedded in complex systems and cultures, Extension professionals are at the heart of this change for many of today\u27s issues. Relying on the traditional models for developing Extension professionals will not be enough for Extension to make a significant impact in the future. We present a model of education and training to develop and support Extension professionals as they work with individuals, organizations, and communities in the 21st century

    Tubular carbonate concretions as hydrocarbon migration pathways? Examples from North Island, New Zealand

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    Cold seep carbonate deposits are associated with the development on the sea floor of distinctive chemosyn¬thetic animal communities and carbonate minerali¬sation as a consequence of microbially mediated anaerobic oxidation of methane. Several possible sources of the methane exist, identifiable from the carbon isotope values of the carbonate precipitates. In the modern, seep carbonates can occur on the sea floor above petroleum reservoirs where an important origin can be from ascending thermogenic hydrocar¬bons. The character of geological structures marking the ascent pathways from deep in the subsurface to shallow subsurface levels are poorly understood, but one such structure resulting from focused fluid flow may be tubular carbonate concretions. Several mudrock-dominated Cenozoic (especially Miocene) sedimentary formations in the North Island of New Zealand include carbonate concretions having a wide range of tubular morphologies. The concretions are typically oriented at high angles to bedding, and often have a central conduit that is either empty or filled with late stage cements. Stable isotope analyses (δ13C, δ18O) suggest that the carbonate cements in the concretions precipitated mainly from ascending methane, likely sourced from a mixture of deep thermogenic and shallow biogenic sources. A clear link between the tubular concretions and overlying paleo-sea floor seep-carbonate deposits exists at some sites. We suggest that the tubular carbonate concretions mark the subsurface plumbing network of cold seep systems. When exposed and accessible in outcrop, they afford an opportunity to investigate the geochemical evolution of cold seeps, and possibly also the nature of linkages between subsurface and surface portions of such a system. Seep field development has implications for the characterisation of fluid flow in sedimentary basins, for the global carbon cycle, for exerting a biogeochemical influence on the development of marine communities, and for the evaluation of future hydrocarbon resources, recovery, and drilling and production hazards. These matters remain to be fully assessed within a petroleum systems framework for New Zealand’s Cenozoic sedimentary basins

    Measurements and calculations of the Coulomb cross section for the production of direct electron pairs by energetic heavy nuclei in nuclear track emulsion

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    Measurements and theoretical predictions of the Coulomb cross section for the production of direct electron pairs by heavy ions in emulsion have been performed. Nuclear track emulsions were exposed to the 1.8 GeV/amu Fe-56 beam at the Lawrence Berkeley Laboratory bevalac and to the 60 and 200 GeV/amu O-16 and the 200 GeV/amu S-32 beam at the European Center for Nuclear Research Super Proton Synchrotron modified to accelerate heavy ions. The calculations combine the Weizsacker-Williams virtual quanta method applicable to the low-energy transfers and the Kelner-Kotov relativistic treatment for the high-energy transfers. Comparison of the measured total electron pair yield, the energy transfer distribution, and the emission angle distribution with theoretical predictions revealed a discrepancy in the frequency of occurrence of the low-energy pairs (less than or = 10 MeV). The microscope scanning criteria used to identify the direct electron pairs is described and efforts to improve the calculation of the cross section for pair production are also discussed

    Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease

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    Prion diseases are fatal, transmissible, neurodegenerative diseases caused by the misfolding of the prion protein (PrP). At present, the molecular pathways underlying prion-mediated neurotoxicity are largely unknown. We hypothesized that the transcriptional regulator of the stress response, heat shock factor 1 (HSF1), would play an important role in prion disease. Uninoculated HSF1 knockout (KO) mice used in our study do not show signs of neurodegeneration as assessed by survival, motor performance, or histopathology. When inoculated with Rocky Mountain Laboratory (RML) prions HSF1 KO mice had a dramatically shortened lifespan, succumbing to disease ≈20% faster than controls. Surprisingly, both the onset of home-cage behavioral symptoms and pathological alterations occurred at a similar time in HSF1 KO and control mice. The accumulation of proteinase K (PK)-resistant PrP also occurred with similar kinetics and prion infectivity accrued at an equal or slower rate. Thus, HSF1 provides an important protective function that is specifically manifest after the onset of behavioral symptoms of prion disease

    New calculations and measurements of the Coulomb cross-section for the production of direct electron pairs by high energy nuclei

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    Recently, new calculations were made of the direct Coulomb pair cross section that rely less in arbitrary parameters. More accurate calculations of the cross section down to low pair energies were made. New measurements of the total direct electron pair yield, and the energy and angular distribution of the electron pairs in emulsion were made for O-16 at 60 and 200 GeV/amu at S-32 at 200 GeV/amu which give satisfactory agreement with the new calculations. These calculations and measurements are presented along with previous accelerator measurements made of this effect during the last 40 years. The microscope scanning criteria used to identify the direct electron pairs is described. Prospects for application of the pair method to cosmic ray energy measurements in the region 10 (exp 13) to 10 (exp 15) eV/amu are discussed

    A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia

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    Intraflagellar transport (IFT), which is essential for the formation and function of cilia in most organisms, is the trafficking of IFT trains (i.e. assemblies of IFT particles) that carry cargo within the cilium. Defects in IFT cause several human diseases. IFT trains contain the complexes IFT-A and IFT-B. To dissect the functions of these complexes, we studied a Chlamydomonas mutant that is null for the IFT-A protein IFT140. The mutation had no effect on IFT-B but destabilized IFT-A, preventing flagella assembly. Therefore, IFT-A assembly requires IFT140. Truncated IFT140, which lacks the N-terminal WD repeats of the protein, partially rescued IFT and supported formation of half-length flagella that contained normal levels of IFT-B but greatly reduced amounts of IFT-A. The axonemes of these flagella had normal ultrastructure and, as investigated by SDS-PAGE, normal composition. However, composition of the flagellar \u27membrane+matrix\u27 was abnormal. Analysis of the latter fraction by mass spectrometry revealed decreases in small GTPases, lipid-anchored proteins and cell signaling proteins. Thus, IFT-A is specialized for the import of membrane-associated proteins. Abnormal levels of the latter are likely to account for the multiple phenotypes of patients with defects in IFT140. This article has an associated First Person interview with the first author of the paper
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