33 research outputs found

    A Nation-Wide Planning Framework for Large-Scale Collaboration on Legacy Print Monograph Collections

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    Libraries are working toward collaborative management and preservation of print journals, newspapers, legal materials, and government documents; they must also establish a similar concerted effort focused on print monographs. Monographs present complex challenges at a time when libraries want to ensure the preservation of the print record but have increasing incentives to divest of older, less used print materials and take advantage of the affordances of electronic text. With LYRASIS as lead organization, planning partners California Digital Library (CDL), Committee on Institutional Cooperation (CIC), and Center for Research Libraries (CRL)were awarded a grant from the Institute for Museum and Library Services (IMLS) to conduct a workshop titled “Developing a North-American Strategy to Preserve & Manage Print Collections of Monographs.” Workshop participants discussed the challenges and issues involved in collaborative monograph preservation and formulated an agenda of research and demonstration projects to test elements of a strategy

    Regional and National Cooperation on Legacy Print Collections

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    This reports on a meeting convened by the Center for Research Libraries on July 10, 2009, in Chicago for representatives of more than a dozen library consortia and other organizations with an interest in shaping a national approach to long-term preservation of and access to print collections

    A distributed national stored collection: Testing the possibilities

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    This paper reports on a study of the holdings of a single discipline (Design) by a single institution (RMIT University Library) in order to test for the possibility of a form of distributed national storage in Australia. The study was undertaken using OCLC Collection Analysis software and the WorldCat database. The collection of RMIT University Library is compared with two ‘groups’ of libraries, the first consisting of seven Victorian academic library collections, and the second of three Melbourne-based non-academic libraries considered to have strong Design collections. Conclusions indicate that for this discipline a form of distributed storage is already in place, with the RMIT University Library collection making a considerable and complementary contribution to the state wide holdings

    HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation.

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    The internal ribosome entry site (IRES) of the hepatitis C virus (HCV) drives noncanonical initiation of protein synthesis necessary for viral replication. Functional studies of the HCV IRES have focused on 80S ribosome formation but have not explored its role after the 80S ribosome is poised at the start codon. Here, we report that mutations of an IRES domain that docks in the 40S subunit's decoding groove cause only a local perturbation in IRES structure and result in conformational changes in the IRES-rabbit 40S subunit complex. Functionally, the mutations decrease IRES activity by inhibiting the first ribosomal translocation event, and modeling results suggest that this effect occurs through an interaction with a single ribosomal protein. The ability of the HCV IRES to manipulate the ribosome provides insight into how the ribosome's structure and function can be altered by bound RNAs, including those derived from cellular invaders

    The ATLAS Data Acquisition and High-Level Trigger: Concept, Design and Status

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    The Trigger and Data Acquisition system (TDAQ) of the ATLAS experiment at the CERN Large Hadron Collider is based on a multi-level selection process and a hierarchical acquisition tree. The system, consisting of a combination of custom electronics and commercial products from the computing and telecommunication industry, is required to provide an online selection power of 105 and a total throughput in the range of Terabit/sec. This paper introduces the basic system requirements and concepts, describes the architecture of the system, discusses the basic measurements supporting the validity of the design and reports on the actual status of construction and installation

    The ATLAS trigger - high-level trigger commissioning and operation during early data taking

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    The ATLAS experiment is one of the two general-purpose experiments due to start operation soon at the Large Hadron Collider (LHC). The LHC will collide protons at a centre of mass energy of 14~TeV, with a bunch-crossing rate of 40~MHz. The ATLAS three-level trigger will reduce this input rate to match the foreseen offline storage capability of 100-200~Hz. This paper gives an overview of the ATLAS High Level Trigger focusing on the system design and its innovative features. We then present the ATLAS trigger strategy for the initial phase of LHC exploitation. Finally, we report on the valuable experience acquired through in-situ commissioning of the system where simulated events were used to exercise the trigger chain. In particular we show critical quantities such as event processing times, measured in a large-scale HLT farm using a complex trigger menu

    Performance of the final Event Builder for the ATLAS Experiment

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    Event data from proton-proton collisions at the LHC will be selected by the ATLAS experiment in a three level trigger system, which reduces the initial bunch crossing rate of 40 MHz at its first two trigger levels (LVL1+LVL2) to ~3 kHz. At this rate the Event-Builder collects the data from all Read-Out system PCs (ROSs) and provides fully assembled events to the the Event-Filter (EF), which is the third level trigger, to achieve a further rate reduction to ~200 Hz for permanent storage. The Event-Builder is based on a farm of O(100) PCs, interconnected via Gigabit Ethernet to O(150) ROSs. These PCs run Linux and multi-threaded software applications implemented in C++. All the ROSs and one third of the Event-Builder PCs are already installed and commissioned. We report on performance tests on this initial system, which show promising results to reach the final data throughput required for the ATLAS experiment

    Reference and Information Services (Book Review)

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    Bibliographic Instruction in Practice; What is Good Instruction Now?; Working With Faculty in the New Electronic Library (Book Review)

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