257 research outputs found

    Physical Multi-Layer Phantoms for Intra-Body Communications

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    This paper presents approaches to creating tissue mimicking materials that can be used as phantoms for evaluating the performance of Body Area Networks (BAN). The main goal of the paper is to describe a methodology to create a repeatable experimental BAN platform that can be customized depending on the BAN scenario under test. Comparisons between different material compositions and percentages are shown, along with the resulting electrical properties of each mixture over the frequency range of interest for intra-body communications; 100 KHz to 100 MHz. Test results on a composite multi-layer sample are presented confirming the efficacy of the proposed methodology. To date, this is the first paper that provides guidance on how to decide on concentration levels of ingredients, depending on the exact frequency range of operation, and the desired matched electrical characteristics (conductivity vs. permittivity), to create multi-layer phantoms for intra-body communication applications

    Retrieving planet formation parameters of WASP-77Ab using SimAb

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    Context. The atmospheric compositions of planets offer a unique view into their respective formation processes. State-of-the-art observatories and techniques are finally able to provide high-precision data on atmospheric composition that can be used to constrain planet formation. Aims. In this context, we focus on the formation of WASP-77Ab based on previous observations of its atmosphere, which have provided precise C/O and metallicity measurements. Methods. We use the SimAb planet formation simulation to model the formation of WASP-77Ab. We assume two compositions for the disk WASP-77Ab was formed within: one of a solar composition and one that represents the composition of WASP-77A. In addition, we consider two different scenarios regarding the migration of the planet and we study the possible planet formation paths that reproduce the composition of WASP-77Ab. Result. This work shows that the planet is expected to have formed in a disk where not many planetesimals could be accreted. Moreover, we demonstrate that the most likely migration scenario is disk-free migration, whereby the planet initiates its Type II migration within the CO ice line and ends it beyond the water ice line

    Data Acquisition and Processing of Hartha Formation in the east Baghdad oil field, Central of Iraq

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    A three-dimensional survey was carried out to Eastern Baghdad oil field, which consist three parts, the area of (EB South- 2 ) approximately 179,875 km2 and ( EB South-1) is about (602.03) km2, while the space segment (EB South-3) is approximately to (419.095) km2. In this research, was focused on Hartha Formation only. Based on many tests to designation of pre-planning of the survey to get good signal to noise ratio for receivers in addition to the best suit for vibrators distribution and also getting the best signal source where spread of a 60-line impact and the distance between the point of receive and the other are (2 meters), also using (5) vibrators Type (NOMAD 65) with a maximum capacity of (62000 LB) for each shock. Where all processes work such as enhancing signal at the expense of noise, correction CDP gather for Normal Move Out (NMO) and stack them, correction for influence of near-surface time delays (static correction), filtering processes, providing velocity information, increasing resolution and collapsing diffractions and placing dipping events in their correct subsurface locations (migration) This processes are achieved using computers, they include many mathematical processes depend on physical fundamentals. The main processes in seismic data processing include : stacking, deconvolution, and migration. By using the information of EB-1 Well, and making the relationship time-depth curve of EB-1 then following up on getting synthetic to be linked later with seismic data and sections to obtain a real subsurface image

    EFFICACY AND SAFETY OF CLADRIBINE: SUBCUTANEOUS VERSUS INTRAVENOUS ADMINISTRATION IN HAIRY CELL LEUKEMIA PATIENTS

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    Cladribine induces durable complete remission (CR) in approximately 85% of hairy cell leukemia (HCL) patients. In Egypt, cladribine is mainly used as IV continuous infusion at a dose of 0.1 mg/kg/day for 7 days and as SC bolus injection at a dose of 0.14 mg/kg/day for 5 days. We aimed to compare the outcome and toxicity between these two regimens. We retrospectively collected data of HCL patients treated at the National Cancer Institute and its affiliated center, Nasser Institute, Cairo, Egypt. Forty nine patients were identified, 18 treated with the IV regimen (IV group) and 31 with the SC regimen (SC group). Forty-one patients were newly diagnosed. Patient characteristics were balanced across the two groups. The CR rates in the IV and the SC group were 94% and 97%, respectively. The main complications in the IV group and the SC were neutropenia G3-4 (67% vs 87%), mucositis mainly G1-2 (67% vs 32%) and infections (mainly viral, 78% vs 34%). In the IV group, 5 patients died, 3 of progression and infection, one of unknown cause and one of late heart failure. In the SC group, one patient died of disease progression and one of second cancer. After 33.5 months median follow up, the 3-year event free survival was 60% and 96%, respectively (p=0.104). The 3-year overall survival was 81% and 100%, respectively (p=0.277). Lymphadenopathy and/or hepatomegaly may have negative influence on DFS. In conclusion, SC cladribine is an excellent alternative to the IV regimen for the treatment of HCL.  Key words: 2-chlorodeoxyadenosine, cladribine, hairy cell leukemia, intravenous, subcutaneou

    3D Reservoir Study for Yamama Formation in Nasirya Oil field in Southern of Iraq

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    Nasriya oil field is located at the Southern part of Iraq, this field is a giant and prolific, so it take a special are from the Oil Exploration Company for development purposes by using 3D seismic reflection. The primary objective of this thesis is to obtain reservoir properties and enhance the method of getting precise information about subsurface reservoir characterizations by improving the estimation of petrophysical properties (effective porosity, P-wave, water saturation and poisson's ratio). There are five wells in the study area penetrated the required reservoirs within Yammam Formation. The Synthetic seismogram of Nasriya wells were created to conduct well tie with seismic data. These well tie was very good matching with seismic section using best average statistical wavelet. Five main horizons were picked from the reflectors by using synthetic seismogram for wells then converted to structural maps in depth domain by using average velocity of five wells. By using petrel program TWT maps have been constructed from the picked horizons, Average velocity maps calculated from the wells velocities survey data and the sonic log information and Depth maps construction was drawn using Direct time-depth conversion and the general trend of these map was NW-SE. The model of low frequency was created from the low frequency contents from well data and the five main horizons were picked. The seismic inversion technique was performed on post-stack three dimensions (3D) seismic data in Nasriya oil field

    Evaluation of acute and sub-chronic toxicity of Semelil (ANGIPARS�), a new phytotherapeutic drug for wound healing in rodents

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    Semelil (ANGIPARS�), an herbal formulation containing Melilotus officinalis extract, is a novel compound being developed for treatment of chronic wounds, particularly diabetic foot ulcers. The purpose of this study was to investigate toxicological, pharmacological, and pathomorphological effects of I.M. and I.P. administration of Semelil in animals. The acute toxicity parameters of Semelil diluted in normal saline (1:10 or 1:5) were determined after a single injection into BALB/c mice and Wistar rats in two steps. First, the LD50 was approximately assessed and then the precise lethal dose indices were estimated by the probit-analysis method. Specific single-dose effects of Semelil were monitored for clinical signs of toxicity, including general state of the animals, changes in their behavior, hematological and biochemical parameters for 14 days after drug administration. Then, subacute-chronic toxicity was evaluated in rats treated with Semelil for 3 months. In acute toxicity study, the calculated LD50 for drug diluted at 1:5 was in the range of 44-52 ml/kg. The adverse effects at drug doses close to the LD50 included depressed mood, narcosis, and sleep. No adverse pharmacological or toxicological effects of the drug diluted at 1:10 and administered in the single-dose (25-50 ml/kg body wt.) or chronically (daily doses of 0.07 and 0.21 ml/kg body wt.) were noted. Thus, the animal studies demonstrated a favorable safety profile for the phytotherapeutic Semelil

    The effect of Setarud (IMOD�) on angiogenesis in transplanted human ovarian tissue to nude mice

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    Background: One of the promising methods in fertility preservation among women with cancer is cryopreservation of ovarian cortex but there are many drawbacks such as apoptosis and considerable reduction of follicular density in the transplanted ovary. One solution to reduce ischemic damage is enhancing angiogenesis after transplantation of ovarian cortex tissue. Objective: The aim of this study was to investigate the effect of Setarud, on angiogenesis in transplanted human ovarian tissue. Materials and Methods: In this case control study, twenty four nude mice were implanted subcutaneously, with human ovarian tissues, from four women. The mice were randomly divided into two groups (n=12): the experimental group was treated with Setarud, while control group received only vehicle. Each group was divided into three subgroups (n=4) based on the graft recovery days post transplantation (PT). The transplanted fragments were removed on days 2, 7, and 30 PT and the expression of Angiopoietin-1, Angiopoietin-2, and Vascular endothelial growth factor at both gene and protein levels and vascular density were studied in the grafted ovarian tissues. Results: On the 2nd and 7th day PT, the level of Angiopoietin-1 gene expression in case group was significantly lower than that in control group, while the opposite results were obtained for Angiopoietin-2 and Vascular endothelial growth factor. These results were also confirmed at the protein level. The density of vessels in Setarud group elevated significantly on day 7 PT compared to pre-treatment state. Conclusion: Our results showed that administration of Setarud may stimulates angiogenesis in transplanted human ovarian tissues, although further researches are needed before a clear judgment is made. � 2015, Research and Clinical Center for Infertitlity. All rights reserved
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