Comparison of two brands of methylphenidate (Stimdate® vs. Ritalin®) in children and adolescents with attention deficit hyperactivity disorder: A double-blind, randomized clinical trial

Objective: To compare the effectiveness and safety of the methylphenidate produced in Iran (Stimdate®) with its original brand (Ritalin®) in children with Attention deficit hyperactivity disorder (ADHD). Methods: In this double-blinded randomized clinical trial, 30 patients with ADHD who were 6 to 16 years old, were divided into two groups: 15 in Stimdate® and 15 in Ritalin® group. The two groups were compared for side effects profile, Conner's Parent's Rating Scale-Persion version (CPRS-R), Child Symptom Inventory-4 (CSI-4), Clinical Global Impressions (CGI), and Children's Global Assessment Scale (CGAS), at baseline and at the 4 th and 6 th weeks. Results: The subjects showed significant decreases in the CPRS-Rand CSI-4 scores and significant increase of CGAS scores during the follow-up, but there were no significant difference between Stimdate® and Ritalin® group, regarding the pattern of changes observed. The mean therapeutic dose and the number of side effects were not significantly different between the two studied groups. Conclusions: Both Stimdate® and Ritalin® had comparable clinical efficacy and safety in children with ADHD

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers

https://deepblue.lib.umich.edu/bitstream/2027.42/138963/1/12987_2017_Article_71.pd

Cellular internalization of Bortezomib loaded CS MNPs by cervical cancer cells

FEBS EMBO 2014 Conference -- AUG 30-SEP 04, 2014 -- Paris, FRANCEWOS: 000359666803040…FEBS, EMB

Loading and release efficiencies of Bortezomib on chitosan coated magnetic nanoparticles

FEBS EMBO 2014 Conference -- AUG 30-SEP 04, 2014 -- Paris, FRANCEWOS: 000359666801208…FEBS, EMB

The cytotoxic analysis of free doxorubicin and doxorubicin loaded PHB-MNPs on sensitive and doxorubicin resistant MCF-7 cell lines

FEBS EMBO 2014 Conference -- AUG 30-SEP 04, 2014 -- Paris, FRANCEWOS: 000359666803212…FEBS, EMB

Effect of doxorubicin loaded CS MNPs on cell proliferation in sensitive and doxorubicin resistant MCF-7 cell lines

FEBS EMBO 2014 Conference -- AUG 30-SEP 04, 2014 -- Paris, FRANCEWOS: 000359666803078…FEBS, EMB