A Geographic Study on Level of Markets in Meiktila

The study area, Meiktila is situated in the southwestern part of Mandalay Region. Meiktila has good transport system with various regions of Myanmar. There are 9 markets in Meiktila. The main aim is to study the markets which serve as tertiary system in the study area. Normally the tertiary functions are consumer oriented and they need a certain number of consumers or the threshold population for their existence. They, therefore, used to locate in population centers or in areas with high accessibility. In this paper, the distribution of market is determined by using GIS based buffer analysis. As a result, distribution of these markets is a great difference with respect to their tributary area, size of their functions, transportation facilities, accessibility and location of market place. Therefore, it is needed to build better transport system to develop for levels of markets in the study area

Medical and nursing students’ knowledge of accurate blood pressure measurement procedure in University Malaysia Sarawak

Blood pressure measurement is a basic, frequently-used clinical procedure. Nowadays with increasing use of automatic devices, blood pressure measurement procedure is the most inaccurately performed by the healthcare professionals. The medical and nursing students need good knowledge of accurate measurement procedure for correct diagnosis of hypertension. Our study assessed the knowledge of blood pressure measurement procedure among medical and nursing students in Faculty of Medicine and Health Science of University Malaysia Sarawak (UNIMAS). This was a quantitative, cross-sectional study. Data were collected from total 242 students (171 medical and 71 nursing programmes) with a pre-tested questionnaire including patient’s position, application of instruments, and measurement technique and blood pressure reading. Of 16 items tested, correct answers for 9 items were less than 70%: proper patient’s position (66.9%), choice of the arm (59.1%), appropriate cuff size(51.2%), chest piece (bell or diaphragm) of stethoscope used for listening of Korotkoff sound(11.6%), estimated inflation cuff pressure(66.1%), recommended deflation rate(65.3%), preference of last digit of blood pressure reading(60.7 %), awareness of the auscultatory gap (31.0 %), and habit of palpatory method (27.7%). 51.7% of total students (n= 242) had good knowledge scores. There was no significantly different between the medical and nursing students’ mean knowledge scores (p value=0.099). Our study found that the students need subsequent learning and practices to improve their knowledge for accurate blood pressure resul

Emotional Intelligence Level of Year One and Two Medical Students of University Malaysia Sarawak: Association With Demographic Data

Emotional intelligence is the ability to monitor one’s own and other’s emotions, to discriminate among them, and to guide one’s thinking and actions. It is very important to assess as it helps to reason out our emotional responses. The objective of this study is to assess the emotional intelligence level of Year one and two medical students of UNIMAS. Majority has strength in all the domains except managing emotions domain where 51.5% need attention. No respondent fall into the development priority competency. There were no significant difference among all the domains between two groups but Year 1 students need more attention in managing emotions domain compared to Year 2 students. There was no significant association between demographic characteristics – age, residency, qualification and ethnicity – but there was a significant association (p value of 0.038) in male with empathy domain. Further study should be done on groups spanning from Year 1 to Year 5 as they have a greater difference in age as well as exposure to clinical practice which may have a significant impact on their emotional intelligence

Prevalence of Human Papillomavirus in Women with Abnormal Cervical Smears from Sarawak, Malaysia

Introduction Cervical cancer is common cancer and ranked in fourth place in both incidence and mortality worldwide. It is 3rd most common female cancer in Malaysia with a lifetime risk of 1 in 116. Infection with high-risk oncogenic human papillomavirus (HPV) is recognized as one of the substantial risk factors for the development of cervical cancers. Methods It was a cross-sectional study conducted to determine the prevalence of HPV infection and its subtypes among women with various degrees of abnormal smears, who were seen in the colposcopy clinic of Sarawak General Hospital within six months’ period from January to June 2018. We recruited 56 participants. There were 23 each for an atypical squamous cell of undetermined significance (ASC-US) and low-grade squamous intraepithelial lesion (LSIL) and 10 high- grade squamous intraepithelial lesion (HSIL). DNA was extracted, and HPV genotypes were determined via polymerase chain reaction (PCR) using two primer pairs MY09/MY11 and GP5+/GP6+. Results The age ranged from 23 to 56 years, with a mean age of 42.96 years. HPV was detected in 20 out of 56 (35.7%). There were 6 high-risk oncogenic HPVs (18, 51, 52, 56, 58, 68) detected in participants and the most prevalent subtypes were 18, 52, and 58 (20% each). Four low-risk HPVs detected were 6, 53, 70, and 84. There was a significant association between the severity of cervical lesions and HPV positivity (P < 0.004). HSIL had the highest positive predictive value to have HPV infection as 70% compared to 43.4% of LSIL and 9.3% of ASC-US. Conclusion Distribution of HPV subtypes from women with abnormal smears from Sarawak indicated a high prevalence of HPV 18, 52, and 58. We also identified HPV 70, which has never been reported in West Malaysia. These findings could contribute valuable information for HPV vaccination strategies, particularly for Sarawakian women

Remodeling in the Prefrontal Cortex of a Brain-related to Higher Executive Functions in Adolescence: Its effects on Behavior

Adolescence is a critical stage of the developmental trajectory, where a child’s transition to independent living may result in lead healthy or unhealthy styles. During this period, it is easier to mend an individual as a healthy adult; at the same time, misguided children may enter into risky behaviors. The aim of the study to get an insight into changing brains of adolescents and their behavioral outcomes. The current review search engine proceeds with reviewing the literature in the past through electronic databases such as PubMed, Medline, and Scopus databases using keywords such as adolescent stage, the brain of teenagers, risk behaviors, reduction in gray matter in the prefrontal cortex. The current study reviewed and analyzed 20 articles. The reviewed articles would increase the awareness and insights regarding brain changes and their behavioral outcomes. This insightful information’s drawn out of the study may help professionals and parents who intervene in the adolescent’s problem behaviors

Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants: Piper betle and Murraya koenigii (Curry leaves)

Introduction: Piper betle Linn is one of the most commonly used compounding plants for ethno-medical purposes, with its extract generally used in modern products to enrich their functional efficacy. The extraction methods always lead to differences in the antimicrobial efficacy of methanol extracts of bioactive compounds. Purpose: The study was conducted to screen for bioactive compounds and determine their antimicrobial efficacy in a methanol extract of Piper betle and Murraya koenigi leaves from five different regions. Methodology: The phytochemical screening done according to the procedure that is implied in from Patil, et.al, with minor modifications by the researchers of the current study. Antimicrobial activity was determined; efficacy was measured by disc diffusion analysis. Results: Phytochemical screening revealed the presence of saponin, tannin, terpenoids, alkaloids and flavonoids in the extracts. The methanolic extract of betel leaves from all the selected regions except from Bau exhibited antimicrobial activities. Among them, extract from Kuching and Simunjan have no effect on E. coli. The methanolic extract of curry leaves from Kuching, Balai ringai and Bau have antimicrobial activities against Staph aureus and those from Balai ringai is also active against E.coli. Conclusion: Although there were previous reports of phytochemical screening and antimicrobial activities from the extract of these plants, there were still lack of research conducted on the specimens especially from our local community (Sarawak). The outcome of this study will help us to identify the bioactive compounds of the local samples and give us some pictures of their activities on how to ensure these plants can be brought forward based on the origin of the sample. KEYWORDS: Bioactive Compounds Screening, Antimicrobial Activities of Leave Extract, Palatable Plants, Piper betle and Murraya koenigii

Prevalence of Human Papilloma virus in women with Abnormal Cervical Smears from Sarawak, Malaysia

Introduction: Cervical cancer is common cancer and ranked in fourth place in both incidence and mortality worldwide. It is 3rd most common female cancer in Malaysia with a lifetime risk of 1 in 116. Infection with high-risk oncogenic human papillomavirus (HPV) is recognized as one of the substantial risk factors for the development of cervical cancers. Methods: It was a cross-sectional study conducted to determine the prevalence of HPV infection and its subtypes among women with various degrees of abnormal smears, who were seen in the colposcopy clinic of Sarawak General Hospital within six months’ period from January to June 2018. We recruited 56 participants. There were 23 each for an atypical squamous cell of undetermined significance (ASC-US) and low-grade squamous intraepithelial lesion (LSIL) and 10 high- grade squamous intraepithelial lesion (HSIL). DNA was extracted, and HPV genotypes were determined via polymerase chain reaction (PCR) using two primer pairs MY09/MY11 and GP5+/GP6+. Results: The age ranged from 23 to 56 years, with a mean age of 42.96 years. HPV was detected in 20 out of 56 (35.7%). There were 6 high-risk oncogenic HPVs (18, 51, 52, 56, 58, 68) detected in participants and the most prevalent subtypes were 18, 52, and 58 (20% each). Four low-risk HPVs detected were 6, 53, 70, and 84. There was a significant association between the severity of cervical lesions and HPV positivity (P < 0.004). HSIL had the highest positive predictive value to have HPV infection as 70% compared to 43.4% of LSIL and 9.3% of ASC-US. Conclusion: Distribution of HPV subtypes from women with abnormal smears from Sarawak indicated a high prevalence of HPV 18, 52, and 58. We also identified HPV 70, which has never been reported in West Malaysia. These findings could contribute valuable information for HPV vaccination strategies, particularly for Sarawakian women