MHD Flow of a Micropolar Fluid past a Stretched Permeable Surface with Heat Generation or Absorption

This work considers steady, laminar, MHD flow of a micropolar fluid past a stretched semi-infinite, vertical and permeable surface in the presence of temperature dependent heat generation or absorption, magnetic field and thermal radiation effects. A set of similarity parameters is employed to convert the governing partial differential equations into ordinary differential equations. The obtained self-similar equations are solved numerically by an efficient implicit, iterative, finite-difference method. The obtained results are checked against previously published work for special cases of the problem in order to access the accuarcy of the numerical method and found to be in excellent agreement. A parametric study illustrating the influence of the various physical parameters on the skin friction coefficient, microrotaion coefficient or wall couple stress as well as the wall heat transfer coefficient or Nusselt number is conducted. The obtained results are presented graphically and in tabular form and the physical aspects of the problem are discussed

A General Approach Students’ Attitude towards to Virtual Reality Technology in Distance Education Environment

E-learning has become a prominent and effective role in recent years. The factor of place and time became ineffective in the educational process. So that anyone can learn anywhere in the world. The educational services that benefit the learner during the educational process as well as the factors of assistance are important elements that help in the success of the educational process in the environment of e-learning. The more these services, the greater the benefit from e-learning. But its way of reviewing electronic content is still ineffective. Therefore it was necessary to create a suitable environment for the learner is similar to the real reality. Through which the learner feels the integration and concentration in the academic content as if it were realistic. So, the trend was to take advantage of the virtual reality technology that have become effective in all fields. The use of this technology will help the learner gain mo re realism and make full use of the electronic content. This study reviews the effect of the use of virtual reality technology in the review of the learner\u27s electronic content, as well as the attitudes and opinions of the students of the Business Information Systems program at the Faculty of Commerce, Helwan University, Cairo, Egypt, about the use of this technology and to what extent will effect on change and effectiveness in the quality of educational process

The Impact of Applying ISO Standards Systems on Improving the Quality of the Performance in Higher Educational Institutions in Egypt

Applying ISO 21001:2018 standard ensures that universities have a competitive advantage as well as the achievement of their objectives. This study aims to identify the impact of implementing ISO 21001: 2018 management systems standards on the performance quality of higher education institutions. The study investigates the reasons why private higher education institutions seek ISO standards certificates in general and the specifications of management systems for educational institutions in particular. The study applied a set of statistical testing methods on paired samples as well as independent samples to ensure quality assurance. The study also proposes the required prerequisites that should be considered. The study investigated a hypothesis stating that "there are no statistically significant differences before and after applying the ISO 21001:2018 management systems specification for educational institutions in improving the quality of performance in higher education institutions" which was rejected by conducting an experiment in Future University in Egypt and accepting the alternative hypothesis. The study confirmed the impact of quality which was previously investigated by prior research that has been discussed in this study. The study further presented the need to apply quality based on determined criteria which were not considered in prior studies. Moreover, the study proposed the impact of ISO standards in educational institutions in general and in Egypt in specific. This recommendation is proved by this study to enhance the quality level in educational institutions

Computational and experimental elucidation of the boosted stability and antibacterial activity of ZIF-67 upon optimized encapsulation with polyoxometalates

Water microbial purification is one of the hottest topics that threats human morbidity and mortality. It is indispensable to purify water using antimicrobial agents combined with several technologies and systems. Herein, we introduce a class of nanosized metal organic framework; Zeolitic imidazolate framework (ZIF-67) cages encapsulated with polyoxometalates synthesized via facile one-step co-precipitation method. We employed two types of polyoxometalates bioactive agents; phosphotungstic acid (PTA) and phosphomolybdic acid (PMA) that act as novel antibacterial purification agents. Several characterization techniques were utilized to investigate the morphological, structural, chemical, and physical properties such as FESEM, EDS, FTIR, XRD, and N₂ adsorption/desorption isotherms techniques. The antibacterial assessment was evaluated using colony forming unit (CFU) against both Escherichia coli and Staphylococcus aureus as models of Gram-negative and Gram-positive bacteria, respectively. The PTA@ZIF-67 showed higher microbial inhibition against both Gram-positive and Gram-negative bacteria by 98.8% and 84.6%, respectively. Furthermore, computational modeling using density functional theory was conducted to evaluate the antibacterial efficacy of PTA when compared to PMA. The computational and experimental findings demonstrate that the fabricated POM@ZIF-67 materials exhibited outstanding bactericidal effect against both Gram-negative and Gram-positive bacteria and effectively purify contaminated water

TRA-954: SOLUTION MODEL FOR URBAN TRAFFIC CONGESTION: EGYPTIAN CASE STUDY

Traffic congestion is a major problem in many cities around the world resulting in massive delays, increased fuel wastage, environmental impact and other negative consequences affecting the daily life of each individual. From a transportation engineering point of view, making the correct decision to eliminate such congestion problems can be very difficult for decision-makers who carry the burden of analyzing large quantities of data which could be vague and conflicting in nature. Therefore, an effective and consistent system is required to simplify the decision-making process of the traffic congestion control. Traffic simulation could be that tool. The seriousness of traffic congestion in Egypt is the main motive for the study presented herein. The study aims at developing a model that sets guidelines on how to approach an urban congested traffic area, be able to tackle the problem and choose the effective engineering solution in terms of either geometry and/or structure. Sectors of El Nasr Road, Cairo with a total length of 2.4 km is chosen as a typical example of an urban area with traffic congestion hotspots. It serves as an excellent location to implement the traffic solution model on. The model is developed and implemented as follows: collection of traffic data, diagnosis of the congestion problems in terms of social, commercial, cultural, and behavioral aspects. The analysis of the data finger points out the flag areas by conducting total and peak traffic volume counts, simulation of the existing traffic conditions to get the delayed travel times of vehicles in that area. The analysis of the output would finally help decide whether such problem would be solved by geometric adjustments of the surface or the problem requires a multi-layered intersection

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

Summary: Generating human skeletal muscle models is instrumental for investigating muscle pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial skeletal muscle tissue from human pluripotent stem cells, including induced pluripotent stem cells (iPSCs) from patients with Duchenne, limb-girdle, and congenital muscular dystrophies. 3D skeletal myogenic differentiation of pluripotent cells was induced within hydrogels under tension to provide myofiber alignment. Artificial muscles recapitulated characteristics of human skeletal muscle tissue and could be implanted into immunodeficient mice. Pathological cellular hallmarks of incurable forms of severe muscular dystrophy could be modeled with high fidelity using this 3D platform. Finally, we show generation of fully human iPSC-derived, complex, multilineage muscle models containing key isogenic cellular constituents of skeletal muscle, including vascular endothelial cells, pericytes, and motor neurons. These results lay the foundation for a human skeletal muscle organoid-like platform for disease modeling, regenerative medicine, and therapy development. : Maffioletti et al. generate human 3D artificial skeletal muscles from healthy donors and patient-specific pluripotent stem cells. These human artificial muscles accurately model severe genetic muscle diseases. They can be engineered to include other cell types present in skeletal muscle, such as vascular cells and motor neurons. Keywords: skeletal muscle, pluripotent stem cells, iPS cells, myogenic differentiation, tissue engineering, disease modeling, muscular dystrophy, organoid

Validation of RELAP5 model of experimental test rig simulating the natural convection in MTR research reactors

In an attempt to understand the buildup of natural circulation in MTR pool type upward flow research reactors after loss of power, an experimental test rig was built to simulate the loop of natural circulation in MTR reactors. In this test rig the reactor core is simulated by two electrically heated, rectangular parallel channels. The channel's coolant and surface temperature at different operating conditions were measured. The measurements and their interpretation were published by the first three authors. In the present article the thermal hydraulic behavior of the test rig is complemented by theoretical analysis using RELAP5 system code. The analysis consisting of two parts; in the first part RELAP5 model is validated against the experimental measurements and in the second part the other non-measured hydraulic parameters are presented and analyzed. In spite of the low pressure of the test rig, the results show that RELAP5 Mode 3.3 qualitatively predicts the thermal hydraulic behaviour and the accompanied phenomenon of flow inversion in such facilities. Quantitatively, there is a difference between the predicted and measured values especially the surface temperature of channel's wall. This difference may be return to the uncertainties in initial conditions of experimental runs, the position of the thermocouples which buried inside the heat structure, and the heat transfer package in RELAP5

Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study

La calidad educativa de los centros de hoy depende del nivel de competencias adquirido por sus educadores (Perrenoud, 2002). En este sentido, debemos apostar por un equipo humano formado por sujetos que sepan superarse permanentemente, aptos para ejercer tareas dinámicas y cambiantes y que compartan alternativas para crecer en todos los sentidos. Más todavía, debemos apostar por profesionales capaces de identificar y dominar los procesos que se deben realizar actuando con decisión y responsabilidad. La adquisición de competencias comporta aptitud y actitud para utilizar conocimientos, más concretamente, habilidades y valores, de manera interdisciplinaria, transversal e interactiva en contextos y situaciones que requieren la intervención de contenidos vinculados a las diferentes áreas del currículum (Lleixà, 2007), sin exclusividad, en este caso, del área de Educación Física. Presentamos una propuesta metodológica, el «Paradigma Estratégico para el desarrollo de habilidades competenciales», cuya ejecución implica comprensión, reflexión y discernimiento, teniendo en cuenta la dimensión social de cada situación. El estudio se ha llevado a cabo en la Universidad de Lleida con 40 alumnos de tercer curso de la asignatura «Educación Física y su didáctica». Se pretende valorar el impacto que provoca la implementación del programa «Paradigma estratégico para la adquisición de habilidades competenciales» sobre sus propias percepciones competenciales intrapersonales, antes y después de la aplicación de dicho programa

In ovo protective effects of chicoric and rosmarinic acids against Thiacloprid-induced cytotoxicity, oxidative stress, and growth retardation on newly hatched chicks

Thiacloprid (TH) is a neonicotinoid insecticide employed in agriculture to protect fruits and vegetables against different insects. It showed different deleterious effects on the general health of non-target organisms including birds and animals, however, its developmental toxicity has yet to be fully elucidated. Chicoric (CA) and rosmarinic (RA) acids are polyphenolic compounds with a wide range of beneficial biological activities. In this study, the possible protective effects of CA and RA were investigated in chick embryos exposed in ovo to TH (1mg/egg) with or without CA (100 mg/egg) or RA (100 mg/egg) co-exposure. TH reduced the hatchling body weight, body weight/egg weight, and relative weight of bursa of Fabricius in the one-day-old hatchlings. Examination of the 7-day-old chicks revealed a decline in feed intake, daily weight gain, feed conversion ratio (FCR), and plasma levels of T3, T4, and growth hormone. Serum ALT, AST activities, and total cholesterol levels showed significant elevations. Hepatic MDA was increased with a reduction in SOD activity and GSH level and downregulation of the liver SOD and GST gene expression pattern. Serum IgG and IgM levels were reduced, and various histopathological alterations were noticed in the liver. Co-administration of CA or RA with TH mitigated the toxic effects on hatchlings. When both CA and RA are combined, they present a synergistic protective effect. CA and RA can be used as protective agents against TH toxicity as they improve growth performance and have hepatoprotective and immunostimulant effects in newly hatched chicks

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

Generating human skeletal muscle models is instrumental for investigating muscle pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial skeletal muscle tissue from human pluripotent stem cells, including induced pluripotent stem cells (iPSCs) from patients with Duchenne, limb-girdle, and congenital muscular dystrophies. 3D skeletal myogenic differentiation of pluripotent cells was induced within hydrogels under tension to provide myofiber alignment. Artificial muscles recapitulated characteristics of human skeletal muscle tissue and could be implanted into immunodeficient mice. Pathological cellular hallmarks of incurable forms of severe muscular dystrophy could be modeled with high fidelity using this 3D platform. Finally, we show generation of fully human iPSC-derived, complex, multilineage muscle models containing key isogenic cellular constituents of skeletal muscle, including vascular endothelial cells, pericytes, and motor neurons. These results lay the foundation for a human skeletal muscle organoid-like platform for disease modeling, regenerative medicine, and therapy development. Maffioletti et al. generate human 3D artificial skeletal muscles from healthy donors and patient-specific pluripotent stem cells. These human artificial muscles accurately model severe genetic muscle diseases. They can be engineered to include other cell types present in skeletal muscle, such as vascular cells and motor neurons