136 research outputs found

    An Exploratory Study of the Butterfly Effect Using Agent-Based Modeling

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    This paper provides insights about the behavior of chaotic complex systems, and the sensitive dependence of the system on the initial starting conditions. How much does a small change in the initial conditions of a complex system affect it in the long term? Do complex systems exhibit what is called the "Butterfly Effect"? This paper uses an agent-based modeling approach to address these questions. An existing model from NetLogo library was extended in order to compare chaotic complex systems with near-identical initial conditions. Results show that small changes in initial starting conditions can have a huge impact on the behavior of chaotic complex systems. The term the "butterfly effect" is attributed to the work of Edward Lorenz [1]. It is used to describe the sensitive dependence of the behavior of chaotic complex systems on the initial conditions of these systems. The metaphor refers to the notion that a butterfly flapping its wings somewhere may cause extreme changes in the ecological system's behavior in the future, such as a hurricane

    Validation of the Arabic version of the Social Communication Questionnaire

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    Validated screening and diagnostic tools for autism spectrum disorder for use in Arabic-speaking individuals are scarce. This study validated the Arabic version of the Social Communication Questionnaire. The total study sample included 206 children with autism spectrum disorder and 206 typically developing children (73.8% male; mean age: 8.5 (standard deviation = 2.6) years). The mean Social Communication Questionnaire total score was significantly higher in autism spectrum disorder children than in typically developing children (p < 0.0001). Scores on the three Social Communication Questionnaire subscales also differed significantly between the groups (p < 0.001). Of the 39 items, 37 were endorsed significantly more often in the autism spectrum disorder group. The total Social Communication Questionnaire score did not vary by age or gender. Internal consistency was excellent (alpha = 0.92). In the receiver operating characteristic analysis, the area under the curve for the total score showed excellent discrimination between autism spectrum disorder and typically developing children (area under the curve = 0.95; 95% confidence interval: 0.93–0.97). The areas under the curve for the scale subscores were 0.923 (95% confidence interval: 0.898–0.949) for the social interaction score, 0.872 (95% confidence interval: 0.838–0.905) for the communication score, and 0.856 (95% confidence interval: 0.819–0.893) for the repetitive behaviors score. The findings support the use of the Arabic Social Communication Questionnaire to successfully differentiate children with clinically diagnosed autism spectrum disorder using the established cutoff value for the English version.The authors would like to thank all the staff of the autism centers and schools who contributed in distributing and collecting the SCQ forms. They also would like to thank Western Psychological Services (WPS) staff for their help during the process of translating and reviewing the Arabic SCQ. They acknowledge Jennifer Holmes, ELS, for medical editing. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The study was funded by the Qatar National Research Fund (NPRP 6-093-3-024)

    Factors affecting medical students in formulating their specialty preferences in Jordan

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    <p>Abstract</p> <p>Background</p> <p>In recent years there has been a growing appreciation of the issues of career preference in medicine as it may affect student learning and academic performance. However, no such studies have been undertaken in medical schools in Jordan. Therefore, we carried out this study to investigate the career preferences of medical students at Jordan University of Science and Technology and determine factors that might influence their career decisions.</p> <p>Methods</p> <p>A cross-sectional questionnaire-based survey was carried out among second, fourth and sixth year medical students at the Jordan University of Science and Technology, Irbid, Jordan during the academic year 2006/2007. A total of 440 students answered the questionnaire which covered demographic characteristics, specialty preferences, and the factors that influenced these career preferences. Possible influences were selected on the basis of a literature review and discussions with groups of medical students and physicians. Students were asked to consider 14 specialty options and select the most preferred career preference.</p> <p>Results</p> <p>The most preferred specialty expressed by male students was surgery, followed by internal medicine and orthopaedics, while the specialty most preferred by female students was obstetrics and gynaecology, followed by pediatrics and surgery. Students showed little interest in orthopedics, ophthalmology, and dermatology. While 3.1% of females expressed interest in anesthesiology, no male students did. Other specialties were less attractive to most students.</p> <p>Intellectual content of the specialty and the individual's competencies were the most influential on their preference of specialty. Other influential factors were the "reputation of the specialty", "anticipated income", and "focus on urgent care".</p> <p>Conclusion</p> <p>Surgery, internal medicine, pediatrics, and obstetrics and gynaecology were the most preferred specialty preferences of medical students at Jordan University of Science and Technology.</p

    Glutathione and Adaptive Immune Responses against Mycobacterium tuberculosis Infection in Healthy and HIV Infected Individuals

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    Glutathione (GSH), a tripeptide antioxidant, is essential for cellular homeostasis and plays a vital role in diverse cellular functions. Individuals who are infected with Human immuno deficiency virus (HIV) are known to be susceptible to Mycobacterium tuberculosis (M. tb) infection. We report that by enhancing GSH levels, T-cells are able to inhibit the growth of M. tb inside macrophages. In addition, those GSH-replenished T cell cultures produced increased levels of Interleukin-2 (IL-2), Interleukin-12 (IL-12), and Interferon-gamma (IFN-γ), cytokines, which are known to be crucial for the control of intracellular pathogens. Our study reveals that T lymphocytes that are derived from HIV infected individuals are deficient in GSH, and that this deficiency correlates with decreased levels of Th1 cytokines and enhanced growth of M. tb inside human macrophages

    Spin-polarized supercurrents for spintronics: a review of current progress

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    During the past 15 years a new field has emerged, which combines superconductivity and spintronics, with the goal to pave a way for new types of devices for applications combining the virtues of both by offering the possibility of long-range spin-polarized supercurrents. Such supercurrents constitute a fruitful basis for the study of fundamental physics as they combine macroscopic quantum coherence with microscopic exchange interactions, spin selectivity, and spin transport. This report follows recent developments in the controlled creation of long-range equal-spin triplet supercurrents in ferromagnets and its contribution to spintronics. The mutual proximity-induced modification of order in superconductor-ferromagnet hybrid structures introduces in a natural way such evasive phenomena as triplet superconductivity, odd-frequency pairing, Fulde-Ferrell-Larkin-Ovchinnikov pairing, long-range equal-spin supercurrents, π\pi-Josephson junctions, as well as long-range magnetic proximity effects. All these effects were rather exotic before 2000, when improvements in nanofabrication and materials control allowed for a new quality of hybrid structures. Guided by pioneering theoretical studies, experimental progress evolved rapidly, and since 2010 triplet supercurrents are routinely produced and observed. We have entered a new stage of studying new phases of matter previously out of our reach, and of merging the hitherto disparate fields of superconductivity and spintronics to a new research direction: super-spintronics.Comment: 95 pages, 23 Figures; published version with minor typos corrected and few references adde

    Prediction of diabetic retinopathy: role of oxidative stress and relevance of apoptotic biomarkers

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    Pt and CoB trilayer Josephson π junctions with perpendicular magnetic anisotropy

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    We report on the electrical transport properties of Nb based Josephson junctions with Pt/Co68B32/Pt ferromagnetic barriers. The barriers exhibit perpendicular magnetic anisotropy, which has the main advantage for potential applications over magnetisation in-plane systems of not affecting the Fraunhofer response of the junction. In addition, we report that there is no magnetic dead layer at the Pt/Co68B32 interfaces, allowing us to study barriers with ultra-thin Co68B32. In the junctions, we observe that the magnitude of the critical current oscillates with increasing thickness of the Co68B32 strong ferromagnetic alloy layer. The oscillations are attributed to the ground state phase difference across the junctions being modified from zero to π. The multiple oscillations in the thickness range 0.2 ⩽ dCoB ⩽ 1.4 nm suggests that we have access to the first zero-π and π-zero phase transitions. Our results fuel the development of low-temperature memory devices based on ferromagnetic Josephson junctions
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