162 research outputs found

    Detection of Singular Points from Fingerprint Images Using an Innovative Algorithm

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    Fingerprint scrutiny is typically based on the location and pattern of detected singular points in the images. These singular points (cores and deltas) not only represent the characteristics of local ridge patterns but also determine the topological structure (i.e., fingerprint type) and largely influence the orientation field. In this report, there is an innovative algorithm for singular points detection. After an initial detection using the conventional Poincare Index method, a so-called DORIVAC feature is used to remove spurious singular points. Then, the optimal combination of singular points is selected to minimize the difference between the original orientation field and the model-based orientation field reconstructed using the singular points. A core-delta relation is used as a global constraint for the final selection of singular points. Keywords: Orientation field, Poincare´ Index, Singular points, topological structur

    Could anemia be the reason for dysfunctional cognition???

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    Background: Studies claim that anemia at any time in life can hamper the metabolic processes and subsequently affect the cognitive and behavioral domain of an individual. Late-adolescent girls are one of the most vulnerable groups due to commencement of menstrual cycles, hormonal changes, nutritional deficits etc. It is also the time period where adolescents enter their professional careers in our country where cognition forms the basis of all the learning. This study was focused on seeing whether anemia affects the P300 wave which is a cognitive evoked potential.  Methods: 74 girls of first and second year MBBS were chosen for this study. They were divided into two groups on basis of hemoglobin estimation by cyanmethemoglobin method. A comparative study was done of P300 latency and P300 amplitude between the two groups.Results: Comparison between the anemic group to the control group revealed: Latency of P300 was significantly delayed in the anemic group and amplitude was significantly higher in the control group.Conclusion: The results suggested a better cognitive performance of those having normal hemoglobin levels

    Design and control of electronics based medical emergency system using a Quadcopter

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    Thesedays, there are many incidents that lead to road accidents, some being very severe. These accidents sometimes even result in loss of many lives. One of the major reasons for this loss is the lack of timely first aid. In fact, we observed from our survey conducted at an RTO that most deaths during accidents occur, due to delay or lack of first aid. The project focuses on developing a prototype of the system which would cater to the need of medical emergencies that arise during road accidents. This will be accomplished by use of a quadcopter which will deliver the required first aid. With this project, we are attempting to bring about faster accessibility to the patient, than other present means of medical emergency system. In order to achieve this goal, various means of communication will be utilized. The use of a camera will help to view the accident site. This will help to considerably bring down the death rates caused due to lack of timely first aid during accidents

    Performance of Medium Access Control Protocol in WBAN for Energy Conservation

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    Wireless Communication and Wireless Networking is the popular research in this era. The combination of this is useful method for one step ahead to increase the life of human being who are part of different lifecycle are senior citizen, teen rage and the youth on this world. The issue is to increase the growth of all this living mankind from different serious diseases so the technology and communication is BAN (Body Area Network) through wireless is Wireless Body Area Network. We do the research on the Data link layer of the stack protocol used in WBAN, so to increase the life of battery having the energy with some constraint because one’s the energy is utilized we cannot extend its energy only by replacing the battery so the main innovation for the research will to create the proposed protocol using existing MAC protocol performance so the total energy used for the data transmission should be minimized to increase the battery life. Transmission of data is in different condition may be in Normal, On-demand and Traffic which leads to consume more energy to overcome this there are different MAC protocol for performance in WBAN like S-MAC, Wise-MAC with IEEE 802.15.6 standard

    Effect of Heating Rate on Electromechanical Properties ofPNN–PZT Solid Solution

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    Lead nickel niobate–lead zirconate titanate (Pb(Ni1/3Nb2/3)0.5 –Pb(Zr0.15Ti0.35O3), (PNN-PZT))solid solution was synthesised by columbite  process. Samples sintered at various heating ratesfor 4 h holding and their effect on electromechanical properties have been studied. When heatingrate was 8 °C/min from room temperature to 900 °C and holding for 4 h at 1280 °C, highest relativepermittivity and piezoelectric charge constant were observed, whereas heating rate of 3.5° C/min and holding for 4 h at 1280 °C have shown inferior electromechanical properties and graincoarsening. The piezoelectric charge constant (d33) ~612 pC/N and dielectric constant (e)~ 5950observed in fast heating rate specimen as against to d33~ 137 pC/N and e~4294. XRD result showsthe formation of pyrochlore-free perovskite phase. Fine grains were observed  for fast heatingrate specimens

    Vaccination Targeting a Surface Sialidase of P. acnes: Implication for New Treatment of Acne Vulgaris

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    BACKGROUND: Acne vulgaris afflicts more than fifty million people in the United State and the severity of this disorder is associated with the immune response to Propionibacterium acnes (P. acnes). Systemic therapies for acne target P. acnes using antibiotics, or target the follicle with retinoids such as isotretinoin. The latter systemic treatment is highly effective but also carries a risk of side effects including immune imbalance, hyperlipidemia, and teratogenicity. Despite substantial research into potential new therapies for this common disease, vaccines against acne vulgaris are not yet available. METHODS AND FINDINGS: Here we create an acne vaccine targeting a cell wall-anchored sialidase of P. acnes. The importance of sialidase to disease pathogenesis is shown by treatment of a human sebocyte cell line with recombinant sialidase that increased susceptibility to P. acnes cytotoxicity and adhesion. Mice immunized with sialidase elicit a detectable antibody; the anti-sialidase serum effectively neutralized the cytotoxicity of P. acnes in vitro and P. acnes-induced interleukin-8 (IL-8) production in human sebocytes. Furthermore, the sialidase-immunized mice provided protective immunity against P. acnes in vivo as this treatment blocked an increase in ear thickness and release of pro-inflammatory macrophage inflammatory protein (MIP-2) cytokine. CONCLUSIONS: Results indicated that acne vaccines open novel therapeutic avenues for acne vulgaris and other P. acnes-associated diseases

    Nasopharyngeal Colonization and Invasive Disease Are Enhanced by the Cell Wall Hydrolases LytB and LytC of Streptococcus pneumoniae

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    Background: Streptococcus pneumoniae is a common colonizer of the human nasopharynx and one of the major pathogens causing invasive disease worldwide. Dissection of the molecular pathways responsible for colonization, invasion, and evasion of the immune system will provide new targets for antimicrobial or vaccine therapies for this common pathogen. Methodology/Principal Findings: We have constructed mutants lacking the pneumococcal cell wall hydrolases (CWHs) LytB and LytC to investigate the role of these proteins in different phases of the pneumococcal pathogenesis. Our results show that LytB and LytC are involved in the attachment of S. pneumoniae to human nasopharyngeal cells both in vitro and in vivo. The interaction of both proteins with phagocytic cells demonstrated that LytB and LytC act in concert avoiding pneumococcal phagocytosis mediated by neutrophils and alveolar macrophages. Furthermore, C3b deposition was increased on the lytC mutant confirming that LytC is involved in complement evasion. As a result, the lytC mutant showed a reduced ability to successfully cause pneumococcal pneumonia and sepsis. Bacterial mutants lacking both LytB and LytC showed a dramatically impaired attachment to nasopharyngeal cells as well as a marked degree of attenuation in a mouse model of colonization. In addition, C3b deposition and phagocytosis was more efficient for the double lytB lytC mutant and its virulence was greatly impaired in both systemic and pulmonary models of infection. Conclusions/Significance: This study confirms that the CWHs LytB and LytC of S. pneumoniae are essential virulence factor
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