Using a smartphone app to identify signs of pre-eclampsia and/or worsening blood pressure

Background Hypertensive disorders of pregnancy complicate 10% of pregnancies and can have serious consequences. Aims To explore the experiences of pregnant women with a history of hypertension using an innovative home blood pressure monitoring device. Methods A qualitative study using a grounded theory approach was undertaken. Data were collected through semi-structured interviews. Women were given a blood pressure machine to monitor their blood pressure daily. They inserted their blood pressure results on a smartphone app and answered questions for signs of pre-eclampsia. Participants were followed up every 2 weeks. Findings The results suggested that women wanted a holistic care pathway for the management of hypertension in pregnancy. Three subcategories (‘empowerment’, ‘comparison of care pathways’ and ‘continuity of care’) were also identified. Conclusions The traditional management of hypertension in pregnancy is not holistic. The home blood pressure service was accepted by women and incorporated elements of holistic care but more is required to meet the standard of care that women need

A possible supersymmetric solution to the discrepancy between B -> \phi K_S and B -> \eta' K_S CP asymmetries

We present a possible supersymmetric solution to the discrepancy between the observed mixing CP asymmetries in B -> \phi K_S and B -> \eta' K_S. We show that due to the different parity in the final states of these processes, their supersymmetric contributions from the R-sector have an opposite sign, which naturally explain the large deviation between S_{\phi K_S} and S_{\eta' K_S}. We also consider the proposed mechanisms to solve the puzzle of the observed large branching ratio of B -> \eta' K and study their impact on S_{eta' K_S}.Comment: 4 pages, 2 figure

Monochorionic Twins: A Delicate Balance.

Monochorionic (MC) twins are identical twins who share one placenta, with vascular anastomoses connecting the circulations of both fetuses [...]

Adaptive Horizon Model Predictive Control and Al'brekht's Method

A standard way of finding a feedback law that stabilizes a control system to an operating point is to recast the problem as an infinite horizon optimal control problem. If the optimal cost and the optmal feedback can be found on a large domain around the operating point then a Lyapunov argument can be used to verify the asymptotic stability of the closed loop dynamics. The problem with this approach is that is usually very difficult to find the optimal cost and the optmal feedback on a large domain for nonlinear problems with or without constraints. Hence the increasing interest in Model Predictive Control (MPC). In standard MPC a finite horizon optimal control problem is solved in real time but just at the current state, the first control action is implimented, the system evolves one time step and the process is repeated. A terminal cost and terminal feedback found by Al'brekht's methoddefined in a neighborhood of the operating point is used to shorten the horizon and thereby make the nonlinear programs easier to solve because they have less decision variables. Adaptive Horizon Model Predictive Control (AHMPC) is a scheme for varying the horizon length of Model Predictive Control (MPC) as needed. Its goal is to achieve stabilization with horizons as small as possible so that MPC methods can be used on faster and/or more complicated dynamic processes.Comment: arXiv admin note: text overlap with arXiv:1602.0861

Original approach for thrombolytic therapy in patients with Ilio-femoral deep vein thrombosis: 2 years follow-up

Objective: The aim of the study was to discuss the results of catheter-directed thrombolysis and complementary procedures to treat acute iliofemoral deep vein thrombosis (DVT) evaluating the safety and effectivness of an easy access such as the Great Saphenous Vein. Methods and materials: A total of 22 consecutive patients with iliofemoral thrombosis and two patients with femoro-popliteal thrombosis on recent onset diagnosed with Ultrasound Doppler and contrast venography underwent intrathrombus drip infusion of urokinase while intravenous heparin was continued using saphenical access. Residual venous stenosis were treated in six patients by percutaneous balloon Angioplasty and stenting. All patients underwent routine venous duplex imaging at 30 days, 3 months, 6 months and every 6 months thereafter. Results: Complete patency of thrombosed veins was restored in 22 patients (91 %) with prompt symptomatic relief. There were no major complications in the immediate outcomes. At follow-up, two patients reported a persistant slim iliac vein stenosis, two patients had post-thrombotic syndrome, and two patients showed Deep Vein Reflux. Conclusion: Local thrombolysis using saphenical access was a safe and effective approach for the treatment of acute iliofemoral deep vein thrombosis. It seems to be a valid, easy and safe alternative, reducing the risks of haematoma and venous lesions, which can be observed when using femoral, popliteal, and trans-jugular access

A Sweeping Process Control Problem Subject To Mixed Constraints

In this study, we investigate optimal control problems that involve sweeping processes with a drift term and mixed inequality constraints. Our goal is to establish necessary optimality conditions for these problems. We address the challenges that arise due to the combination of sweeping processes and inequality mixed constraints in two contexts: regular and non-regular. This requires working with different types of multipliers, such as finite positive Radon measures for the sweeping term and integrable functions for regular mixed constraints. For non-regular mixed constraints, the multipliers correspond to purely finitely additive set functions.Comment: 6 page

Neutrino Spin Flavor Precession and Leptogenesis

We argue that \Delta L=2 neutrino spin flavor precession, induced by the primordial magnetic fields, could have a significant impact on the leptogenesis process that accounts for the baryon asymmetry of the universe. Although the extra galactic magnetic fields is extremely weak at present time (about 10^{-9} Gauss), the primordial magnetic filed at the electroweak scale could be quite strong (of order 10^{17} Gauss). Therefore, at this scale, the effects of the spin flavor precession are not negligible. We show that the lepton asymmetry may be reduced by 50% due to the spin flavor precession. In addition, the leptogenesis will have different feature from the standard scenario of leptogenesis, where the lepton asymmetry continues to oscillate even after the electroweak phase transition.Comment: 5 pages, one figure. References adde

Fermion Masses and Mixing in Four and More Dimensions

We give an overview of recent progress in the study of fermion mass and flavor mixing phenomena. Mass matrix ansatze are considered within the SM and SUSY GUTs where some predictive frameworks based on SU(5) and SO(10) are reviewed. We describe a variety of schemes to construct quark mass matrices in extra dimensions focusing on four major classes: models with the SM residing on 3-brane, models with universal extra dimensions, models with split fermions and models with warped extra dimensions. We outline how realistic patterns of quark mass matrices could be derived from orbifold models in heterotic superstring theory. Finally, we address the fermion mass problem in intersecting D-branes scenarios, and present models with D6-branes able to give a good quantitatively description of quark masses and mixing. The role of flavor/CP violation problem as a probe of new physics is emphasized.Comment: a review based on seminars presented by S.K. in different places, 34 pages, late