16 research outputs found

    Archives of the Local Lore Department of the Perm Territory Library

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    Π”Π°Π½ ΠΎΠ±Π·ΠΎΡ€ Π°Ρ€Ρ…ΠΈΠ²Π½Ρ‹Ρ… Ρ„ΠΎΠ½Π΄ΠΎΠ² ΠΎΡ‚Π΄Π΅Π»Π° краСвСдСния ΠŸΠ΅Ρ€ΠΌΡΠΊΠΎΠΉ ΠΊΡ€Π°Π΅Π²ΠΎΠΉ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ, срСди ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… коллСкция Π΄Π΅Π» Ρ‚Π΅Π°Ρ‚Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ дСятСля Π‘. П. ДягилСва, Π»ΠΈΡ‡Π½Ρ‹Π΅ Ρ„ΠΎΠ½Π΄Ρ‹ пСрмских ΠΊΡ€Π°Π΅Π²Π΅Π΄ΠΎΠ² ΠΈ исслСдоватСлСй А. И. Π Π΅ΡƒΡ‚ΠΎΠ²Π°, Π‘. А. Π’ΠΎΡ€ΠΎΠΏΠΎΠ²Π°, М. Н. Π‘Ρ‚Π΅ΠΏΠ°Π½ΠΎΠ²Π°, Π‘. Π€. НиколаСва.There is given a review of the archives of the Local Lore Department of the Perm Territory Library, which include a collection of documents belonging to Sergey Diaghilev, private collections of local lore experts and researches from Perm β€” I.A. Reutov, S.A. Toporov, M.N. Stepanov, S.F. Nikolaev

    Means of expression of incentive modality in Tatar and English languages

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    The relevance of the investigated problem is caused by the need to improve the functional approach to understanding the nature of the content incentive modality. The aim of the study is to identify the means of expression incentive modality in the Tatar and Russian languages, their similarities and differences. The leading approach to the study of the problems is selected descriptive-comparative method with its components - observation, comparison and generalization. The findings suggest that, in both languages there are corresponding counterparts, causing typological commonality; the most frequent way of expressing incentive modality in the English language are modal verbs and modal words, in Tatar - modal words as part of a complex predicate, the use of which depends on the context. Article Submissions may be useful in lecture courses on linguistics, in special courses on the problems of modality, as well as in the practice of teaching the Tatar and English languages.Keywords: language, translation, bilingual, incentive modality, means of expression, typological intention

    The technology of creation of the standard base for socio-economic dimensions

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    Β© Medwell Journals, 2016.Practice education standards for assessing and comparing (comparing/contrasting) heterogeneous properties of controlled processes of socio-economic spheres. Design technique and technology to create a reference framework for processes in socio-economic sphere and on this basis to apply for measuring operations scientific methods of metrology. In this researchers methods of imitating and semantic modeling in a complex with methods of the economical and statistical analysis are used. Possibility of creation of the expert system reproducing technical and operational properties of natural market metrology, formation of general estimated function and a comparable measure of productivity for a set of diverse and multidirectional indicators is discussed. The model of creation of reference base for private indicators providing an integrated rating assessment of a condition of various organizational structures and processes is developed. The conclusion is that in terms of multidirectional indicators the most viable scheme of management of organizational systems is the formation of the reference base, the formation of normative-evaluative, the synthesis of multidimensional processes to one-dimensionality of a single criterion

    Resources for developing the research publication competencies of Russian researchers

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    Introduction. In the last decades, due to the increased number of international research collaborations, the role of auxiliary institutions which contribute to the development of research publication competencies has increased. Competencies are required for writing, preparing, publishing, and promoting scientific articles. The formation of such competencies is carried out at different levels of higher education as part of the current Federal State Educational Standard (FSES), including prorammes of additional professional education, as well as initiatives of auxiliary university departments and non-university organisations. Aim. This article aims to analyse the resources available for the development of research publication competencies in Russia in terms of the opportunities offered by different participants of the educational process. Methodology and research methods. The study compared and analysed open access regulatory documentation, reviewed and systematised data from the websites of auxiliary university departments and non-university organisations, and used data from in-depth interviews. Results. The article describes the prerequisites for the formation of research publication competencies in higher education in Russia. An overview of effective practices to develop such competencies is given, taking into account the national context and available higher education programmes. The article provides an overview of the functionality of auxiliary university departments and non-university organisations, whose activities support publication activity. The role of academic writing teachers, consultants, translators, editors, and reviewers in the development of the competencies of the authors of scientific publications is determined. The importance of the closer interaction of all participants in the publication process is substantiated: authors, translators, and editors of texts; and teachers of scientific writing courses with editors and reviewers of scientific journals. Scientific novelty. The scientific novelty of this article refers to a detailed description of the resources for the development of research publication competencies and their compliance with the requirements of the Federal State Educational Standard, which have not been investigated in such correlation before. Practical significance. The results can be used to develop a set of measures to systematise approaches to developing research publication competencies.Π’Π²Π΅Π΄Π΅Π½ΠΈΠ΅. Π’ послСдниС дСсятилСтия Π² связи с ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ΠΌ объСма ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½Ρ‹Ρ… Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… ΠΊΠΎΠ»Π»Π°Π±ΠΎΡ€Π°Ρ†ΠΈΠΉ возрастаСт Ρ€ΠΎΠ»ΡŒ Π²ΡΠΏΠΎΠΌΠΎΠ³Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… ΡƒΡ‡Ρ€Π΅ΠΆΠ΄Π΅Π½ΠΈΠΉ, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΡΠΏΠΎΡΠΎΠ±ΡΡ‚Π²ΡƒΡŽΡ‚ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΡŽ Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ исслСдоватСлСй. Научно-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Π΅ ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΈ ΠΏΡ€Π΅Π΄ΡΡ‚Π°Π²Π»ΡΡŽΡ‚ собой ΡΠΎΠ²ΠΎΠΊΡƒΠΏΠ½ΠΎΡΡ‚ΡŒ ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ, Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΡ‹Ρ… для написания, ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ, ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΈ ΠΈ продвиТСния Π½Π°ΡƒΡ‡Π½ΠΎΠΉ ΡΡ‚Π°Ρ‚ΡŒΠΈ. Π€ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ, связанных с Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΡΠΊΠΎΠΉ ΠΈ ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒΡŽ российских исслСдоватСлСй, осущСствляСтся Π½Π° Ρ€Π°Π·Π½Ρ‹Ρ… ступСнях Π²Ρ‹ΡΡˆΠ΅Π³ΠΎ образования Π² Ρ€Π°ΠΌΠΊΠ°Ρ… Π΄Π΅ΠΉΡΡ‚Π²ΡƒΡŽΡ‰Π΅Π³ΠΎ Π€Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ государствСнного ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ стандарта (Π€Π“ΠžΠ‘). Π­Ρ‚ΠΎΡ‚ процСсс продолТаСтся Π² Ρ€Π°ΠΌΠΊΠ°Ρ… ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ образования, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΎΡ‚Π΄Π΅Π»ΡŒΠ½Ρ‹Ρ… ΠΈΠ½ΠΈΡ†ΠΈΠ°Ρ‚ΠΈΠ² Π²ΡΠΏΠΎΠΌΠΎΠ³Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… унивСрситСтских ΠΏΠΎΠ΄Ρ€Π°Π·Π΄Π΅Π»Π΅Π½ΠΈΠΉ ΠΈ внСунивСрситСтских ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΉ. ЦСль Π΄Π°Π½Π½ΠΎΠΉ ΡΡ‚Π°Ρ‚ΡŒΠΈ – ΠΏΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΠ΅ΡΡ рСсурсы ΠΏΠΎ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΡŽ Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ Π² России с Ρ‚ΠΎΡ‡ΠΊΠΈ зрСния возмоТностСй, ΠΏΡ€Π΅Π΄Π»Π°Π³Π°Π΅ΠΌΡ‹Ρ… Ρ€Π°Π·Π½Ρ‹ΠΌΠΈ Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌΠΈ процСсса ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ. ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ, ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠΈ. Π’ исслСдовании использовались ΡΡ€Π°Π²Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ-ΡΠΎΠΏΠΎΡΡ‚Π°Π²ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ Π°Π½Π°Π»ΠΈΠ· Π½ΠΎΡ€ΠΌΠ°Ρ‚ΠΈΠ²Π½ΠΎΠΉ Π΄ΠΎΠΊΡƒΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΠΈ ΠΎΡ‚ΠΊΡ€Ρ‹Ρ‚ΠΎΠ³ΠΎ доступа, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΎΠ±Π·ΠΎΡ€ ΠΈ систСматизация Π΄Π°Π½Π½Ρ‹Ρ… с ΠΎΡ„ΠΈΡ†ΠΈΠ°Π»ΡŒΠ½Ρ‹Ρ… сайтов Π²ΡΠΏΠΎΠΌΠΎΠ³Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… унивСрситСтских ΠΏΠΎΠ΄Ρ€Π°Π·Π΄Π΅Π»Π΅Π½ΠΈΠΉ ΠΈ внСунивСрситСтских ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΉ, ΠΌΠ΅Ρ‚ΠΎΠ΄ Π³Π»ΡƒΠ±ΠΈΠ½Π½Ρ‹Ρ… ΠΈΠ½Ρ‚Π΅Ρ€Π²ΡŒΡŽ. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ описаны прСдпосылки формирования Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ Π² систСмС Π²Ρ‹ΡΡˆΠ΅Π³ΠΎ образования Π² России. ΠŸΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ΡΡ ΠΎΠ±Π·ΠΎΡ€ эффСктивных отСчСствСнных ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊ, Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹Ρ… Π½Π° Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ, с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ Π½Π°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ контСкста ΠΈ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌ Π²Ρ‹ΡΡˆΠ΅Π³ΠΎ образования. Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСн ΠΎΠ±Π·ΠΎΡ€ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»Π° Π²ΡΠΏΠΎΠΌΠΎΠ³Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… ΠΏΠΎΠ΄Ρ€Π°Π·Π΄Π΅Π»Π΅Π½ΠΈΠΉ Π²ΡƒΠ·ΠΎΠ² ΠΈ внСунивСрситСтских ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΉ, Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π° Π½Π° ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΡƒ ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ активности. ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Π° Ρ€ΠΎΠ»ΡŒ ΠΏΡ€Π΅ΠΏΠΎΠ΄Π°Π²Π°Ρ‚Π΅Π»Π΅ΠΉ акадСмичСского письма, ΠΊΠΎΠ½ΡΡƒΠ»ΡŒΡ‚Π°Π½Ρ‚ΠΎΠ², ΠΏΠ΅Ρ€Π΅Π²ΠΎΠ΄Ρ‡ΠΈΠΊΠΎΠ², Ρ€Π΅Π΄Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² ΠΈ Ρ€Π΅Ρ†Π΅Π½Π·Π΅Π½Ρ‚ΠΎΠ² Π² Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠΈ ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ Π°Π²Ρ‚ΠΎΡ€ΠΎΠ² Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΉ. Обоснована Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ Π±ΠΎΠ»Π΅Π΅ тСсного взаимодСйствия всСх участников ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ процСсса: Π°Π²Ρ‚ΠΎΡ€ΠΎΠ², ΠΏΠ΅Ρ€Π΅Π²ΠΎΠ΄Ρ‡ΠΈΠΊΠΎΠ² ΠΈ Ρ€Π΅Π΄Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² Π½Π°ΡƒΡ‡Π½ΠΎΠ³ΠΎ тСкста, ΠΏΡ€Π΅ΠΏΠΎΠ΄Π°Π²Π°Ρ‚Π΅Π»Π΅ΠΉ курсов Π½Π°ΡƒΡ‡Π½ΠΎΠ³ΠΎ письма с Ρ€Π΅Π΄Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌΠΈ ΠΈ Ρ€Π΅Ρ†Π΅Π½Π·Π΅Π½Ρ‚Π°ΠΌΠΈ Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… ΠΆΡƒΡ€Π½Π°Π»ΠΎΠ². Научная Π½ΠΎΠ²ΠΈΠ·Π½Π° Π΄Π°Π½Π½ΠΎΠΉ ΡΡ‚Π°Ρ‚ΡŒΠΈ состоит Π² Π΄Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΠΌ описании рСсурсов развития Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ ΠΈ ΠΈΡ… соотвСтствия трСбованиям Π€Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ государствСнного ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ стандарта, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ Π² Ρ‚Π°ΠΊΠΎΠΌ ΡΠΎΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠΈ ΠΏΡ€Π΅ΠΆΠ΄Π΅ Π½Π΅ исслСдовались. ΠŸΡ€Π°ΠΊΡ‚ΠΈΡ‡Π΅ΡΠΊΠ°Ρ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Π½Ρ‹ для Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ комплСкса мСроприятий ΠΏΠΎ систСматизации ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ Π½Π°ΡƒΡ‡Π½ΠΎ-ΠΏΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ.Авторы Π²Ρ‹Ρ€Π°ΠΆΠ°ΡŽΡ‚ Π±Π»Π°Π³ΠΎΠ΄Π°Ρ€Π½ΠΎΡΡ‚ΡŒ Π·Π° ΠΊΠΎΠ½ΡΡƒΠ»ΡŒΡ‚Π°Ρ†ΠΈΠΈ ΠΈ прСдоставлСниС статистичСских Π΄Π°Π½Π½Ρ‹Ρ… Π’. А. Лоскутовой (АНРИ), И. Π’. Π‘Π°ΠΌΠΎΠΉΠ»Π΅Π½ΠΊΠΎ (БтГАУ), И. Π¨Ρ€Π°ΠΉΠ±Π΅Ρ€ ΠΈ Н. Π•ΠΌΠ΅Π»ΡŒΡΠ½ΠΎΠ²ΠΎΠΉ (Π—Π°ΠΏΠ°Π΄Π½ΠΎ-Бибирский ΠΌΠ΅ΠΆΡ€Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹ΠΉ НОЦ), Π•. Π›. Богуславской (ИЀиП Π£Ρ€Πž РАН), И. Π’. ΠžΡ‚Ρ€Π°Π΄Π½ΠΎΠ²ΠΎΠΉ (ΠŸΡ€Π΅Π·ΠΈΠ΄ΠΈΡƒΠΌ Π£Ρ€Πž РАН), Π‘. Π’. ΠœΡ‹Π»ΡŒΠ½ΠΈΠΊΠΎΠ²Ρƒ (Π­ΠΊΠΎ-Π’Π΅ΠΊΡ‚ΠΎΡ€). Авторы Π²Ρ‹Ρ€Π°ΠΆΠ°ΡŽΡ‚ ΠΏΡ€ΠΈΠ·Π½Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π°Π½ΠΎΠ½ΠΈΠΌΠ½Ρ‹ΠΌ Ρ€Π΅Ρ†Π΅Π½Π·Π΅Π½Ρ‚Π°ΠΌ, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ высказали Ρ†Π΅Π½Π½Ρ‹Π΅ Ρ€Π΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°Ρ†ΠΈΠΈ ΠΏΠΎ Π΄ΠΎΡ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΡΡ‚Π°Ρ‚ΡŒΠΈ.The authors express their gratitude to T. A. Loskutova (RASSEP), I. V. Samoilenko (StSAU), I. Schreiber and N. Emelianova (West Siberian Interregional Scientific Centre), E. L. Boguslavskaya (Institute for Philosophy and Law UB RAS), I. V. Otradnova (Presidium UB RAS), S. V. Mylnikov (Eco-Vector) for their consultations and providing statistical data. The authors are grateful to the anonymous reviewers, who provided valuable suggestions for improving the article

    Single cell derived mRNA signals across human kidney tumors.

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    Tumor cells may share some patterns of gene expression with their cell of origin, providing clues into the differentiation state and origin of cancer. Here, we study the differentiation state and cellular origin of 1300 childhood and adult kidney tumors. Using single cell mRNA reference maps of normal tissues, we quantify reference "cellular signals" in each tumor. Quantifying global differentiation, we find that childhood tumors exhibit fetal cellular signals, replacing the presumption of "fetalness" with a quantitative measure of immaturity. By contrast, in adult cancers our assessment refutes the suggestion of dedifferentiation towards a fetal state in most cases. We find an intimate connection between developmental mesenchymal populations and childhood renal tumors. We demonstrate the diagnostic potential of our approach with a case study of a cryptic renal tumor. Our findings provide a cellular definition of human renal tumors through an approach that is broadly applicable to human cancer

    The technology of creation of the standard base for socio-economic dimensions

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    Β© Medwell Journals, 2016.Practice education standards for assessing and comparing (comparing/contrasting) heterogeneous properties of controlled processes of socio-economic spheres. Design technique and technology to create a reference framework for processes in socio-economic sphere and on this basis to apply for measuring operations scientific methods of metrology. In this researchers methods of imitating and semantic modeling in a complex with methods of the economical and statistical analysis are used. Possibility of creation of the expert system reproducing technical and operational properties of natural market metrology, formation of general estimated function and a comparable measure of productivity for a set of diverse and multidirectional indicators is discussed. The model of creation of reference base for private indicators providing an integrated rating assessment of a condition of various organizational structures and processes is developed. The conclusion is that in terms of multidirectional indicators the most viable scheme of management of organizational systems is the formation of the reference base, the formation of normative-evaluative, the synthesis of multidimensional processes to one-dimensionality of a single criterion

    The technology of creation of the standard base for socio-economic dimensions

    No full text
    Β© Medwell Journals, 2016.Practice education standards for assessing and comparing (comparing/contrasting) heterogeneous properties of controlled processes of socio-economic spheres. Design technique and technology to create a reference framework for processes in socio-economic sphere and on this basis to apply for measuring operations scientific methods of metrology. In this researchers methods of imitating and semantic modeling in a complex with methods of the economical and statistical analysis are used. Possibility of creation of the expert system reproducing technical and operational properties of natural market metrology, formation of general estimated function and a comparable measure of productivity for a set of diverse and multidirectional indicators is discussed. The model of creation of reference base for private indicators providing an integrated rating assessment of a condition of various organizational structures and processes is developed. The conclusion is that in terms of multidirectional indicators the most viable scheme of management of organizational systems is the formation of the reference base, the formation of normative-evaluative, the synthesis of multidimensional processes to one-dimensionality of a single criterion

    The technology of creation of the standard base for socio-economic dimensions

    Get PDF
    Β© Medwell Journals, 2016.Practice education standards for assessing and comparing (comparing/contrasting) heterogeneous properties of controlled processes of socio-economic spheres. Design technique and technology to create a reference framework for processes in socio-economic sphere and on this basis to apply for measuring operations scientific methods of metrology. In this researchers methods of imitating and semantic modeling in a complex with methods of the economical and statistical analysis are used. Possibility of creation of the expert system reproducing technical and operational properties of natural market metrology, formation of general estimated function and a comparable measure of productivity for a set of diverse and multidirectional indicators is discussed. The model of creation of reference base for private indicators providing an integrated rating assessment of a condition of various organizational structures and processes is developed. The conclusion is that in terms of multidirectional indicators the most viable scheme of management of organizational systems is the formation of the reference base, the formation of normative-evaluative, the synthesis of multidimensional processes to one-dimensionality of a single criterion

    Precise identification of cancer cells from allelic imbalances in single cell transcriptomes.

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    A fundamental step of tumour single cell mRNA analysis is separating cancer and non-cancer cells. We show that the common approach to separation, using shifts in average expression, can lead to erroneous biological conclusions. By contrast, allelic imbalances representing copy number changes directly detect the cancer genotype and accurately separate cancer from non-cancer cells. Our findings provide a definitive approach to identifying cancer cells from single cell mRNA sequencing data
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