Developmental Strategies of Proliferating Cryptocurrencies – A Case Study on Solana

Cryptocurrencies have disrupted the financial world and created opportunities for businesses to raise capital. However, not all cryptocurrencies have been successful, and identifying the critical factors for success is essential. Many successful cryptocurrencies have established ecosystems and partnerships with leading companies. The purpose of this article is to explore the strategies for building an ecosystem of cryptocurrencies to promote their development and adoption. By examining successful cases and identifying the associated technological innovations and external partnerships, this study aims to provide empirical evidence and insights into the proliferation of cryptocurrencies

Chronic opioid pretreatment potentiates the sensitization of fear learning by trauma.

Despite the large comorbidity between PTSD and opioid use disorders, as well as the common treatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to subsequently modify PTSD-related behavior has not been well studied. Using the stress-enhanced fear learning (SEFL) model for PTSD, we characterized the impact of chronic opioid regimens on the sensitization of fear learning seen following traumatic stress in mice. We demonstrate for the first time that chronic opioid pretreatment is able to robustly augment associative fear learning. Highlighting aversive learning as the cognitive process mediating this behavioral outcome, these changes were observed after a considerable period of drug cessation, generalized to learning about multiple aversive stimuli, were not due to changes in stimulus sensitivity or basal anxiety, and correlated with a marker of synaptic plasticity within the basolateral amygdala. Additionally, these changes were not observed when opioids were given after the traumatic event. Moreover, we found that neither reducing the frequency of opioid administration nor bidirectional manipulation of acute withdrawal impacted the subsequent enhancement in fear learning seen. Given the fundamental role of associative fear learning in the generation and progression of PTSD, these findings are of direct translational relevance to the comorbidity between opioid dependence and PTSD, and they are also pertinent to the use of opioids for treating pain resulting from traumas involving physical injuries

A heuristic for the container loading problem: A tertiary-tree-based dynamic space decomposition approach

Increasing fuel costs, post-911 security concerns, and economic globalization provide a strong incentive for container carriers to use available container space more efficiently, thereby minimizing the number of container trips and reducing socio-economic vulnerability. A heuristic algorithm based on a tertiary tree model is proposed to handle the container loading problem (CLP) with weakly heterogeneous boxes. A dynamic space decomposition method based on the tertiary tree structure is developed to partition the remaining container space after a block of homogeneous rectangular boxes is loaded into a container. This decomposition approach, together with an optimal-fitting sequencing and an inner-right-corner-occupying placement rule, permits a holistic loading strategy to pack a container. Comparative studies with existing algorithms and an illustrative example demonstrate the efficiency of this algorithm

Social Media Analytics for Non-Governmental Organizations

Social media has provided promotion and communication channels for organizations to reach their target audience efficiently and cost-effectively. Despite wide social media analytics applications in different areas, scant studies focus on NGOs. This research analyzes the use of social media by a well-known NGO, the Hong Kong Generation Next Arts Limited (HKGNA), on its presence and user sentiment on Twitter and Facebook to evaluate the brand image, engagement conditions, and promotion effectiveness. These findings showed a low usage frequency of their Twitter channel. Despite the overall positive sentiment, there are some deviations from their charity mission. Yet, their Facebook channel serves well for publicity, and the interaction is relatively active. Thus, more measures are necessary to improve the digital relationship between HKGNA and its targeted audience. Moreover, this methodology for data analysis serves as an example for other NGOs to improve their communication

Unveiling multi-scale laser dynamics through time-stretch and time-lens spectroscopies

Spectro-temporal studies on the nonlinear physics of complex laser dynamics are essential in approaching its ultimate performance as well as understanding interdisciplinary problems. Unfortunately, it has long been limited by the insufficient spectro-temporal resolving power of conventional temporal and spectral analyzers, particularly when an indefinite optical signal ensemble contains polychromatic mixtures of continuous-wave (CW) and short pulse. In this work, we propose a real-time optical spectro-temporal analyzer (ROSTA) with three synchronized processing channels (i.e., multi-core) for single-shot studies on laser dynamics. It simultaneously provides temporal resolutions of ~70 ps in the time domain and 10’s ns (or 10’s MHz frame rate) in the spectral domain, as well as a high spectral resolution for multiscale optical inputs, i.e., ranging from CW to fs pulses. Its non-trivial record length of up to 6.4 ms enables continuous observations of non-repetitive optical events over an extensive time period ― equivalent to a propagation distance of ~1900 km. To showcase its practical applications, ROSTA is applied to visualize the onset of passive mode-locking of a fiber laser, and interesting phenomena, i.e., evolution from quasi-CW noise burst to strong shock, transition from fluctuation to mode-locking, and coexistence of CW and mode-locked pulses, have been spectro-temporally observed in a single-shot manner for the first time. It is anticipated that ROSTA will be a powerful technology for spectro-temporal optical diagnosis in different areas involving polychromatic transients

The Role of Celebrities’ Personality Traits & Endorsement on Consumers’ Online Brand Defending and Purchase Behaviour

Celebrity endorsements are widely adopted as part of the marketing strategies for many brands, given celebrities can engage their fans to patronize the brand and to distribute celebrity-featuring promotion messages online. With the proliferation of the Internet, these fans may also defend their beloved celebrities when they are being attacked. However, whether a consumer’s positive attitude to the endorser would impact their behaviour toward the endorsed brand remains unclear. Qualitatively studying based on a few leading online communities, we explored the impact of attitude towards brand-endorsing celebrities on online consumers’ behaviour (likelihood of brand defending and purchase intention), which would foster the brand’s electronic word-of-mouth (eWOM). We also identified several endorsers’ traits that drive consumers’ attitudes towards brand-endorsing celebrities and the role of exposure frequency of celebrity-featured advertisements on consumers’ attitudes towards the endorsed brand

Video-rate centimeter-range optical coherence tomography based on dual optical frequency combs by electro-optic modulators

Imaging speed and range are two important parameters for optical coherence tomography (OCT). A conventional video-rate centimeter-range OCT requires an optical source with hundreds of kHz repetition rate and needs the support of broadband detectors and electronics (>1 GHz). In this paper, a type of video-rate centimeter-range OCT system is proposed and demonstrated based on dual optical frequency combs by leveraging electro-optic modulators. The repetition rate difference between dual combs, i.e. the A-scan rate of dual-comb OCT, can be adjusted within 0~6 MHz. By down-converting the interference signal from optical domain to radio-frequency domain through dual comb beating, the down-converted bandwidth of the interference signal is less than 22.5 MHz which is at least two orders of magnitude lower than that in conventional OCT systems. A LabVIEW program is developed for video-rate operation, and the centimeter imaging depth is proved by using 10 pieces of 1-mm thick glass stacked as the sample. The effective beating bandwidth between two optical comb sources is 7 nm corresponding to ~108 comb lines, and the axial resolution of the dual-comb OCT is 158 µm. Dual optical frequency combs provide a promising solution to relax the detection bandwidth requirement in fast long-range OCT systems

Vesicular glutamatergic transmission in noise-induced loss and repair of cochlear ribbon synapses

Noise-induced excitotoxicity is thought to depend on glutamate. However, the excitotoxic mechanisms are unknown, and the necessity of glutamate for synapse loss or regeneration is unclear. Despite absence of glutamatergic transmission from cochlear inner hair cells in mice lacking the vesicular glutamate transporter-3