157 research outputs found

    *Are you learnin' us today, Miss?*: developing assessment for learning as personalised practice

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    Impact Of Mad Money Stock Recommendations: Merging Financial and Marketing Perspectives

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    This article relies on advertising and persuasive communications theories to uncover persistent variations in investor response to television stock recommendations targeting naive investors. The authors use an event study methodology to determine the size of the next-day abnormal market reaction to recommendations on Mad Money with Jim Cramer. Although viewers are actively looking for recommendations, the results show that any individual recommendation is still subject to many of the same communication challenges as traditional advertisements. A regression analysis finds that traditional advertising variables, such as message length, recency-primacy effects, information clutter, and source credibility, influence the size of the market reaction to a buy recommendation. The authors discuss implications for marketers, managers of public companies, and those interested in public policy aspects related to televised stock recommendations

    Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal

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    This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with the federal drug schedules, the authors visit some of the medical and public health issues vis-à-vis safe injection facilities (SIFs). Insite, a successful Canadian SIF, has been thoroughly researched as it represents a paradigm for which a Philadelphia CUES can expand upon. Also, the existing criticisms against SIFs are revisited while critically unpackaged and responded to in favor of the establishment. In the main section, the authors propose the layout and services of the upcoming CUES, much of which would be in congruent to Vancouver’s Insite. On the other hand, the CUES would be distinct from Insite, as the authors emphasize, in that it will offer an information center run by individuals in recovery and place additional emphasis on early education for young healthcare professionals by providing them a platform to work at the site. The paper will also briefly investigate the implementation of a CUES site under an ethical scope of the Harm Reduction Theory. Lastly, the authors recommend some strategic plans that the Philadelphia City government may consider employing at this crucial stage

    Deaths in Custody; Is Ireland’s Investigative Process Compliant with Article 2 of the European Convention on Human Rights?

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    This research report examines the investigative process regarding deaths in custody in Ireland and other jurisdictions. The students completed this research as part of the LLB Bachelor of Law programme. This project was designed and completed in collaboration with the Irish Penal Reform Trust

    Comprehensive User Engagement Sites (CUES): Is This a Viable Option for the Opioid Epidemic in Philadelphia?

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    INTRODUCTION: Opioid drug abuse has become an increasing concern throughout the United States, especially within the Philadelphia region. In 2017, the number of deaths by drug overdose were four times that of deaths by homicide. In addition, a total of 935 cases of secondary conditions due to needle sharing such as HIV and HCV occurred during the past year. The opioid epidemic has caused a public health emergency and any measures that could decrease the morbidity and mortality associated with opioid abuse are vital. A current proposal to combat this issue in Philadelphia is the implementation of a Comprehensive User Engagement Site (CUES); a site intended to offer medical resources and assistance for opioid users. This study analyzed the clinical, ethical, and economic considerations associated with a potential CUES site in Philadelphia. METHODS: A review of the literature was conducted using PubMed, EMBASE, and various public data sources. Search keywords included the history and efficacy of safe injection facilities (SIFs), their implementation to Philadelphia, and other related terms. Semi-structured discussion sessions were also conducted among members of the Institute of Clinical Bioethics at Saint Joseph’s University, resident physicians at Mercy Health System, and PCOM medical students. Topics of discussion included the risks, benefits, and ethics involved in initiating a CUES in Philadelphia, with research regarding past SIFs being uses as a comparative model. RESULTS: The impact of a CUES in Philadelphia has been estimated to avert 3-48 cases of HIV infections annually, 15-213 cases of HCV infections annually, and between 24-76 deaths. In addition, the site is estimated to reduce costs due to skin infection by 1.51.9Millionannually,costsduetooverdosedeathsbyupwardsof1.5-1.9 Million annually, costs due to overdose deaths by upwards of 75 Million annually, as well as costs related to ambulance and hospital visits by 123,000and123,000 and 300,000 per averted case respectively. Ethical analysis revealed that safe injection is ethically permissible given the primary intent is to limit the user’s exposure to harm. DISCUSSION: The implementation of a CUES in Philadelphia may be an effective tool to address opioid crisis. It would reduce healthcare costs through prevention of drug-related sequelae, offer treatment and resources for people seeking to overcome their opioid dependence, and act as an educational opportunity for future healthcare professionals by promoting student engagement with marginalized populations

    A smart city-smart bay project - establishing an integrated water monitoring system for decision support in Dublin Bay

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    Environmental and water quality monitoring is key to measuring and understanding the chemical and biological quality of water and for taking reactive remedial action. Over the coming years, monitoring of water bodies will increase within Europe, in order to comply with the requirements of the Water Framework Directive (WFD, Council Directive 2000/60/EC), and globally owing to pressure from climate change. The establishment of high quality long-term monitoring programmes is regarded as essential if the implementation of the WFD is to be effective. However, the traditional spot/grab sampling using conventional sampling and laboratory based techniques can introduce a significant financial burden, and is unlikely to provide a reasonable estimate of the true maximum and/or mean concentration for a particular physico-chemical variable in a water body with marked temporal variability. When persistent fluctuations occur, it is likely only to be detected through continuous measurements, which have the capability of detecting sporadic peaks of concentration. The aim of this work is to demonstrate the potential for continuous monitoring data in decision support as part of a smart city project. The multi-modal data system shows potential for low-cost sensing in complex aquatic environments around the city. Continuous monitoring data from both visual and water quality sensors is collected and data from grab samples collected support the observations of trends in water quality

    Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance

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    OBJECTIVE—Skeletal muscle insulin resistance is associated with lipid accumulation, but whether insulin resistance is due to reduced or enhanced flux of long-chain fatty acids into the mitochondria is both controversial and unclear. We hypothesized that skeletal muscle–specific overexpression of the muscle isoform of carnitine palmitoyltransferase 1 (CPT1), the enzyme that controls the entry of long-chain fatty acyl CoA into mitochondria, would enhance rates of fatty acid oxidation and improve insulin action in muscle in high-fat diet insulin-resistant rats

    On-Orbit Data and Validation of Astra\u27s ACE Electric Propulsion System

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    The first ACE propulsion system reached orbit on July 1st 2021 as part of Spaceflight’s demonstration of the Sherpa-LTE all-electric Orbital Transfer Vehicle (OTV). We are now able to share on-orbit data and have successfully verified the on-orbit performance of the ACE propulsion system, using xenon propellent. The mission objective was to lower altitude and use on-orbit data to derive performance, correlating the propulsion system’s performance to ground test data. The demonstration consisted of activating the propulsion system for 5- minute durations at a total input power of 340 W into the Power Processing Unit (PPU). Altitude change and propellant usage were used to derive thrust and total specific impulse. On-orbit performance is compared to ground test data in Table 1. Averaged performance is within one standard deviation of ground test data. Astra considers this a validation of system performance, as well as the ground test facilities used to test propulsion systems. On-orbit thrust has a large standard deviation as a result of the limited data sampling rate and measurement errors, rather than variability in thruster performance. Figure 1 shows the thruster operating on-orbit. The Astra team gratefully acknowledges the support of Spaceflight, Inc., the U.S. Air Force, and Defense Innovation Unit (DIU) without which this mission would not have been possible
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