On the Nature of Particulate Emissions from DISI Engines at Cold-Fast-Idle

Particulate emissions from a production gasoline direct injection spark ignition engine were studied under a typical cold-fast-idle condition (1200 rpm, 2 bar NIMEP). The particle number (PN) density in the 22 to 365 nm range was measured as a function of the injection timing with single pulse injection and with split injection. Very low PN emissions were observed when injection took place in the mid intake stroke because of the fast fuel evaporation and mixing processes which were facilitated by the high turbulent kinetic energy created by the intake charge motion. Under these conditions, substantial liquid fuel film formation on the combustion chamber surfaces was avoided. PN emissions increased when injection took place in the compression stroke, and increased substantially when the fuel spray hit the piston. A conceptual model was established for the particulate matter (PM) formation process in which PM is formed by pyrolysis after the normal premixed flame passage in fuel rich plumes originating from liquid films on the cylinder walls. The pyrolysis process is supported by heat conducted from the hot burned gases outside the plume and by the energy released by the pyrolysis reactions. Thus, the “pool fire” often observed is not a diffusion flame since the small amount of residual oxygen in the burned gases cannot support such a flame. The luminosity is radiation from the hot soot particles which are not oxidized after being formed in the pyrolysis reactions. This model was supported by the PN data obtained from sweeping the charge equivalence ratio from lean to rich.Borg-Warner CorporationChrysler CorporationFord Motor CompanyGeneral Motors Corporatio

Field-induced charge transport at the surface of pentacene single crystals: a method to study charge dynamics of 2D electron systems in organic crystals

A method has been developed to inject mobile charges at the surface of organic molecular crystals, and the DC transport of field-induced holes has been measured at the surface of pentacene single crystals. To minimize damage to the soft and fragile surface, the crystals are attached to a pre-fabricated substrate which incorporates a gate dielectric (SiO_2) and four probe pads. The surface mobility of the pentacene crystals ranges from 0.1 to 0.5 cm^2/Vs and is nearly temperature-independent above ~150 K, while it becomes thermally activated at lower temperatures when the induced charges become localized. Ruling out the influence of electric contacts and crystal grain boundaries, the results contribute to the microscopic understanding of trapping and detrapping mechanisms in organic molecular crystals.Comment: 14 pages, 4 figures. Submitted to J. Appl. Phy

239 + 240Pu from “contaminant” to soil erosion tracer: Where do we stand?

As soil erosion is the major threat to one of the most essential resources of humankind, methods to quantify soil redistribution are crucial for agro-environmental assessment as well as for optimisation of soil conservation practices. The use of fallout radionuclides (FRN) as soil redistribution tracers is, next to modelling, currently the most promising approach for assessing soil erosion. This review aims to evaluate the suitability of Plutonium (Pu) in general and the 239+240Pu isotopes in particular as soil redistribution tracers. It provides information on its origin, distribution and behaviour in soils and in the environment. Analytical methods, their recent advances as well as limitations, are discussed. To establish the current state of knowledge and to deepen our understanding, particular attention is given to the main existing achievements and findings based on using 239+240Pu as soil erosion tracer in agroecosystems. We further discuss similarities and differences to other more mature FRN techniques such as the 137Cs based approach which has been until now the most widely used method. We conclude that 239+240Pu has the potential to become the next generation of soil redistribution tracer compared to the more mature FRN techniques mostly due to (i) its long half-life guaranteeing its long-term availability in the environment, (ii) its analytical advantage in terms of measurement precision and measurement time and (iii) its greater homogeneity at reference sites due to its main origin from past atmospheric nuclear weapon tests. In identifying some key future research opportunities and needs, we hope to refine the efficiency of this promising agro-environmental tracer for effective soil redistribution studies under future climate and land use change

Nosocomial nontyphoidal salmonellosis after antineoplastic chemotherapy: reactivation of asymptomatic colonization?

An increased frequency of nontyphoidal salmonellosis is well established in cancer patients, but it is unclear whether this represents increased susceptibility to exogenous infection or opportunistic, endogenous reactivation of asymptomatic carriage. In a retrospective study, a simple case definition was used to identify the probable presence of reactivation salmonellosis in five cancer patients between 1996 and 2002. Reactivation salmonellosis was defined as the development of nosocomial diarrhea >72h after admission and following the administration of antineoplastic chemotherapy in an HIV-seronegative cancer patient who was asymptomatic on admission, in the absence of epidemiological evidence of a nosocomial outbreak. Primary salmonellosis associated with unrecognized nosocomial transmission or community acquisition and an unusually prolonged incubation period could not entirely be ruled out. During the same time period, another opportunistic infection, Pneumocystis pneumonia, was diagnosed in six cancer patients. Presumably, asymptomatic intestinal Salmonella colonization was converted to invasive infection by chemotherapy-associated intestinal mucosal damage and altered innate immune mechanisms. According to published guidelines, stool specimens from patients hospitalized for longer than 72h should be rejected unless the patient is neutropenic or ≧65 years old with significant comorbidity. However, in this study neutropenia was present in only one patient, and four patients were <65 years old. Guidelines should thus be revised in order not to reject stool culture specimens from such patients. In cancer patients, nosocomial salmonellosis can occur as a chemotherapy-triggered opportunistic reactivation infection that may be similar in frequency to Pneumocystis pneumoni

Partnerships and Public Service: Normative Issues for Journalists in Converged Newsrooms

As media companies test and implement newsroom “convergence,” growing numbers of journalists are producing content not only for their own employer but also for other media outlets with which that employer has a business relationship. This article, based on case studies in four converged news markets, explores journalists’ perceptions of normative pressures in this new media environment, particularly in relation to the overarching concept of public service. The findings suggest that although journalists do not see convergence itself as posing significant ethical problems, they do raise concerns related to specific components of public service, including a devotion to accuracy, an avoidance of sensationalism, and independence from economic pressures

Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group for Clinical Cancer Research (SAKK)

Background: Predictive factors of rituximab efficacy and its effect on the immune system are still not defined. Patients and methods: Three hundred and six patients with follicular or mantle cell lymphoma received four weekly doses of rituximab (induction) and no further treatment (arm A) or four more doses at 2-month intervals (arm B). Results: Response rate to induction was 44%. Independent predictive factors for response were disease bulk <5 cm, follicular histology, normal hemoglobin and low lymphocyte count. Factors associated with event-free survival (EFS) were having responded to induction, having received not more than one line of therapy, Ann Arbor stage I-III, high lymphocyte count, disease bulk <5 cm, Fc-gamma receptor genotype VV and receiving prolonged treatment. B cells were suppressed by treatment but recovered after a median of 12 months in arm A and 18 months in arm B. The median IgM level after 1 year was normal in arm A but was decreased to 73% of baseline in arm B. We observed 24 serious adverse events, equally distributed between arms. Ten patients receiving induction only and six patients receiving prolonged treatment developed a second tumor. Conclusions: We defined the characteristics predicting response and EFS to rituximab. Prolonged treatment results in longer EFS at the cost of a longer reduction in B cell and IgM levels, but without additional clinical toxicit