Per Family Error Rates: A Response

As the authors note, the familywise error rate (FWER) is used rather often, whereas the per-family error rate (PFER) is not. Is this as it should be? It would seem that no universal answer is possible, as context determines which is more appropriate in any given application. In the general scenario of testing the benefit of an intervention, one might ideally want an error rate that aligns with the decision for benefit. In most cases the FWER does this pretty well, while allowing one to identify those endpoints for which benefit exists. The PFER does not seem to have any advantage over the FWER in this general testing scenario. Perhaps in some other scenarios the PFER might have some reasonable role

The Stakes in Bayh-Dole: Public Values Beyond the Pace of Innovation

Evaluation studies of the Bayh-Dole Act are generally concerned with the pace of innovation or the transgressions to the independence of research. While these concerns are important, I propose here to expand the range of public values considered in assessing Bayh-Dole and formulating future reforms. To this end, I first examine the changes in the terms of the Bayh-Dole debate and the drift in its design. Neoliberal ideas have had a definitive influence on U.S. innovation policy for the last thirty years, including legislation to strengthen patent protection. Moreover, the neoliberal policy agenda is articulated and justified in the interest of “competitiveness.” Rhetorically, this agenda equates competitiveness with economic growth and this with the public interest. Against that backdrop, I use Public Value Failure criteria to show that values such as political equality, transparency, and fairness in the distribution of the benefits of innovation, are worth considering to counter the “policy drift” of Bayh-Dole

Development and Psychometric Evaluation of Healthcare Access Measures among Women with Ovarian Cancer

Several proposed theoretical frameworks have defined the complex nature of healthcare access (HCA) [...