2,232 research outputs found

    Journeys towards expertise in technology-supported teaching

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    Expertise in technology-supported teaching needs to be understood from multi-dimensional perspectives and influences, if raising teacher quality is a desired goal of education services. This study aimed to uncover the interactive influences of teachers\u27 pedagogical practices, learning experiences and personal characteristics and how their decisions impacted upon their growth in expert technology-supported teaching. A mixed methods approach incorporated case study techniques, use of quantitative and qualitative data and was informed by grounded theory. Five female primary teachers participated in this research which was conducted during one year over two data collection stages in a technology-supportive independent Australian girls\u27 school. Variations of expertise were most evident in teachers\u27 pedagogical practices, attributable to their technological, pedagogical and content knowledge and beliefs about student learning. These were apparent in the design, delivery and management of student learning activities, with and without digital resources and tools. Common to all was the strength of performance self-efficacy beliefs, desire for excellence and the motivational challenges afforded by technologies to practices and approaches to learning. Particular experiences and influences on learning were perceived by teachers as significant in their journeys of growth, namely 1) accessing the knowledge and modelling strategies of a dedicated curriculum resource teacher, 2) engaging in collaborative activities and feeling part of a team, 3) observing colleagues at work, and 4) being committed to staying abreast of new ideas by spending time alone to play and learn in the non-threatening environment of technology. A distinctive feature of their professional agency was illustrated by pro-active attitudes to change and taking ownership for decisions. These deliberate choices made to advance professional growth over time were epitomised by changes in professional roles, changes within school systems and changes to practices, incorporating risk-taking actions. Expert practices with technology need to be sustained through perseverance and dedication to learning and practice. When the extent of a teacher\u27s expertise is distinguished by referring to descriptors along continuum pathways, this is an encouragement to all teachers to pursue excellence in technology-supported teaching practices

    Nonequilibrium Green's function theory for nonadiabatic effects in quantum electron transport

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    We develop nonequilibribrium Green's function based transport theory, which includes effects of nonadiabatic nuclear motion in the calculation of the electric current in molecular junctions. Our approach is based on the separation of slow and fast timescales in the equations of motion for the Green's functions by means of the Wigner representation. Time derivatives with respect to central time serves as a small parameter in the perturbative expansion enabling the computation of nonadiabatic corrections to molecular Green's functions. Consequently, we produce series of analytic expressions for non-adiabatic electronic Green's functions (up to the second order in the central time derivatives); which depend not solely on instantaneous molecular geometry but likewise on nuclear velocities and accelerations. Extended formula for electric current is derived which accounts for the non-adiabatic corrections. This theory is concisely illustrated by the calculations on a model molecular junction

    Colorectal Cancer Through Simulation and Experiment

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    Colorectal cancer has continued to generate a huge amount of research interest over several decades, forming a canonical example of tumourigenesis since its use in Fearon and Vogelstein’s linear model of genetic mutation. Over time, the field has witnessed a transition from solely experimental work to the inclusion of mathematical biology and computer-based modelling. The fusion of these disciplines has the potential to provide valuable insights into oncologic processes, but also presents the challenge of uniting many diverse perspectives. Furthermore, the cancer cell phenotype defined by the ‘Hallmarks of Cancer’ has been extended in recent times and provides an excellent basis for future research. We present a timely summary of the literature relating to colorectal cancer, addressing the traditional experimental findings, summarising the key mathematical and computational approaches, and emphasising the role of the Hallmarks in current and future developments. We conclude with a discussion of interdisciplinary work, outlining areas of experimental interest which would benefit from the insight that mathematical and computational modelling can provide

    Spectral Graph Theory and Research

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    Our topic of study was Spectral Graph Theory. We studied the algebraic methods used to study the properties of graphs (networks) and became familiar with the applications of network analysis. We spent a significant amount of time studying the way virus’s spread on networks, with particular applications to Covid-19. We also investigated the relationship between graph spectra and structural properties

    Getting inside the black box of technology integration in education: Teachers\u27 stimulated recall of classroom observations

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    This study explored the black box of technology integration through the stimulated recall of teachers who showed proficiency in the use of technology to support teaching and learning. More particularly, the aim of the study was to examine how these teachers use technology in their lessons and to gain deeper insights into the multifaceted influences affecting their current practices. In order to explore this black box, observations and stimulated recall interviews with primary school teachers were conducted in schools which were selected by the inspectorate on the basis of advances they had made in educational technology use. Stimulated recall interviews - a verbal reporting technique in which the teachers were asked to verbalize their thoughts while looking at their own classroom practice on video - seemed to be a promising approach to increase authentic understandings of technology integration. The results emphasize that (a) the teachers involved in this study were pedagogically proficient and flexible enough to fit technology in with the varying demands of their educational practices, (b) the teachers\u27 ongoing learning experiences rather than training affected the development of the quality of their practices, and (c) the role of the school and the broader context of teachers\u27 personal lives played an important role. By interpreting the results of the study, recommendations are discussed for teacher technology integration and future research

    Quantum Hall induced currents and the magnetoresistance of a quantum point contact

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    We report an investigation of quantum Hall induced currents by simultaneous measurements of their magnetic moment and their effect on the conductance of a quantum point contact (QPC). Features in the magnetic moment and QPC resistance are correlated at Landau-level filling factors nu=1, 2 and 4, which demonstrates the common origin of the effects. Temperature and non-linear sweep rate dependences are observed to be similar for the two effects. Furthermore, features in the noise of the induced currents, caused by breakdown of the quantum Hall effect, are observed to have clear correlations between the two measurements. In contrast, there is a distinct difference in the way that the induced currents decay with time when the sweeping field halts at integer filling factor. We attribute this difference to the fact that, while both effects are sensitive to the magnitude of the induced current, the QPC resistance is also sensitive to the proximity of the current to the QPC split-gate. Although it is clearly demonstrated that induced currents affect the electrostatics of a QPC, the reverse effect, the QPC influencing the induced current, was not observed

    Prevalence of and Barriers to Dual-Contraceptive Methods Use among Married Men and Women Living with HIV in India

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    Objective. To describe the prevalence and correlates of dual-contraceptive methods use (condoms and an effective pregnancy prevention method) and barriers to their use among married persons living with HIV (PLHIV) in India. Methods. We conducted a quantitative survey (93 men, 97 women), 25 in-depth interviews, seven focus groups, and five key informant interviews. Results. Prevalence of dual- contraceptive method use increased from 5% before HIV diagnosis to 23% after diagnosis (P < 0.001). Condoms were the most common contraceptive method, with prevalence increasing from 13% before diagnosis to 92% after diagnosis (P < 0.001). Barriers to using noncondom contraceptives were lack of discussion about noncondom contraceptives by health care providers, lack of acceptability of noncondom contraceptives among PLHIV, and lack of involvement of husbands in family planning counseling. Conclusion. There is a need for interventions, including training of health care providers, to increase dual-contraceptive methods use among married PLHIV

    Gene Modification Strategies to Induce Tumor Immunity

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    The immune system provides an attractive option for use in cancer therapy. Our increasing understanding of the molecular events important in the generation of an effective immune response presents us with the opportunity to manipulate key genes to boost the immune response against cancer. Genetic modification is being employed to enhance a range of immune processes including antigen presentation, activation of specific T cells, and localization of immune effectors to tumors. In this review, we describe how many diverse cell types, including dendritic cells, T cells, and tumor cells, are being modified with a variety of genes, including those encoding antigens, cytokines, and chemokines, in order to enhance tumor immunity

    Meaning‐based coping, chronic conditions and quality of life in advanced cancer & caregiving

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    ObjectiveThis study examined the relationship between the number of co‐existing health problems (patient comorbidities and caregiver chronic conditions) and quality of life (QOL) among patients with advanced cancer and their caregivers and assessed the mediating and moderating role of meaning‐based coping on that relationship.MethodsData came from patients with advanced cancers (breast, colorectal, lung, and prostate) and their family caregivers (N = 484 dyads). Study hypotheses were examined with structural equation modeling using the actor‐partner interdependence mediation model. Bootstrapping and model constraints were used to test indirect effects suggested by the mediation models. An interaction term was added to the standard actor‐partner interdependence model to test for moderation effects.ResultsMore patient comorbidities were associated with lower patient QOL. More caregiver chronic conditions were associated with lower patient and caregiver QOL. Patient comorbidities and caregiver chronic conditions had a negative influence on caregiver meaning‐based coping but no significant influence on patient meaning based coping. Caregiver meaning‐based coping mediated relationships between patient comorbidities and caregiver health conditions and patient and caregiver QOL. No significant moderating effects were observed.ConclusionsDespite the severity of advanced cancer for patients and caregivers, the co‐existing health problems of one member of the dyad have the potential to directly or indirectly affect the wellbeing of the other. Future research should consider how the number of patient comorbidities and caregiver chronic conditions, as well as the ability of patients and caregivers to manage those conditions, influences their meaning‐based coping and wellbeing. Copyright © 2016 John Wiley & Sons, Ltd.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138410/1/pon4146_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138410/2/pon4146.pd
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