65 research outputs found

    Poetic development of Hugh MacDiarmid (Christopher Murray Grieve) : 1923-34

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    SIGLEAvailable from British Library Document Supply Centre- DSC:D38975/82 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Thinking like a student: subject guides in small academic libraries

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    Small academic libraries still need to produce web-based subject guides despite limited budgets. This practical communication describes how one such library in Australia used freely available wiki software and third-party hosting to create a web-based set of subject guides and a subsequent redesign based around typical student tasks. It demonstrates that it is possible to produce high quality guides that meet student needs with minimal costs

    Thinking like a student: subject guides in small academic libraries

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    Small academic libraries still need to produce web-based subject guides despite limited budgets. This practical communication describes how one such library in Australia used freely available wiki software and third-party hosting to create a web-based set of subject guides and a subsequent redesign based around typical student tasks. It demonstrates that it is possible to produce high quality guides that meet student needs with minimal costs

    Is it a library or is it art?

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    The Future Library. The Library of Unborrowed Books. The Reanimation Library. A Library of Approximate Location. These are not typical names for libraries but they are tantalising and they are real. Each of these libraries has been created by an artist and they are not the only ones. These libraries function both as libraries and as art installations and can be temporary exhibitions or permanent installations. Some are recognisably libraries and others are not. Some are tied to a specific place and others are peripatetic. They are scattered around the globe and, as well as investigating artistic themes of time, loss, place and memory, consider the library as subject as well as object. As such, they raise interesting questions for librarians. What does the library symbolise for the artist and the audience? What are the motivations of the artists involved? What purposes do these libraries aim to achieve? What does it mean for the artist to become the librarian? What are the implications for us as librarians? What can we learn from these artist libraries? This paper will explore these questions and attempt some preliminary answers

    Concerted functions of<i> Streptococcus gordonii</i> surface proteins PadA and Hsa mediate activation of human platelets and interactions with extracellular matrix

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    A range of Streptococcus bacteria are able to interact with blood platelets to form a thrombus (clot). Streptococcus gordonii is ubiquitous within the human oral cavity and amongst the common pathogens isolated from subjects with infective endocarditis. Two cell surface proteins, Hsa and Platelet adherence protein A (PadA), in S. gordonii mediate adherence and activation of platelets. In this study, we demonstrate that PadA binds activated platelets and that an NGR (Asparagine-Glycine-Arginine) motif within a 657 amino acid residue N-terminal fragment of PadA is responsible for this, together with two other integrin-like recognition motifs RGT and AGD. PadA also acts in concert with Hsa to mediate binding of S. gordonii to cellular fibronectin and vitronectin, and to promote formation of biofilms. Evidence is presented that PadA and Hsa are each reliant on the other\u27s active presentation on the bacterial cell surface, suggesting cooperativity in functions impacting both colonization and pathogenesis

    Videographic criticism as research and exhibition artefact

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    This article builds upon Susan Kerrigan’s model for a scale and magnitude approach to creativity (Kerrigan, Susan. 2019b. “Filmmaking as Creative Practice: Assessing Creative Magnitude and Scale.” Global Media Journal: Australian Edition 13 (1): 1–11. https://www.hca.westernsydney.edu.au/gmjau/?p=2941),by considering the addition of academic exhibition as a means to increase magnitude. Building from Kauffman and Beghetto’s model of creativity (Kaufman, James C., and Ronald A. Beghetto. 2009. “Beyond Big and Little: The Four C Model of Creativity.” Review of General Psychology 13 (1): 1–12. doi:10.1037/a0013688) this article introduces transitional limits to facilitate for creative practitioners working within the little-c and Pro-c criteria but are not yet eminent. In doing so, it problematises the idea of what constitutes professional and raises the question of how might a student or professional researcher escape the definition of little-c by increasing their magnitude? To consider this question, this article uses three primary case studies to explore how postgraduate researchers and professional academics are working at the Pro-c level, by situating them within the Four C model. Finally, considering how we can use videographic criticism as an ancillary product of research practice that can increase student and professional scholar’s creative magnitude, under the principle of forward incrementation (2009, 5)

    The history of falls and the association of the timed up and go test to falls and near-falls in older adults with hip osteoarthritis

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    Abstract Background Falling accounts for a significant number of hospital and long-term care admissions in older adults. Many adults with the combination of advancing age and functional decline associated with lower extremity osteoarthritis (OA), are at an even greater risk. The purpose of this study was to describe fall and near-fall history, location, circumstances and injuries from falls in a community-dwelling population of adults over aged 65 with hip OA and to determine the ability of the timed up and go test (TUG) to classify fallers and near-fallers. Method A retrospective observational study of 106 older men and women with hip pain for six months or longer, meeting a clinical criteria for the presence of hip OA at one or both hips. An interview for fall and near-fall history and administration of the TUG were administered on one occasion. Results Forty-five percent of the sample had at least one fall in the past year, seventy-seven percent reported occasional or frequent near-falls. The majority of falls occurred during ambulation and ascending or descending steps. Forty percent experienced an injury from the fall. The TUG was not associated with history of falls, but was associated with near-falls. Higher TUG scores occurred for those who were older, less mobile, and with greater number of co-morbidities. Conclusion A high percentage of older adults with hip OA experience falls and near-falls which may be attributed to gait impairments related to hip OA. The TUG could be a useful screening instrument to predict those who have frequent near-falls, and thus might be useful in predicting risk of future falls in this population.</p

    Lives saved by Global Fund-supported HIV/AIDS, tuberculosis and malaria programs: estimation approach and results between 2003 and end-2007

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    <p>Abstract</p> <p>Background</p> <p>Since 2003, the Global Fund has supported the scale-up of HIV/AIDS, tuberculosis and malaria control in low- and middle-income countries. This paper presents and discusses a methodology for estimating the lives saved through selected service deliveries reported to the Global Fund.</p> <p>Methods</p> <p>Global Fund-supported programs reported, by end-2007, 1.4 million HIV-infected persons on antiretroviral treatment (ARV), 3.3 million new smear-positive tuberculosis cases detected in DOTS (directly observed TB treatment, short course) programs, and 46 million insecticide-treated mosquito nets (ITNs) delivered. We estimated the corresponding lives saved using adaptations of existing epidemiological estimation models.</p> <p>Results</p> <p>By end-2007, an estimated 681,000 lives (95% uncertainty range 619,000-774,000) were saved and 1,097,000 (993,000-1,249,000) life-years gained by ARV. DOTS treatment would have saved 1.63 million lives (1.09 - 2.17 million) when compared against no treatment, or 408,000 lives (265,000-551,000) when compared against non-DOTS treatment. ITN distributions in countries with stable endemic <it>falciparum </it>malaria were estimated to have achieved protection from malaria for 26 million of child-years at risk cumulatively, resulting in 130,000 (27,000-232,000) under-5 deaths prevented.</p> <p>Conclusions</p> <p>These results illustrate the scale of mortality effects that supported programs may have achieved in recent years, despite margins of uncertainty and covering only selected intervention components. Evidence-based evaluation of disease impact of the programs supported by the Global Fund with international and in-country partners must be strengthened using population-level data on intervention coverage and demographic outcomes, information on quality of services, and trends in disease burdens recorded in national health information systems.</p

    Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution.

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    Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. However, their genetic diversity is considerable, and although sixty-two genomes have been sequenced and comparatively analyzed, these likely represent only a small portion of the diversity of the mycobacteriophage population at large. Here we report the isolation, sequencing and comparative genomic analysis of 18 new mycobacteriophages isolated from geographically distinct locations within the United States. Although no clear correlation between location and genome type can be discerned, these genomes expand our knowledge of mycobacteriophage diversity and enhance our understanding of the roles of mobile elements in viral evolution. Expansion of the number of mycobacteriophages grouped within Cluster A provides insights into the basis of immune specificity in these temperate phages, and we also describe a novel example of apparent immunity theft. The isolation and genomic analysis of bacteriophages by freshman college students provides an example of an authentic research experience for novice scientists
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