Turbo décodage de code produit haut débit utilisant un code BCH étendu (128,106,8) t=3

- Cet article propose une nouvelle architecture de turbo décodage de codes BCH (128,106,8) à entrées et sorties pondérées corrigeant 3 erreurs. En utilisant le concept de parallélisme et les propriétés de la matrice générée par un code produit, cet article présente la conception et la complexité de trois décodeurs capables de traiter 2, 4 et 8 données en même temps pour obtenir le haut débit dans le décodage. Pour comparer les performances et la complexité entre les différents décodeurs, le langage C a été utilisé pour les simulations, le langage VHDL pour les simulations fonctionnelles et Synopsys Design Compiler pour la synthèse. Les résultats ainsi obtenus ouvrent la possibilité d'intégration sur le silicium de turbo décodeurs à fort pouvoir de correction (distance de 64, rendement de 0,8) et à haut débit (6,4Gbits/s)

Carbohydrate-active enzymes from <em>Akkermansia</em> <em>muciniphila</em> break down mucin <em>O</em>-glycans to completion

\ua9 The Author(s) 2025. Akkermansia muciniphila is a human microbial symbiont residing in the mucosal layer of the large intestine. Its main carbon source is the highly heterogeneous mucin glycoprotein, and it uses an array of carbohydrate-active enzymes and sulfatases to access this complex energy source. Here we describe the biochemical characterization of 54 glycoside hydrolases, 11 sulfatases and 1 polysaccharide lyase from A. muciniphila to provide a holistic understanding of their carbohydrate-degrading activities. This was achieved using a variety of liquid chromatography techniques, mass spectrometry, enzyme kinetics and thin-layer chromatography. These results are supported with A. muciniphila growth and whole-cell assays. We find that these enzymes can act synergistically to degrade the O-glycans on the mucin polypeptide to completion, down to the core N-acetylgalactosaime. In addition, these enzymes can break down human breast milk oligosaccharide, ganglioside and globoside glycan structures, showing their capacity to target a variety of host glycans. These data provide a resource to understand the full degradative capability of the gut microbiome member A. muciniphila

Implantation d'un récepteur multi-utilisateurs appliqué à la liaison UMTS

Cet article présente les étapes préparatoires à l'implantation d'un récepteur multi-utilisateurs appliqué à la liaison montante du système UMTS. Tout d'abord, la comparaison des résultats des simulations d'une détection mono-utilisateur à base de Filtre Adapté avec une détection multi-utilisateurs à suppression d'interférence successive (SIC) dans le cas synchrone permet de valider les choix faits. Puis dans un contexte asynchrone à trajets multiples, il est possible de comparer les performances d'un récepteur RAKE à celles d'un récepteur SIC/RAKE. Les simulations sont faites avec un traitement à valeur réelle d'une part et à valeur entière d'autre part pour permettre l'étude et l'optimisation de la quantification

Mother-to-child transmission of human T-cell lymphotropic virus types I and II (HTLV-I/II) in Gabon: a prospective follow-up of 4 years

For 4 years, we determined the mode and risk of mother-to-child transmission of HTLV-I in a prospective cohort of 34 children born to seropositive mothers in Franceville, Gabon. We also determined the prevalence of antibodies to HTLV-I/II in siblings born to seropositive mothers. Antibodies to HTLV-I/II were detected by Western blot, and the proviral DNA was detected by the polymerase chain reaction (PCR). The risk of seroconversion to anti-HTLV-I for the 4 years of follow-yp was 17.5 %. Anti-HTLV-I/II and proviral DNA were only detected after age 18 months. We observed a seroprevalence rate of 15 % among the siblings born to HTLV-I/II seropositive mothers. Furthermore, we report a case of mother-to-child transmission of HTLV-II infection in a population of HTLV-II-infected pregnant women that is emerging in Gabon. The lack of detection of HTLV-I/II proviral DNA in cord blood and amniotic fluid and, furthermore, the late seroconversion observed in the children indirectly indicate that mother-to-child transmission occured postnatally, probably through breast milk. (Résumé d'auteur

Eco-Phoques : Bases scientifiques pour une meilleure connaissance des phoques et de leurs interactions avec les activités humaines en Manche Nord-Est: Rapport final pour la région Hauts-de-France et l’AFB.

Two seal species are found year-round in the Région Hauts-de-France (North of France): the harbour seal (Phoca vitulina), observed for decades in the area and still increasing, and the grey seal (Halicheorus grypus), more recently settled, which numbers have increased exponentially this last decade. While harbour seals are observed at all seasons and seem to be very faithful to their haulout sites, grey seals, mostly adult males, are mainly abundant in the area seasonally (during summer). More harbour seals are also counted on their haulout sites during summer, but this is most likely only due to their spending more time ashore during the breeding and moulting seasons. The maximum number of seals simultaneously censused on the haulout sites from baie de Somme to Dunkerque was 709 harbour seals in July 2017, and 402 grey seals in July 2016. These maxima increased these last years, even if in some haulout areas the yearly maximum counts remain stable since 2015. Telemetry tracking showed that harbour seals from the baie de Somme make very coastal movements, and forage mostly in front of (or close vicinity, a few kilometres away from) the baie de Somme. They can travel over a few tens or a hundred of kilometres, sometimes moving from one colony to another, as also shown by photo-identification matching between the baie d’Authie and baie de Canche. However, telemetry showed that grey seals move at a much larger scale, travelling over tens and hundreds of kilometres, foraging in the middle of the English Channel, in baie de Somme or along the coasts of Hauts-de-France, sometimes further in the North Sea where they return for breeding. Photo-identification also highlighted individual movements between baie de Somme, baie d’Authie and phare de Walde. This technique showed that seals from both species were faithful to their haulout sites. This site fidelity was higher in harbour seals, but a significant proportion of grey seals also came back from one year to the next. The haulout site at phare de Walde seems to be a step-over area for grey seals (from the Southern North Sea), with more photoidentified individuals observed only once. The seals’ diet, estimated from faeces sampled in baie de Somme (and also Walde for grey seals) consisted of 86% [95% confidence interval: 68-100%, in biomass] of flat fish and 14% [5-25%] of round fish for harbour seals, and of 61% [38-87%] of flat fish, 29% [13-54%] of round fish and 10% [1-23%] of cephalopods for grey seals. In both seal species, flat fish species were mainly plaice, flounder or different sole species, and the main round fish species in grey seals was herring. Additional diet analysis from stomach samples of stranded seals suggested that cephalopods may be underestimated in the grey seal diet especially. Trophic overlap between both seal species was high, but a higher inter-individual variability was observed in grey seals, considered as individual specialists, than in harbour seals, rather considered as specialized at the colony level. The analysis of ecological tracers (carbon and nitrogen stable isotopes) showed that results of seal diet obtained exclusively in baie de Somme cannot always be generalized to the whole region, and that the trophic niche of harbour seals was included in that of grey seals. All these results (on diet and tracers) suggest interactions between both species, and potentially competition, that could evolve in the future if grey seal numbers continue to grow. From 2015 to 2017, total prey consumption by seals from baie de Somme and baie d’Authie increased from 592 [490-701] to 750 [632-878] tons per year for harbour seals and from 422 [369-476] to 750 [675-827] tons per year for grey seals. Seasonal variations in total consumption were limited for harbour seals, but larger for grey seals, mostly abundant in the area during summer. During this summer season, their prey consumption most likely exceeds that of harbour seals. Both seal species are strongly interacting with each other, but less so with fishery activities, except for trammelers for which the fishing effort strongly overlaps with harbour seal foraging areas (overlap 18 times higher between trammelers and harbour seals than between all fishing gear and harbour seals). Sport and tourism activities also cause interactions with seals, that are either seen as positive (e.g. seals attract tourism, contribute to the regional identity…) or negative (risks of disturbance of the seals). Users along the coast are conscious of these interactions, and it seems necessary to maintain the existing monitoring in order to better evaluate those interactions, in a context of increasing seal populations