Stellar Velocity Dispersion of the Leo A Dwarf Galaxy

We measure the first stellar velocity dispersion of the Leo A dwarf galaxy, \sigma = 9.3 +- 1.3 km/s. We derive the velocity dispersion from the radial velocities of ten young B supergiants and two HII regions in the central region of Leo A. We estimate a projected mass of 8 +- 2.7 x10^7 solar masses within a radius of 2 arcmin, and a mass to light ratio of at least 20 +- 6 M_sun/L_sun. These results imply Leo A is at least ~80% dark matter by mass.Comment: 6 pages, accepted to Ap

The TAOS Project: Upper Bounds on the Population of Small KBOs and Tests of Models of Formation and Evolution of the Outer Solar System

We have analyzed the first 3.75 years of data from TAOS, the Taiwanese American Occultation Survey. TAOS monitors bright stars to search for occultations by Kuiper Belt Objects (KBOs). This dataset comprises 5e5 star-hours of multi-telescope photometric data taken at 4 or 5 Hz. No events consistent with KBO occultations were found in this dataset. We compute the number of events expected for the Kuiper Belt formation and evolution models of Pan & Sari (2005), Kenyon & Bromley (2004), Benavidez & Campo Bagatin (2009), and Fraser (2009). A comparison with the upper limits we derive from our data constrains the parameter space of these models. This is the first detailed comparison of models of the KBO size distribution with data from an occultation survey. Our results suggest that the KBO population is comprised of objects with low internal strength and that planetary migration played a role in the shaping of the size distribution.Comment: 18 pages, 16 figures, Aj submitte

Circumbinary Chaos: Using Pluto's Newest Moon to Constrain the Masses of Nix & Hydra

The Pluto system provides a unique local laboratory for the study of binaries with multiple low mass companions. In this paper, we study the orbital stability of P4, the most recently discovered moon in the Pluto system. This newfound companion orbits near the plane of the Pluto-Charon binary, roughly halfway between the two minor moons Nix and Hydra. We use a suite of few body integrations to constrain the masses of Nix and Hydra, and the orbital parameters of P4. For the system to remain stable over the age of the Solar System, the masses of Nix and Hydra likely do not exceed 5e16 kg and 9e16 kg, respectively. These upper limits assume a fixed mass ratio between Nix and Hydra at the value implied by their median optical brightness. Our study finds that stability is more sensitive to their total mass and that a downward revision of Charon's eccentricity (from our adopted value of 0.0035) is unlikely to significantly affect our conclusions. Our upper limits are an order of magnitude below existing astrometric limits on the masses of Nix and Hydra. For a density at least that of ice, the albedos of Nix and Hydra would exceed 0.3. This constraint implies they are icy, as predicted by giant impact models. Even with these low masses, P4 only remains stable if its eccentricity e < 0.02. The 5:1 commensurability with Charon is particularly unstable, Combining stability constraints with the observed mean motion places the preferred orbit for P4 just exterior to the 5:1 resonance. These predictions will be tested when the New Horizons satellite visits Pluto. Based on the results for the Pluto-Charon system, we expect that circumbinary, multi-planet systems will be more widely spaced than their singleton counterparts. Further, circumbinary exoplanets close to the three-body stability boundary, such as those found by Kepler, are less likely to have other companions nearby.Comment: 12 pages, 7 figure

Collisional Cascades in Planetesimal Disks II. Embedded Planets

We use a multiannulus planetesimal accretion code to investigate the growth of icy planets in the outer regions of a planetesimal disk. In a quiescent minimum mass solar nebula, icy planets grow to sizes of 1000--3000 km on a timescale t = 15-20 Myr (a/30 AU)^3 where a is the distance from the central star. Planets form faster in more massive nebulae. Newly-formed planets stir up leftover planetesimals along their orbits and produce a collisional cascade where icy planetesimals are slowly ground to dust. The dusty debris of planet formation has physical characteristics similar to those observed in beta Pic, HR 4796A, and other debris disks. We derive dust masses for small particles, 1 mm and smaller, and large particles, 1 mm and larger, as a function of the initial conditions in the planetesimal disk. The dust luminosities derived from these masses are similar to those observed in Vega, HR 4796A, and other debris disks. The calculations produce bright rings and dark gaps. Bright rings occur where 1000 km and larger planets have recently formed. Dark gaps are regions where planets have cleared out dust or shadows where planets have yet to form.Comment: to be published in the Astronomical Journal, January 2004; 7 pages of text; 17 figures at http://cfa-www.harvard.edu/~kenyon/pf/emb-planet-figures.pdf; 2 animations at http://cfa-www.harvard.edu/~kenyon/pf/emb-planet-movies.htm

Resident Corneal Cells Communicate with Neutrophils Leading to the Production of IP-10 during the Primary Inflammatory Response to HSV-1 Infection

In this study we show that murine and human neutrophils are capable of secreting IP-10 in response to communication from the HSV-1 infected cornea and that they do so in a time frame associated with the recruitment of CD8+ T cells and CXCR3-expressing cells. Cellular markers were used to establish that neutrophil influx corresponded in time to peak IP-10 production, and cellular depletion confirmed neutrophils to be a significant source of IP-10 during HSV-1 corneal infection in mice. A novel ex vivo model for human corneal tissue infection with HSV-1 was used to confirm that cells resident in the cornea are also capable of stimulating neutrophils to secrete IP-10. Our results support the hypothesis that neutrophils play a key role in T-cell recruitment and control of viral replication during HSV-1 corneal infection through the production of the T-cell recruiting chemokine IP-10

Design and Benchmark Testing for Open Architecture Reconfigurable Mobile Spirometer and Exhaled Breath Monitor with GPS and Data Telemetry.

Portable and wearable medical instruments are poised to play an increasingly important role in health monitoring. Mobile spirometers are available commercially, and are used to monitor patients with advanced lung disease. However, these commercial monitors have a fixed product architecture determined by the manufacturer, and researchers cannot easily experiment with new configurations or add additional novel sensors over time. Spirometry combined with exhaled breath metabolite monitoring has the potential to transform healthcare and improve clinical management strategies. This research provides an updated design and benchmark testing for a flexible, portable, open access architecture to measure lung function, using common Arduino/Android microcontroller technologies. To demonstrate the feasibility and the proof-of-concept of this easily-adaptable platform technology, we had 43 subjects (healthy, and those with lung diseases) perform three spirometry maneuvers using our reconfigurable device and an office-based commercial spirometer. We found that our system compared favorably with the traditional spirometer, with high accuracy and agreement for forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC), and gas measurements were feasible. This provides an adaptable/reconfigurable open access "personalized medicine" platform for researchers and patients, and new chemical sensors and other modular instrumentation can extend the flexibility of the device in the future

Vacancy localization in the square dimer model

We study the classical dimer model on a square lattice with a single vacancy by developing a graph-theoretic classification of the set of all configurations which extends the spanning tree formulation of close-packed dimers. With this formalism, we can address the question of the possible motion of the vacancy induced by dimer slidings. We find a probability 57/4-10Sqrt[2] for the vacancy to be strictly jammed in an infinite system. More generally, the size distribution of the domain accessible to the vacancy is characterized by a power law decay with exponent 9/8. On a finite system, the probability that a vacancy in the bulk can reach the boundary falls off as a power law of the system size with exponent 1/4. The resultant weak localization of vacancies still allows for unbounded diffusion, characterized by a diffusion exponent that we relate to that of diffusion on spanning trees. We also implement numerical simulations of the model with both free and periodic boundary conditions.Comment: 35 pages, 24 figures. Improved version with one added figure (figure 9), a shift s->s+1 in the definition of the tree size, and minor correction

Accretion in the Early Kuiper Belt II. Fragmentation

We describe new planetesimal accretion calculations in the Kuiper Belt that include fragmentation and velocity evolution. All models produce two power law cumulative size distributions, N_C propto r^{-q}, with q = 2.5 for radii less than 0.3-3 km and q = 3 for radii exceeding 1-3 km. The power law indices are nearly independent of the initial mass in the annulus, the initial eccentricity of the planetesimal swarm, and the initial size distribution of the planetesimal swarm. The transition between the two power laws moves to larger radii as the initial eccentricity increases. The maximum size of objects depends on their intrinsic tensile strength; Pluto formation requires a strength exceeding 300 erg per gram. Our models yield formation timescales for Pluto-sized objects of 30-40 Myr for a minimum mass solar nebula. The production of several `Plutos' and more than 10^5 50 km radius Kuiper Belt objects leaves most of the initial mass in 0.1-10 km radius objects that can be collisionally depleted over the age of the solar system. These results resolve the puzzle of large Kuiper Belt objects in a small mass Kuiper Belt.Comment: to appear in the Astronomical Journal (July 1999); 54 pages including 7 tables and 13 figure

The Rise and Fall of Debris Disks: MIPS Observations of h and chi Persei and the Evolution of Mid-IR Emission from Planet Formation

We describe Spitzer/MIPS observations of the double cluster, h and $\chi$ Persei, covering a $\sim$ 0.6 square-degree area surrounding the cores of both clusters. The data are combined with IRAC and 2MASS data to investigate $\sim$ 616 sources from 1.25-24 $\mu m$. We use the long-baseline $K_{s}$-[24] color to identify two populations with IR excess indicative of circumstellar material: Be stars with 24 $\mu m$ excess from optically-thin free free emission and 17 fainter sources (J$\sim$ 14-15) with [24] excess consistent with a circumstellar disk. The frequency of IR excess for the fainter sources increases from 4.5 $\mu m$ through 24 $\mu m$. The IR excess is likely due to debris from the planet formation process. The wavelength-dependent behavior is consistent with an inside-out clearing of circumstellar disks. A comparison of the 24 $\mu m$ excess population in h and $\chi$ Per sources with results for other clusters shows that 24 $\mu m$ emission from debris disks 'rises' from 5 to 10 Myr, peaks at $\sim$ 10-15 Myr, and then 'falls' from $\sim$ 15/20 Myr to 1 Gyr.Comment: 48 pages, 15 figures, accepted for publication in The Astrophysical Journa

First Results From The Taiwanese-American Occultation Survey (TAOS)

Results from the first two years of data from the Taiwanese-American Occultation Survey (TAOS) are presented. Stars have been monitored photometrically at 4 Hz or 5 Hz to search for occultations by small (~3 km) Kuiper Belt Objects (KBOs). No statistically significant events were found, allowing us to present an upper bound to the size distribution of KBOs with diameters 0.5 km < D < 28 km.Comment: 5 pages, 5 figure, accepted in Ap