3,845 research outputs found

    Child Poverty in Rural America

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    This report explores the well-being of the 14 million children who live in rural America. Rural families represent a significant share of our total population and they are disproportionately poor, less educated, and underemployed. Yet poor children and the unique challenges they face are often overlooked by policymakers. Poor children living in rural America face significant educational, social, and economic challenges just as their urban counterparts do, but many of these problems are exacerbated by the isolation and limited access to support services common in rural areas

    Discussant\u27s response to an examination of the status of probability sampling in the courts

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    https://egrove.olemiss.edu/dl_proceedings/1178/thumbnail.jp

    More poor kids in more poor places: children increasingly live where poverty persists

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    More poor kids in more poor places: children increasingly live where poverty persist

    Risks vs benefits of glatiramer acetate: a changing perspective as new therapies emerge for multiple sclerosis

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    An understanding of the risks, benefits, and relative value of glatiramer acetate (GA) in multiple sclerosis (MS) has been evolving based on recently completed head-to-head studies: REGARD (REbif vs Glatiramer Acetate in Relapsing MS Disease); BEYOND (Betaseron Efficacy Yielding Outcomes of a New Dose); and BECOME (BEtaseron vs COpaxone in Multiple Sclerosis with Triple-Dose Gadolinium and 3-Tesla MRI Endpoints). Outcomes in the primary endpoints of these trials showed no significant differences between GA and high-dose beta-interferons (IFNβs). Results of the PreCISe (Early GA Treatment in Delaying Conversion to Clinically Definite Multiple Sclerosis [CDMS] in Subjects Presenting With a Clinically Isolated Syndrome [CIS]) trial led to the US Food and Drug Administration approval of GA in patients with a CIS. Furthermore, the ongoing follow-up study to the original pivotal GA trial, now extending beyond 15 years, continues to support the safety of GA. Currently, GA and IFNβs are no longer the only immunomodulators available for MS. Introduction of the monoclonal antibody, natalizumab (Tysabri®; Biogen Idec, Inc., Cambridge, MA, USA) provides an alternative immunomodulator for MS and has changed the therapeutic landscape dramatically. However, the rare but serious cases of progressive multifocal leukoencephalopathy that have occurred with natalizumab have raised concerns among clinicians and patients about using this agent and some of the emerging agents. The potential risks and benefits of the emerging therapies (cladribine, alemtuzumab, rituximab, fingolimod, laquinimod, teriflunomide, and dimethyl fumarate) based on phase II/III trials, as well as their use for indications other than MS, will be presented. This review provides available data on GA, natalizumab, and the emerging agents to support new developments in our understanding of GA and how its long-standing role as a first-line therapy in MS will evolve within the increasingly complex MS therapeutic landscape

    Fitting segmented regression curves

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    Population, Greenspace, and Development:Conversion Patterns in the Great Lakes Region

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    In this brief, authors Mark Ducey, Kenneth Johnson, Ethan Belair, and Barbara Cook combine demographic, land-cover, and other spatial data to estimate the incidence and extent of conversion from greenspace (forestland, shrublands, and grasslands) to development in the Great Lakes states. They report that greenspace conversions to developed land are most common in areas where greenspace is already limited. Population density strongly influences the conversion of greenspace to development. Conversions are most likely to occur on the urban periphery and in high-amenity rural areas. This research contributes to a better understanding of the linkages between demographic and land-cover change and provides facts that can inform policy aimed at balancing development and greenspace conservation

    Forests in Flux: The Effects of Demographic Change on Forest Cover in New England and New York

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    This brief contributes to a better understanding of the linkages between demographic and forest cover change so as to inform policy efforts aimed at maintaining existing forested areas in and around sprawling urban centers. Authors Mark Ducey, Kenneth Johnson, Ethan Belair, and Miranda Mockrin report that forest cover has declined throughout New England and New York over the last decade. In rural areas, forest loss is primarily due to commercial timber harvesting and represents a temporary change. Conversely, forest cover decline in urban areas is usually the result of development and is likely to be permanent. Forest cover change is strongly linked to demographic variables throughout this region. Forest cover loss is most pronounced along the urban fringe, where population growth is greatest. Amenity-rich rural areas are also experiencing high rates of population growth and regionally-high rates of forest cover loss. However, the causes of forest cover change in these areas are less certain. Forest cover change has the potential to impact ecosystem services important to both local residents and the larger region

    The Increasing Diversity of America\u27s Youth

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    This brief documents how unfolding demographic forces have placed today’s children and youth at the forefront of America’s new racial and ethnic diversity. Authors Kenneth M. Johnson, Andrew Schaefer, Daniel T. Lichter, and Luke T. Rogers discuss how the rapidly changing racial and ethnic composition of the youth population has important implications for intergroup relations, ethnic identities, and electoral politics. They report that diversity is increasing among America’s youth because there are more minority children and fewer non-Hispanic white children. Minority births exceeded non-Hispanic white births for the first time in U.S. history in 2011 according to Census Bureau estimates. Both the declining number of non-Hispanic white women of prime child-bearing and growing numbers of minority women contributed to this change as did differential fertility rates. The largest gains in child diversity between 2000 and 2012 were in suburban and smaller metropolitan areas. Yet, child diversity is geographically uneven, with minimal diversity in some areas of the country and significant diversity in other areas. They conclude that natural population increase—particularly fertility rates—will continue to reshape the racial and ethnic mix of the country, and this change will be reflected first among the nation’s youngest residents

    Protein and Lysine Content of Grain, Endosperm, and Bran of Wheats from the USDA World Wheat Collection

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    The effects of relative amounts and the protein and lysine concentrations of kernel components on whole grain protein and lysine in wheat (Triticum aestivum L.) were studied. Wheats from the USDA World Wheat Collection that differed in whole grain protein and lysine content were compared. The correlation of grain protein with endosperm protein was r = 0.98, showing that whole grain protein percentages accurately reflect endosperm protein content in wheat. The correlation of grain and endosperm lysine percentages was lower. Endosperm percent protein had the largest effect on grain lysine content of any of the factors tested. The combined effect of percent of bran, bran percent protein, and bran lysine (% of protein) on whole grain lysine content was great as the effect of endosperm lysine (% of protein). Wheats with high grain lysine content do not always have high endosperm lyslne content. Differences were detected among the wheats studied for endosperm and bran protein and lysine content

    Protein and Lysine Contents of Endosperm and Bran of the Parents and Progenies of Crosses of Common Wheat

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    Grain samples from parent and progeny rows of the common wheat (Triticum aestivum L.) crosses, \u27Nap Hal\u27/ \u27Atlas 66* and Nap Hal/\u27Super X\u27, were fractionated into their starchy endosperm and bran components to determine the within-kernel site of their variation in protein and lysine concentration. Nap Hal and Atlas 66 are highprotein wheats. Nap Hal also has elevated grain lysine content. Super X has average protein and lysine content. Transgressive segregation existed both for high and low endosperm protein concentration among the F3 progeny rows of Nap Hal/Atlas 66. Low-protein progeny rows had endosperm protein percentages that were 3 to 5 percentage points lower than the parental mean (19.5%). High-protein progeny lines were 2 to 4 percentage points higher than the parental mean. Nap Hal and some of the progeny rows were 5 percentage points higher in bran protein content than Atlas 66. Endosperm and bran protein percentages of Nap Hal/Super X F4 progeny were within the parental range. Some progeny rows had endosperm and bran protein concentrations equal to those of Nap Hal. Variation among the progeny rows for endosperm and bran lysine (% of protein) concentrations was within the range of variability of the replicated parental rows. Variation for grain protein content among the progeny rows of both crosses was due to variation for both endosperm and bran protein content. Variation for grain lysine (% of sample) among the Nap Hal/Atlas 66 progeny rows was due primarily to variation in endosperm and bran protein content with endosperm and bran lysine (% of protein) being of lesser importance
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