4,706 research outputs found
Integration of CSAB and ABET
The Accreditation Board for Engineering and Technology, Inc. (ABET) and the Computing Sciences Accreditation Board (CSAB) signed a Memorandum of Agreement in November 1998 to integrate CSAB\u27\u27s accreditation services with ABET, with a transition time of approximately two years. During the interim period, the operations of the Computer Science Accreditation Commission (CSAC) are contracted by CSAB to ABET. A committee with CSAC, CSAB, and ABET representation is working to set up the new commission for accrediting programs in the computing sciences. This new commission will probably be called the Computing Accreditation Commission (CAC). Other activities are underway to try to assure that this integration goes as smoothly as possible. This paper discusses from various points of view the current status of the integration and plans for the completion of the integration
Spectrometer Scan Mechanism for Encountering Jovian Orbit Trojan Asteroids
This paper describes the design, testing, and lessons learned during the development of the Lucy Ralph (L'Ralph) Scan Mirror System (SMS), composed of the Scan Mirror Mechanism (SMM), Differential Position Sensor System (DPSS) and Mechanism Control Electronics (MCE). The L'Ralph SMS evolved from the Advanced Topographic Laser Altimeter System (ATLAS) Beam Steering Mechanism (BSM), so design comparisons will be made. Lucy is scheduled to launch in October 2021, embarking upon a 12-year mission to make close range encounters in 2025 and 2033 with seven Trojan asteroids and one main belt asteroid that are within the Jovian orbit. The L'Ralph instrument is based upon the New Horizons Ralph instrument, which is a panchromatic and color visible imager and infrared spectroscopic mapper that slewed the spacecraft for imaging. The L'Ralph SMM is to provide scanning for imaging to eliminate the need to slew the spacecraft. One purpose of this paper is to gain understanding of the reasoning behind some of the design features as compared with the ATLAS BSM. We will identify similarities and differences between the ATLAS BSM and the L'Ralph SMM that resulted from the latter's unique requirements. Another purpose of this paper is to focus upon "Lessons Learned" that came about during the development of the L'Ralph SMM and its MCE, both mechanism engineering issues and solutions as well as Ground Support Equipment (GSE) issues and solutions that came about during the validation of requirements process. At the time of this writing, the L'Ralph SMM has been flight qualified and delivered to the project
Neurocognitive Monitoring and Care During Pediatric Cardiopulmonary Bypass—Current and Future Directions
Neurologic injury in patients with congenital heart disease remains an important source of morbidity and mortality. Advances in surgical repair and perioperative management have resulted in longer life expectancies for these patients. Current practice and research must focus on identifying treatable risk factors for neurocognitive dysfunction, advancing methods for perioperative neuromonitoring, and refining treatment and care of the congenital heart patient with potential neurologic injury. Techniques for neuromonitoring and future directions will be discussed
Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes
Spinocerebellar ataxia (SCA) is a physically devastating, genetically inherited disorder characterized by abnormal brain function that results in the progressive loss of the ability to coordinate movements. There are many types of SCAs as there are various gene mutations that can cause this disease. SCA types 1–3, 6–10, 12, and 17 result from a trinucleotide repeat expansion in the DNA-coding sequence. Intriguingly, recent work has demonstrated that increased trinucleotde expansions in the SCA7 gene result in defect in the function of the SAGA histone acetyltransferase complex. The SCA7 gene encodes a subunit of the SAGA complex. This subunit is conserved in yeast as the SGF73 gene. We demonstrate that Sgf73 is required to recruit the histone deubiquitination module into both SAGA and the related SliK(SALSA) complex, and to maintain levels of histone ubiquitination, which is necessary for regulation of transcription at a number of genes
Flexural Cracks in Fiber-Reinforced Concrete Beams with Fiber-Reinforced Polymer Reinforcing Bars
Fiber-reinforced polymer (FRP) reinforcing bars have attracted considerable attention for applications where corrosion of steel reinforcement is problematic. Due to the generally low elastic modulus and poor bond characteristics of FRP as compared to steel reinforcing bars, the use of FRP results in larger crack widths under service loads. Fiber-reinforced concrete (FRC) is proposed for use with FRP to reduce crack widths. The work presented herein includes the results from 16 beams tested under four-point bending with either Grade 420 (Grade 60) steel or FRP reinforcing bars, and either plain concrete or FRC. A modified Gergely-Lutz model was applied to the measured crack widths to calculate bond coefficients that were used to quantify the effectiveness of FRC in reducing crack widths. In the beams with steel reinforcing bars, the FRC was found to have little influence on crack widths. In the beams with FRP reinforcing bars, the FRC was found to significantly reduce maximum crack widths
Atmospheric water balance
Submitted to Office of Water Resources Research, U.S. Department of Interior.Includes bibliographical references.OWRR project no. B-035-COLO
Chloroplast DNA and Nuclear DNA Content Variations among Cultivars of Switchgrass, \u3ci\u3ePanicum virgatum\u3c/i\u3e L.
Switchgrass, Panicum virgatum L., is a native, cross-pollinated, morphologically diverse species with an array of ploidy levels and ecotypes. Switchgrass is found throughout most of the USA and Canada, primarily east of the Rocky Mountains and south of Hudson Bay. The objective of this research was to determine if chloroplast DNA (cpDNA) restriction fragment length polymorphisms (RFLPs) occur among switchgrass cultivars and experimental strains that differ in ploidy level or ecotype classification. Eighteen switchgrass cultivars or experimental strains representative of reported ecotypes, ploidy levels, and the geographical range of switchgrass were surveyed for cpDNA polymorphisms by means of four restriction endonucleases and 20 sorghum cpDNA probes. One polymorphism was detected which was associated with the lowland-upland ecotype classification. The lowland cultivars contained a restriction site change that was not present in the upland cultivars. The two cytotypes discovered have been designated as the U (upland) or L (lowland) cytotype. The lowland cultivars had 3 pg DNA/nuclei as measured by flow cytometry while the upland types had either 3 or 6 pg DNA/nuclei. There were no cpDNA polymorphisms among the upland cultivars regardless of ploidy level as measured by DNA content. These results demonstrate that cpDNA differs among switchgrasses and that this variation is associated with ecotype variation but not with nuclear DNA content
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