Saccharification of Starchy Grain Mashes for Ethonal Fermentation Use of Mold-Amylase Preparations

Ethyl alcohol has been listed by scientists as one of the six most useful substances; in fact it has been said that, next to water, ethanol is the most useful chemical compound known to mankind. At the present time approximately 85% of all industrial alcohol is made by fermentation, the balance by synthesis from ethylene derived from the cracking of petroleum. Of the fermentation alcohol about nine-tenths is produced from blackstrap molasses, one-tenth from grains. However, by-product molasses is limited in amount and there is at the present time virtually no surplus. This is shown by the statistics of molasses production (4) and by the fact that the price of molasses has recently risen from 5¢ to 7¢ per gallon. It is likely to rise still higher as alcohol production expands to meet the needs of defense industries. Hence, other raw materials will become increasingly important. Of these, corn is the only one now available in adequate quantities in the United States. The present price of molasses at 7¢ per gallon is equivalent to about 60¢ per bushel for corn as an alcohol source

The burden of multiple sclerosis: A community health survey

© 2008 Jones et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

2-D Radiative Transfer in Protostellar Envelopes: I. Effects of Geometry on Class I Sources

We present 2-D radiation transfer models of Class I Protostars and show the effect of including more realistic geometries on the resulting spectral energy distributions and images. We begin with a rotationally flattened infalling envelope as our comparison model, and add a flared disk and bipolar cavity. The disk affects the spectral energy distribution most strongly at edge-on inclinations, causing a broad dip at about 10 um (independent of the silicate feature) due to high extinction and low scattering albedo in this wavelength region. The bipolar cavities allow more direct stellar+disk radiation to emerge into polar directions, and more scattering radiation to emerge into all directions. The wavelength-integrated flux, often interpreted as luminosity, varies with viewing angle, with pole-on viewing angles seeing 2-4 times as much flux as edge-on, depending on geometry. Thus, observational estimates of luminosity should take into account the inclination of a source. The envelopes with cavities are significantly bluer in near-IR and mid-IR color-color plots than those without cavities. Using 1-D models to interpret Class I sources with bipolar cavities would lead to an underestimate of envelope mass and an overestimate of the implied evolutionary state. We compute images at near-, mid-, and far-IR wavelengths. We find that the mid-IR colors and images are sensitive to scattering albedo, and that the flared disk shadows the midplane on large size scales at all wavelengths plotted. Finally, our models produce polarization spectra which can be used to diagnose dust properties, such as albedo variations due to grain growth. Our results of polarization across the 3.1 um ice feature agree well with observations for ice mantles covering 5% of the radius of the grains.Comment: Accepted for publication in ApJ, 37 pages, 13 figures (several figures reduced in quality; find original version at http://gemelli.colorado.edu/~bwhitney/preprints.html

Deuterium Toward Two Milky Way Disk Stars: Probing Extended Sight Lines with the Far Ultraviolet Spectroscopic Explorer

We have carried out an investigation of the abundance of deuterium along two extended sight lines through the interstellar medium (ISM) of the Galactic disk. The data include Far Ultraviolet Spectroscopic Explorer (FUSE) observations of HD 195965 (B1Ib) and HD 191877 (B0V), as well as Space Telescope Imaging Spectrograph (STIS) observations of HD 195965. The distances to HD 195965 and HD 191877, derived from spectroscopic parallax, are 794+/-200 pc and 2200+/-550 pc, respectively, making these the longest Galactic disk sight lines in which deuterium has been investigated with FUSE. The higher Lyman lines clearly show the presence of deuterium. We use a combination of curve of growth analyses and line profile fitting to determine the DI abundance toward each object. We also present column densities for OI and NI toward both stars, and HI measured from Ly-alpha absorption in the STIS spectrum of HD 195965. The D/H ratios along these sight lines are lower than the average value found with FUSE for the local interstellar medium (37 to 179 pc from the Sun). These observations lend support to earlier detections of variation in D/H over distances greater than a few hundred pc. The D/H and O/H values measured along these sight lines support the expectation that the ISM is not well mixed on distances of ~1000 pc.Comment: 32 pages, 18 figures. Abridged abstract. Accepted for publication in ApJ. Uses emulateapj5.st

Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis

The proteinase-activated receptors (PARs) are widely recognized for their modulatory properties of inflammation and neurodegeneration. We investigated the role of PAR2 in the pathogenesis of multiple sclerosis (MS) in humans and experimental autoimmune encephalomyelitis (EAE) in mice. PAR2 expression was increased on astrocytes and infiltrating macrophages in human MS and murine EAE central nervous system (CNS) white matter (P < 0.05). Macrophages and astrocytes from PAR2 wild-type (WT) and knockout (KO) mice exhibited differential immune gene expression with PAR2 KO macrophages showing significantly higher interleukin 10 production after lipopolysaccharide stimulation (P < 0.001). PAR2 activation in macrophages resulted in the release of soluble oligodendrocyte cytotoxins (P < 0.01). Myelin oligodendrocyte glycoprotein–induced EAE caused more severe inflammatory gene expression in the CNS of PAR2 WT animals (P < 0.05), together with enhanced T cell proliferation and interferon γ production (P < 0.05), compared with KO littermates. Indeed, PAR2 WT animals showed markedly greater microglial activation and T lymphocyte infiltration accompanied by worsened demyelination and axonal injury in the CNS compared with their PAR2 KO littermates. Enhanced neuropathological changes were associated with a more severe progressive relapsing disease phenotype (P < 0.001) in WT animals. These findings reveal previously unreported pathogenic interactions between CNS PAR2 expression and neuroinflammation with ensuing demyelination and axonal injury

The equation of state of solid nickel aluminide

The pressure-volume-temperature equation of state of the intermetallic compound NiAl was calculated theoretically, and compared with experimental measurements. Electron ground states were calculated for NiAl in the CsCl structure, using density functional theory, and were used to predict the cold compression curve and the density of phonon states. The Rose form of compression curve was found to reproduce the ab initio calculations well in compression but exhibited significant deviations in expansion. A thermodynamically-complete equation of state was constructed for NiAl. Shock waves were induced in crystals of NiAl by the impact of laser-launched Cu flyers and by launching NiAl flyers into transparent windows of known properties. The TRIDENT laser was used to accelerate the flyers to speeds between 100 and 600m/s. Point and line-imaging laser Doppler velocimetry was used to measure the acceleration of the flyer and the surface velocity history of the target. The velocity histories were used to deduce the stress state, and hence states on the principal Hugoniot and the flow stress. Flyers and targets were recovered from most experiments. The effect of elasticity and plastic flow in the sample and window was assessed. The ambient isotherm reproduced static compression data very well, and the predicted Hugoniot was consistent with shock compression data

Publishing and sharing multi-dimensional image data with OMERO

Imaging data are used in the life and biomedical sciences to measure the molecular and structural composition and dynamics of cells, tissues, and organisms. Datasets range in size from megabytes to terabytes and usually contain a combination of binary pixel data and metadata that describe the acquisition process and any derived results. The OMERO image data management platform allows users to securely share image datasets according to specific permissions levels: data can be held privately, shared with a set of colleagues, or made available via a public URL. Users control access by assigning data to specific Groups with defined membership and access rights. OMERO’s Permission system supports simple data sharing in a lab, collaborative data analysis, and even teaching environments. OMERO software is open source and released by the OME Consortium at www.openmicroscopy.org

Red-Cockaded Woodpecker Status and Management: West Gulf Coastal Plain and Interior Highlands

Red-cockaded woodpecker populations declined precipitously following European settlement and expansion and cutting of the original pine forests across the southeastern United States. By 1990 most residual populations lacked demographic viability, existed in degraded habitat, and were isolated from other populations. The primary causes of this situation were harvest of the original pine forests of the southeastern United States, conversion of forested lands to other uses, short-rotation silvicultural practices, and alteration of the fire regime in the regenerated forests. As social and legal mandates changed, management of red-cockaded woodpeckers became a higher priority. Intensive management for red-cockaded woodpeckers is currently practiced on most public and a few private lands that still support populations. Recent population trends and the current status of red-cockaded woodpeckers in Oklahoma, Arkansas, Texas, and Louisiana reflect historical factors and the efficacy of recent management