40 research outputs found

    Assessment of International Tourists\u27 Perception on Local Foods in Tanzania

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    Consumption of local food is broadly recognized as an essential part of tourists’ experience. Locally distinctive food can be important both as a tourism attraction in itself and in helping to shape the image of a destination. Local food experiences have the potential to contribute considerably to sustainable development, help maintain regional identities and support agricultural diversification. While local foods have the potential to reduce poverty in rural communities, their image and perception to tourists remain largely unexamined. The aim of this paper is to evaluate the way international tourists perceive local food in Tanzania. Data was collected using questionnaires (N = 540) at Kilimanjaro International Airport (KIA), which serves tourists who have just completed their visits from the most popular “Northern Circuit” of Tanzania National Parks. The findings show that (74.5%) of the respondents agreed that overall local food was of good quality and (58.5%) agreed that local food was safe to eat. However, respondents felt strongly that the hotels they stayed in did not provide many varieties of local foods (42.3%) or sufficient information about local foods (36.5%)

    International Tourism: An Unrecognized Potential in Rural Tourism Development

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    This paper presents an overview of international tourism and its role in rural economic development. It briefly describes the current approaches to rural economic development followed by a brief look at international tourism 1n the United States, and the potential for tourism in rural areas is examined. An initial step in assessing the extent to which international tourists visit rural America is determining the factors which currently attract those visitors to rural areas. The purpose of this paper is to profile potential international travelers to rural areas

    Issues in Rural Community Tourism Development

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    Policy makers are turning to tourism as a potential industry force that may bring both economic and demographic stability to American rural communities. The systematic planning and appropriate utilization of community related physical, economic, and socio-cultural attributes is the key to the establishment of sustainable tourism. This paper focuses on several issues that are increasingly recognized as critical factors in the community system. Both quality of life and sense of place are emphasized. The paper concludes with broadly defined guidelines for future planning toward sustainable development

    Pompe disease diagnosis and management guideline

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    ACMG standards and guidelines are designed primarily as an educational resource for physicians and other health care providers to help them provide quality medical genetic services. Adherence to these standards and guidelines does not necessarily ensure a successful medical outcome. These standards and guidelines should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results. in determining the propriety of any specific procedure or test, the geneticist should apply his or her own professional judgment to the specific clinical circumstances presented by the individual patient or specimen. It may be prudent, however, to document in the patient's record the rationale for any significant deviation from these standards and guidelines.Duke Univ, Med Ctr, Durham, NC 27706 USAOregon Hlth Sci Univ, Portland, OR 97201 USANYU, Sch Med, New York, NY USAUniv Florida, Coll Med, Powell Gene Therapy Ctr, Gainesville, FL 32611 USAIndiana Univ, Bloomington, in 47405 USAUniv Miami, Miller Sch Med, Coral Gables, FL 33124 USAHarvard Univ, Childrens Hosp, Sch Med, Cambridge, MA 02138 USAUniversidade Federal de SĂŁo Paulo, SĂŁo Paulo, BrazilColumbia Univ, New York, NY 10027 USANYU, Bellevue Hosp, Sch Med, New York, NY USAColumbia Univ, Med Ctr, New York, NY 10027 USAUniversidade Federal de SĂŁo Paulo, SĂŁo Paulo, BrazilWeb of Scienc

    Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

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    Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained. We report results from a GWAS meta-analysis of HF comprising 47,309 cases and 930,014 controls. Twelve independent variants at 11 genomic loci are associated with HF, all of which demonstrate one or more associations with coronary artery disease (CAD), atrial fibrillation, or reduced left ventricular function, suggesting shared genetic aetiology. Functional analysis of non-CAD-associated loci implicate genes involved in cardiac development (MYOZ1, SYNPO2L), protein homoeostasis (BAG3), and cellular senescence (CDKN1A). Mendelian randomisation analysis supports causal roles for several HF risk factors, and demonstrates CAD-independent effects for atrial fibrillation, body mass index, and hypertension. These findings extend our knowledge of the pathways underlying HF and may inform new therapeutic strategies
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