92 research outputs found
Notes on the Hamiltonian formulation of 3D Yang-Mills theory
Three-dimensional Yang-Mills theory is investigated in the Hamiltonian
formalism based on the Karabali-Nair variable. A new algorithm is developed to
obtain the renormalized Hamiltonian by identifying local counterterms in
Lagrangian with the use of fictitious holomorphic symmetry existing in the
framework with the KN variable. Our algorithm is totally algebraic and enables
one to calculate the ground state wave functional recursively in gauge
potentials. In particular, the Gaussian part thus calculated is shown to
coincide with that obtained by Leigh et al. Higher-order corrections to the
Gaussian part are also discussed.Comment: 26 pages, LaTeX; discussions on IR regulators and local counterterms
improved, references adde
TEM Measurement of Lamellar Thickness in Polyethylene and Cycloparaffins by Staining with RuO₄
Ultrastructural alteration of the cell surface of Staphylococcus aureus cultured in a different salt condition
Staphylococcus aureus growing in a normal NaGI medium
has a specific NaGI tolerance property to grow in the medium contain. ing NaGl in as high a concentration as over 10%. In our comparative study of the cells proliferating in the normal NaGI medium and 10% NaGl medium, we have observed the following differences aside from the changes of lipid composition in the cytoplasmic membrane previously reported. 1. S. aureus grown in high NaGl medium undergoes changes as to increase its size and reduce its surface area. 2. The thickness and weight of cell wall are increased to about 1. 7 times and 1. 32 times, respectively. 3. The protoplast prepared from S. aureus growing in the high NaGI medium shows a weaker resistance to hypotonic condition than that from normal cell.</p
Structural Changes of Poly(p-phenylene sulphide) on Doping (Commemoration Issue Dedicated to Professor Hiroshi Ibagaki, Professor Michio Kurata, Professor Ryozo Kitamura, On the Occasion of Their Retirments)
Construction of Image Processing Systems and Application to the Random Noise Removal in Electron Micrographs (Commemoration Issue Dedicated to Professor Keinosuke Kobayashi on the Occasion of His Retirement)
Lattice Disorders in the Stereocomplex of Poly(L-lactide) and Poly(D-lactide) (Commemoration Issue Dedicated to Professor Hiroshi Ibagaki, Professor Michio Kurata, Professor Ryozo Kitamura, On the Occasion of Their Retirments)
Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats
To evaluate the effect of coupling of recombinant human serum albumin (rHSA) onto the surface of poly(ethylene glycol)-modified liposorne (PEG liposome) on the in vivo disposition characteristics of liposomal doxorubicin (DXR), the pharmacokinetics and tissue distribution of DXR were evaluated after intravenous administration of rHSA-modified PEG (rHSA/PEG) liposomal DXR into tumor-bearing rats. rHSA/PEG liposome prepared using a hetero-bifunctional cross-linker, N- succinimidyl 3-(2-pyridyldithio) propionate (SPDP), efficiently encapsulated DXR (over 95%). rHSA/PEG liposomal DXR showed longer blood-circulating property than PEG liposornal DXR and the hepatic and splenic clearances of rHSA/PEG liposornal DXR were significantly smaller than those of PEG liposomal DXR. It was also demonstrated that the disposition of DXR to the heart, one of the organs for DXR-related side-effects, was significantly smaller than free DXR. Furthermore, the tumor accumulation of rHSA/PEG liposomal DXR was significantly larger than that of PEG liposomal DXR. The "therapeutic index", a criterion for therapeutic outcome, for rHSA/PEG fiposornal DXR was significantly higher than PEG liposomal DXR. These results clearly indicate that rHSA-conjugation onto the surface of PEG liposome would be a useful approach to increase the effectiveness and safety of PEG liposomal DXR.</p
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