Autoregressive Models

Consider a sequence of random variables which obeys a first order autoregressive model with unknown parameter alpha. Under suitable assumptions on the error structure of the model, the limiting distribution of the normalized least squares estimator of alpha is discussed. The choice of the normalizing constant depends on whether alpha is less than one, equals one, or is greater than one in absolute value. In particular, the limiting distribution is normal provided that the absolute value of alpha is less than one, but is a function of Brownian motion whenever the absolute value of alpha equals one. Some general remarks are made whenever the sequence of random variables is a first order moving average process

Trends in Undergraduate General Education in the U.S., the Texas Core Curriculum, and Communication Course Requirements

In October 2011, the Texas Higher Education Coordinating Board revised Texas Core Curriculum (TCC) rules impacting all public higher education institutions in Texas. The new rules were implemented in the fall semester of 2014. In this study, we review the history of undergraduate general education requirements in the United States and recent changes to the TCC. Then to determine how recent changes reflect historical trends in general education and affect the course offerings of departments of English and communication, we use descriptive statistics to examine courses included under the TCC Communication Foundational Component Area of 37 state universities and 53 community colleges. Findings indicate the number of re-quired English and speech communication courses decreased both at community colleges (-11.5%) and universities (-15.9%), signaling a shift toward providing students greater choice in course selection which could impact academic programs in the years to come.Educatio

National evaluation of Diplomas: cohort 1 - the second year

The introduction of Diplomas for 14-19 year olds represented a major innovation in educational opportunity for young people in England. The Diplomas are being offered at three levels and across 14 subjects and have been implemented in three phases (from September 2008, 2009 and 2010). Following the establishment of the Coalition government in May 2010, a number of changes to the implementation and delivery of the Diploma qualification were introduced. The Minister of State for Schools announced that development of new Diplomas in science, humanities and languages, which were due to be introduced from September 2011, would be discontinued. Additionally the Diploma entitlement, whereby all young people within an area would be able to access any of the Diploma subjects, would be removed and that the decision about which Diploma subjects would be available to students would in future be made by schools and colleges. Moreover, it was decided that the Gateway application process whereby consortia (of schools, colleges, training providers, employers and Higher Education Institutes (HEIs)) had previously submitted an application to the Department for Education (DfE) for each Diploma subject they wanted to offer would no longer be required for provision commencing from 2012. Other changes included the freedom for institutions to decide whether or not they wanted to work collaboratively to provide Diploma provision

Factors relating to home telehealth acceptance and usage compliance

Aim: This paper investigates the acceptance of in-home telehealth by frail older adults and carers of the Transition Care Program (TCP), and evaluates telehealth acceptance as a predictor for usage compliance. Method: A stratified random sample of participants was allocated to one of five groups: either a control group or to receive telehealth monitoring of their vital signs for a period of 12 or 24 weeks; with or without a medical alarm pendant. Results: Before being trained in and using telehealth, the majority of participants and carers demonstrated acceptance of the technology by reporting that they perceived it would be “useful” and “easy to use.” This acceptance was also reported post-TCP (up to 12 weeks of usage). The “perceived ease of use” of the telehealth equipment increased significantly from pre-telehealth training and usage to post-TCP (up to 12 weeks of usage) (P = 0.001). There was no change, (pre-training and usage to post-TCP) in the “perceived usefulness” of the telehealth equipment. The telehealth acceptance constructs of “ease of use” and “usefulness,” at pre-telehealth training and usage, approached statistical significance as a predictor of future compliance (P = 0.06). “Perceived ease of use,” at pre-training and usage, had a positive relationship with future compliance (P = 0.02). Conclusion: There is currently limited knowledge about the influences and determinants of home telehealth compliance in frail older people and their carers, potentially a significant user group for the technology into the future. This study’s finding that frail older people and their carers perceive that home telehealth is useful and easy to use demonstrates their acceptance of home telehealth as a therapeutic tool. Further, perceived ease of use of home telehealth is a significant predictor of compliance with frail older people and their carers’ use of home telehealth. Additional research is required in order to identify other influences and determinants of home telehealth compliance with this group. Knowledge about the influences and determinants of home telehealth compliance may assist the development of targeted interventions aimed at encouraging high compliance with users who are recording lower reading rates

Comparative Study of Terrestrial Arthropod Diversity in Primary and Re-planted Pine Forest in a Community Forest at Andasibe, Madagascar

This study is a comparison of tree and terrestrial arthropod diversity along native andre-planted pine transects.Transects were laid in a primary and re-planted pine forest in Andasibe Community Forest Park. Data was collected over six days, taking measurements of trees, inspecting and collecting specimens from pitfall traps once a day. Terrestrial arthropods were identified to morphospecies and measures of diversity were calculated. To understand the health of the trees, information was collected that included trees diameter at breast height, canopy cover and soil cover. Terrestrial arthropod communities and diversity were found to be significantly different in the native and replanted pine transects, likely due to the difference in non-native trees

Assessing pain through behavioural observation

Background: The health inequalities faced by people with intellectual disabilities (ID) are well documented, affecting both duration and quality of life. Painful health conditions can be difficult to recognise as many people with ID struggle to self-report their pain. Therefore it is important that accurate observational tools are available to support recognition and assessment of pain in people with ID. Aim: This thesis seeks to assess the use of currently available observational assessments of pain through meta-analytic methods, and then evaluates a more specialist observational tool designed to detect gastric pain. Meta-analysis: A comprehensive review of the literature found 62 distinct observational measures used in published research. The five most commonly used measures were assessed through a series of meta-analyses, synthesising correlations between observational and self-report measures of pain. Moderate correlations were found for all observational measures compared to self-report, though unacceptable levels of heterogeneity were also identified. Recommendations are made for use of the Face, Legs, Activity, Crying, Consolability scale. Empirical paper: The Gastric Distress Questionnaire (GDQ) is a parent report measure designed to screen for Gastro-oesophageal Reflux Disease (GORD), a painful health condition which is common in people with ID. Significant differences in GDQ scores were found between children with and without recent GORD. A clinical cut off is recommended for the use of the GDQ to screen for reflux. Behavioural observation by a naïve observer was not found to associate to GDQ scores provided by a parent, emphasising the importance of caregiver report in identifying GORD

Interactive programme to enhance protective factors for eating disorders in girls with type 1 diabetes

"This is the peer reviewed version of the following article: [Wilksch, S. M., Starkey, K., Gannoni, A., Kelly, T. and Wade, T. D. (2013), Interactive programme to enhance protective factors for eating disorders in girls with type 1 diabetes. Early Intervention in Psychiatry, 7: 315–321], which has been published in final form at [http://dx.doi.org/10.1111/eip.12012]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms"AIMS: This study evaluated the effectiveness of a pilot programme in enhancing protective factors for eating disorders in young girls with type 1 diabetes (T1D). METHODS: Twenty girls with T1D (M age = 11.06 years) attended two 4-h group sessions. A 4-week baseline control period was compared against changes at post-programme and at 1-month follow-up on measures of eating disorder risk factors and indicators of glycaemic control. RESULTS: At post-intervention, significant improvements were found for self-efficacy related to diabetes management, self-esteem, body-esteem,thin-ideal internalization and perfectionism. These gains were maintained at 1-month follow-up. Participants were also rated by their parents as assuming more responsibility for specific diabetes-related tasks at follow-up. CONCLUSIONS: A brief interactive programme can favourably impact protective factors for disordered eating. The development of effective disordered eating prevention strategies for girls with T1D is an urgent priority and the current study is a first step in this direction

Wind climate trends in the Pacific Northwest and the implications to renewable energy supply

EXTRACT (SEE PDF FOR FULL ABSTRACT): This paper examines the influence of wind climate variations on new Pacific Northwest renewable energy sources. Wind represents a potentially valuable supplemental source of energy in the region. ... The recent period of weaker winds may be associated with a stronger North Pacific Low in the last decade. This would result in winter storms more often being deflected farther north, to Canada. Also, in the last dozen years, lower SOI values were common. Other investigators have found low SOI to be associated with drier conditions in the Pacific Northwest

Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release

S.B. was supported by a Motor Neuron Disease Association studentship (WadeMartins/Oct13/867-792) and D.A.B was supported by the Monument Trust Discovery Award (J-1403) from Parkinson’s UK. The work was supported by the Medical Research Council Dementias Platform UK Stem Cell Network (Grant MR/M024962/1 to RW-M).A large hexanucleotide repeat expansion in the C9ORF72 gene is the most prevalent cause of amyotrophic lateral sclerosis (ALS). To better understand neuronal dysfunction during ALS progression, we studied motor neuron (MN) cultures derived from iPSC lines generated from C9ORF72 (C9) expansion carriers and unaffected controls. C9 and control MN cultures showed comparable mRNA levels for MN markers SMI-32, HB9 and ISL1 and similar MN yields (> 50% TUJ1/SMI-32 double-positive MNs). Using whole-cell patch clamp we showed that C9-MNs have normal membrane capacitance, resistance and resting potential. However, immature (day 40) C9-MNs exhibited a hyperexcitable phenotype concurrent with increased release of calcium (Ca2+) from internal stores, but with no changes to NaV and KV currents. Interestingly, this was a transient phenotype. By day 47, maturing C9-MNs demonstrated normal electrophysiological activity, displaying only subtle alterations on mitochondrial Ca2+ release. Together, these findings suggest the potential importance of a developmental component to C9ORF72-related ALS.Publisher PDFPeer reviewe