607 research outputs found

    Feature Repurposing and Cognitive Efficiency in Financial Trading Systems

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    Many IS research domains such as cognitive fit and information overload assume that the user selects from a fixed menu of IS features to accomplish goals. IS pliability researchers offer a new perspective by recognizing the users’ discretion in altering or creating new features. While this IS pliability research has important implications, it is currently descriptive rather than explanatory. To explore IS pliability in the form of causal propositions, we examine data from a Fortune 1000 brokerage firm where some traders created what the IS developers considered superfluous “extra” accounts. Levering insights from the referent theory of cognitive niche construction, we propose that these multiple accounts align the representation of information presented with the users’ conceptual trading strategies. This alignment in turn facilitates trading research through the reduction of task switching and the learning benefits supported by category labels. The empirical analysis is consistent with these propositions

    Going IT Alone: The Experienced IT Worker as Integrator of Business and IT Domains of Knowledge

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    Though the need for user participation to successfully develop information systems is a commonly accepted MIS axiom, empirical studies have failed to consistently establish the benefits of user participation. To resolve this paradox, we reconsider the underlying premise that business knowledge must be provided by business workers. Instead, as IT is embedded in the business, IT workers necessarily learn both domains in the act of work, and the integration of the two can be achieved through experienced IT workers. To examine this proposition, we studied a group of IT workers who implemented an IS in forty-seven sites over a two year period. Through learning curve methods and change-point analysis, we find that the IT workers achieved greater success as their experience increased while concurrently user participation activities decreased. These findings, consistent with the main proposition, suggest a new approach to valuing the IT workers’ contributions

    Social cognition, impulsivity, and emotion regulation factors in aggressive behavior among children with attention-deficit/hyperactivity disorder.

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    Children with Attention-Deficit/Hyperactivity Disorder (ADHD) exhibit greater levels of aggressive behavior than their typically developing peers, often resulting in impairment in social and family functioning. Aggressive behavior is often differentiated into two functions: reactive, or “hot-blooded” and proactive, or “cold-blooded” aggression. Prior research has identified several factors contributing to aggressive behavior within a general population, including emotion dysregulation, negative urgency, social information processing (SIP), and parenting behaviors. A paucity of research has examined these factors within an ADHD population. Thus, the present study aimed to examine social, emotional, behavioral, and cognitive factors associated with aggression among children with ADHD. Specifically, the present study investigated the independent and combined roles of emotion dysregulation and negative urgency in reactive aggression as well as the independent and interactive roles of SIP and parenting behaviors in proactive aggression. Participants included 28 children with ADHD and their parents. Participants, their parents, and their teachers completed questionnaires to assess emotion dysregulation, negative urgency, aggressive behavior, and parenting behaviors. Parents completed a diagnostic interview to confirm ADHD diagnostic status. Children completed one task to assess aggression and responded to social vignettes to assess social information processing. Of note, the data collection was prematurely discontinued due to the emergence of the COVID-19 pandemic; therefore, results of the present study should be interpreted with caution due to low power. Hypothesis 1 was partially supported, such that emotion dysregulation significantly estimated reactive aggression regardless of reporter. Further, negative urgency significantly estimated reactive aggression when reported by parents, but not by teachers. Contrary to hypothesis 2, SIP did not significantly estimate proactive aggression, and no interaction between SIP and parenting behaviors was observed. However, inconsistent discipline did significantly estimate proactive aggression suggesting learning history and environment play an important role in proactive aggression. Finally, contrary to hypothesis 3, no indirect effect of emotion dysregulation on reactive aggression through negative urgency were observed; however, these results are inconclusive due to low power. Findings of the present results have significant implications for the way in which aggression is conceptualized, as well as clinical implications for the treatment of aggressive behavior among children with ADHD

    Graduate Brass Quintet Recital

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    Kemp Recital Hall Thursday April 12, 2001 6:30p.m

    The economic and innovation contribution of universities: a regional perspective

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    Universities and other higher education institutions (HEIs) have come to be regarded as key sources of knowledge utilisable in the pursuit of economic growth. Although there have been numerous studies assessing the economic and innovation impact of HEIs, there has been little systematic analysis of differences in the relative contribution of HEIs across regions. This paper provides an exploration of some of these differences in the context of the UK’s regions. Significant differences are found in the wealth generated by universities according to regional location and type of institution. Universities in more competitive regions are generally more productive than those located in less competitive regions. Also, traditional universities are generally more productive than their newer counterparts, with university productivity positively related to knowledge commercialisation capabilities. Weaker regions tend to be more dependent on their universities for income and innovation, but often these universities under-perform in comparison to counterpart institutions in more competitive regions. It is argued that uncompetitive regions lack the additional knowledge infrastructure, besides universities, that are more commonly a feature of more competitive regions

    "Women's rights, the European Court and Supranational Constitutionalism"

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    This analysis examines supranational constitutionalism in the European Union. In particular, the study focuses on the role of the European Court of Justice in the creation of women’s rights. I examine the interaction between the Court and member state governments in legal integration, and also the integral role that women’s advocates – both individual activists and groups – have played in the development of EU social provisions. The findings suggest that this litigation dynamic can have the effect of fueling the integration process by creating new rights that may empower social actors and EU organizations, with the ultimate effect of diminishing member state government control over the scope and direction of EU law. This study focuses specifically on gender equality law, yet provides a general framework for examining the case law in subsequent legal domains, with the purpose of providing a more nuanced understanding of supranational governance and constitutionalism

    Concert recording 2016-04-19a

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    [Track 01]. Canzon duodecimi toni / Giovanni Gabrieli -- [Track 02]. Divertissement. Andante - allegro ; [Track 03]. Allegro vivace ; [Track 04]. Andante / Emile Bernard -- [Track 05]. March for military music in F major, Yorck march WoO 18 / Ludwig van Beethoven -- [Track 06]. Sept danses. Le jeu de la poupée ; [Track 07]. Funérailles de la poupée ; [Track 08]. La présentation des petits amis ; [Track 09]. Variation de Paul ; [Track 10]. Pas de deux entre Sophie et Paul ; [Track 11]. La goûter ; [Track 12]. Danse des filets à papillons / Jean Françaix

    De Novo Growth Zone Formation from Fission Yeast Spheroplasts

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    Eukaryotic cells often form polarized growth zones in response to internal or external cues. To understand the establishment of growth zones with specific dimensions we used fission yeast, which grows as a rod-shaped cell of near-constant width from growth zones located at the cell tips. Removing the cell wall creates a round spheroplast with a disorganized cytoskeleton and depolarized growth proteins. As spheroplasts recover, new growth zones form that resemble normal growing cell tips in shape and width, and polarized growth resumes. Regulators of the GTPase Cdc42, which control width in exponentially growing cells, also control spheroplast growth zone width. During recovery the Cdc42 scaffold Scd2 forms a polarized patch in the rounded spheroplast, demonstrating that a growth zone protein can organize independent of cell shape. Rga4, a Cdc42 GTPase activating protein (GAP) that is excluded from cell tips, is initially distributed throughout the spheroplast membrane, but is excluded from the growth zone after a stable patch of Scd2 forms. These results provide evidence that growth zones with normal width and protein localization can form de novo through sequential organization of cellular domains, and that the size of these growth zones is genetically controlled, independent of preexisting cell shape

    In Vivo Raman Spectroscopy for Biochemical Monitoring of the Human Cervix Throughout Pregnancy

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    Background The cervix must undergo significant biochemical remodeling to allow for successful parturition. This process is not fully understood, especially in instances of spontaneous preterm birth. In vivo Raman spectroscopy is an optical technique that can be used to investigate the biochemical composition of tissue longitudinally and noninvasively in human beings, and has been utilized to measure physiology and disease states in a variety of medical applications. Objective The purpose of this study is to measure in vivo Raman spectra of the cervix throughout pregnancy in women, and to identify biochemical markers that change with the preparation for delivery and postpartum repair. Study Design In all, 68 healthy pregnant women were recruited. Raman spectra were measured from the cervix of each patient monthly in the first and second trimesters, weekly in the third trimester, and at the 6-week postpartum visit. Raman spectra were measured using an in vivo Raman system with an optical fiber probe to excite the tissue with 785 nm light. A spectral model was developed to highlight spectral regions that undergo the most changes throughout pregnancy, which were subsequently used for identifying Raman peaks for further analysis. These peaks were analyzed longitudinally to determine if they underwent significant changes over the course of pregnancy (P \u3c .05). Finally, 6 individual components that comprise key biochemical constituents of the human cervix were measured to extract their contributions in spectral changes throughout pregnancy using a linear combination method. Patient factors including body mass index and parity were included as variables in these analyses. Results Raman peaks indicative of extracellular matrix proteins (1248 and 1254 cm−1) significantly decreased (P \u3c .05), while peaks corresponding to blood (1233 and 1563 cm–1) significantly increased (P \u3c .0005) in a linear manner throughout pregnancy. In the postpartum cervix, significant increases in peaks corresponding to actin (1003, 1339, and 1657 cm–1) and cholesterol (1447 cm–1) were observed when compared to late gestation, while signatures from blood significantly decreased. Postpartum actin signals were significantly higher than early pregnancy, whereas extracellular matrix proteins and water signals were significantly lower than early weeks of gestation. Parity had a significant effect on blood and extracellular matrix protein signals, with nulliparous patients having significant increases in blood signals throughout pregnancy, and higher extracellular matrix protein signals in early pregnancy compared to patients with prior pregnancies. Body mass index significantly affected actin signal contribution, with low body mass index patients showing decreasing actin contribution throughout pregnancy and high body mass index patients demonstrating increasing actin signals. Conclusion Raman spectroscopy was successfully used to biochemically monitor cervical remodeling in pregnant women during prenatal visits. This foundational study has demonstrated sensitivity to known biochemical dynamics that occur during cervical remodeling, and identified patient variables that have significant effects on Raman spectra throughout pregnancy. Raman spectroscopy has the potential to improve our understanding of cervical maturation, and be used as a noninvasive preterm birth risk assessment tool to reduce the incidence, morbidity, and mortality caused by preterm birth
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