3,141 research outputs found
Driving a Wedge Between Evidence and Beliefs: How Online Ideological News Exposure Promotes Political Misperceptions
This article has 2 goals: to provide additional evidence that exposure to ideological online news media contributes to political misperceptions, and to test 3 forms this media‐effect might take. Analyses are based on representative survey data collected during the 2012 U.S. presidential election (N = 1,004). Panel data offer persuasive evidence that biased news site use promotes inaccurate beliefs, while cross‐sectional data provide insight into the nature of these effects. There is no evidence that exposure to ideological media reduces awareness of politically unfavorable evidence, though in some circumstances biased media do promote misunderstandings of it. The strongest and most consistent influence of ideological media exposure is to encourage inaccurate beliefs regardless of what consumers know of the evidence.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134259/1/jcc412164_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134259/2/jcc412164.pd
Using Aerial Hyperspectral Remote Sensing Imagery to Estimate Corn Plant Stand Density
Since corn plant stand density is important for optimizing crop yield, several researchers have recently developed ground-based systems for automatic measurement of this crop growth parameter. Our objective was to use data from such a system to assess the potential for estimation of corn plant stand density using remote sensing images. Aerial hyperspectral remote sensing imagery was collected on three dates over three plots of corn in central Iowa during the 2004 growing season. The imagery had a spatial resolution of 1 m and a spectral resolution of 3 nm between 498 nm and 855 nm. A machine vision system for early-season measurement of corn plant stand density was also used to map every row of corn within the three plots, and a complete inventory of corn plants was generated as a rich ground reference dataset. A principal component regression analysis was used to assess relationships between plant stand density measurements and principal components of hyperspectral reflectance for each plot, on each image collection date, and at three different spatial resolutions (2, 6, and 10 m). The maximum R2 for regressions was 0.79. Estimates of corn plant stand density were best when using imagery collected at the later vegetative and early reproductive corn growth stages. Quantization effects due to row width complicated corn plant stand density estimates at 2 m spatial resolution, and better estimations were typically seen at resolutions of 6 m and 10 m. Among the different cases of plot, image date, and spatial resolution, the principal components of reflectance most highly correlated with plant stand density were able to be classified into four distinct types, denoted as types A, B, C, and D. Type A principal components contrasted all available visible red wavelengths with all available near-infrared wavelengths. Type B principal components contrasted green wavelengths (531 to 552 nm) plus shorter wave near-infrared (759 nm) with red wavelengths (675 to 693 nm) plus longer wave near-infrared (852 nm). Type C principal components summed green wavelengths (528 to 546 nm) and near-infrared wavelengths (717 to 855 nm). Type D principal components contrasted blue/green wavelengths (498 to 507 nm) with the red edge (717 nm). Remote sensing can be best used to estimate corn plant stand density at mid-season as long as plant stand variability exists and variability due to other factors is minimal
Ecophysiology of coral reef primary producers across an upwelling gradient in the tropical central Pacific
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Johnson, M. D., Fox, M. D., Kelly, E. L. A., Zgliczynski, B. J., Sandin, S. A., & Smith, J. E. Ecophysiology of coral reef primary producers across an upwelling gradient in the tropical central Pacific. Plos One, 15(2), (2020): e0228448, doi:10.1371/journal.pone.0228448.Upwelling is an important source of inorganic nutrients in marine systems, yet little is known about how gradients in upwelling affect primary producers on coral reefs. The Southern Line Islands span a natural gradient of inorganic nutrient concentrations across the equatorial upwelling region in the central Pacific. We used this gradient to test the hypothesis that benthic autotroph ecophysiology is enhanced on nutrient-enriched reefs. We measured metabolism and photophysiology of common benthic taxa, including the algae Porolithon, Avrainvillea, and Halimeda, and the corals Pocillopora and Montipora. We found that temperature (27.2–28.7°C) was inversely related to dissolved inorganic nitrogen (0.46–4.63 μM) and surface chlorophyll a concentrations (0.108–0.147 mg m-3), which increased near the equator. Contrary to our prediction, ecophysiology did not consistently track these patterns in all taxa. Though metabolic rates were generally variable, Porolithon and Avrainvillea photosynthesis was highest at the most productive and equatorial island (northernmost). Porolithon photosynthetic rates also generally increased with proximity to the equator. Photophysiology (maximum quantum yield) increased near the equator and was highest at northern islands in all taxa. Photosynthetic pigments also were variable, but chlorophyll a and carotenoids in Avrainvillea and Montipora were highest at the northern islands. Phycobilin pigments of Porolithon responded most consistently across the upwelling gradient, with higher phycoerythrin concentrations closer to the equator. Our findings demonstrate that the effects of in situ nutrient enrichment on benthic autotrophs may be more complex than laboratory experiments indicate. While upwelling is an important feature in some reef ecosystems, ancillary factors may regulate the associated consequences of nutrient enrichment on benthic reef organisms.This work was supported by funding from the Moore Family Foundation, the Gordon and Betty Moore Foundation, the Scripps family, and anonymous donors. The funders had no role in study design, data collection and analysis, or preparation of the manuscript
Formulation preference, tolerability and quality of life assessment following a switch from lopinavir/ritonavir soft gel capsule to tablet in human immunodeficiency virus-infected patients
<p>Abstract</p> <p>Background</p> <p>Lopinavir/ritonavir (LPV/r) tablet compared to the soft gel capsule (SGC) formulation has no oleic acid or sorbitol, has no refrigeration or food-restriction requirements, and has less pharmacokinetic variability. We compared the tolerability, quality of life (QoL), and formulation preference after switching from LPV/r SGC to the tablet formulation.</p> <p>Methods</p> <p>In a prospective, single-arm, cohort study-design, 74 human immunodeficiency virus (HIV) infected subjects stable on LPV/r-based therapy were enrolled prior to (n = 25) or 8 weeks (n = 49) after switching from SGC to tablet. Baseline data included clinical laboratory tests, bowel habit survey (BHS) and QoL questionnaire (recalled if enrolled post-switch). Global Condition Improvement (GCI)-score, BHS-score, QoL-score, and formulation preference data were captured at weeks 4 and 12.</p> <p>Results</p> <p>At week 12 post-enrollment; the tablet was preferred to the SGC (74% vs. 10%, p < 0.0001). GCI-overall-tolerability score was 2.46 ± 3.30 on a scale of -7 to +7, with 90% admitting to feeling better or about the same. Stool frequency, consistency, volume, and ± blood improved, however the improvement was significant in "consistency" only (p = 0.03). Aggregate Bowel Habit-Profile improved (BHS-score change = -0.227, p = 0.01). Inverse relationship existed between GCI and BHS (slope = -1.2, p = 0.02) at week-4, suggesting that improved overall-tolerability was related to better gastrointestinal (GI)-tolerance. QoL-scores were stable. Mean reductions in total cholesterol of 9.20 mg/dL (p = 0.02), in triglycerides of 33 mg/dL (p = 0.04), and in HDL of 4.50 mg/dL (p = 0.01) unrelated to lipid-lowering therapy, were observed at week 12.</p> <p>Conclusions</p> <p>LPV/r-tablet was well tolerated and preferred to the SGC in HIV infected subjects, with stable QoL and appreciable improvement in GI-tolerability. The unexpected changes in lipid profile deserve further evaluation.</p
What clonal hematopoiesis can teach us about MDS
Clonal hematopoiesis (CH), defined as the clonal expansion of mutated hematopoietic stem and progenitor cells (HSPCs), is a common aging process. CH is a risk factor for the development of hematologic malignancies, most commonly myeloid neoplasms (MNs) including acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and myeloproliferative neoplasm (MPN). Recent work has elucidated how the development and cellular fitness of CH is shaped by aging, environmental exposures, and the germline (inherited) genetic background of an individual. This in turn has provided valuable insights into the pathogenesis of MNs including MDS. Here, in this review, we discuss the genetic origins of CH, the environmental stressors that influence CH, and the implications of CH on health outcomes including MDS. Since MNs have shared risk factors and underlying biology, most of our discussion regarding the implications of CH surrounds MN in general rather than focusing specifically on MDS. We conclude with future directions and areas of investigation including how intervention studies of CH might inform future therapeutic approaches to MN including MDS
Sensor node localisation using a stereo camera rig
In this paper, we use stereo vision processing techniques to
detect and localise sensors used for monitoring simulated
environmental events within an experimental sensor network testbed. Our sensor nodes communicate to the camera through patterns emitted by light emitting diodes (LEDs). Ultimately, we envisage the use of very low-cost, low-power,
compact microcontroller-based sensing nodes that employ
LED communication rather than power hungry RF to transmit data that is gathered via existing CCTV infrastructure.
To facilitate our research, we have constructed a controlled
environment where nodes and cameras can be deployed and
potentially hazardous chemical or physical plumes can be
introduced to simulate environmental pollution events in a
controlled manner. In this paper we show how 3D spatial
localisation of sensors becomes a straightforward task when
a stereo camera rig is used rather than a more usual 2D
CCTV camera
Conducting Research in Non-Traditional Settings: Research Assistant Experiences in a Gay Bathhouse
Research conducted in traditional and non-traditional settings remains essential to understanding behaviors and attitudes among diverse populations. The effective preparation of research assistants is essential in order to conduct ethical research and ensure safety for the participants and those conducting the research. One such example pertains to examining the behavior of men who have sex with men (e.g., gay, bisexual, other MSM) within bathhouse settings. Semi-structured interviews were conducted among six graduate students and alumni examining their overall interest in conducting research as well as their thoughts and feelings prior to, during, and after collecting data at a gay male bathhouse, and the overall impact upon their professional growth and development. Thematic findings centered around conducting research within a bathhouse setting, navigating personal feelings and reactions, and strengthening connections between personal and professional selves, among others. Implications for effectively training and preparing student research assistants to conduct data collection with unique and non-traditional settings will be examined
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