13,027 research outputs found

    Finite element meshing of ANSYS (trademark) solid models

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    A large scale, general purpose finite element computer program, ANSYS, developed and marketed by Swanson Analysis Systems, Inc. is discussed. ANSYS was perhaps the first commercially available program to offer truly interactive finite element model generation. ANSYS's purpose is for solid modeling. This application is briefly discussed and illustrated

    Brief Report: Exercise and Anxiety in Adults with Arthritis and Other Rheumatic Diseases: Support for Evidential Value

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    Objective. Given the high prevalence of anxiety in adults with arthritis and other rheumatic diseases (AORD) and the subsequent need for interventions to reduce anxiety, this brief report sought to determine if evidential value exists to support the role of exercise for reducing anxiety in adults with AORD. Methods. Utilizing data from a prior meta-analysis, a recently developed approach, P- curve, was used to determine evidential value by assessing for publication bias and p-hacking. Binomial tests as well as the more robust Stouffer’s test were used to examine for evidential value. To examine the influence of selected studies on p-curve results, findings were also examined by dropping the highest and lowest p values from the analysis. Results. The binomial test for evidential value was not statistically significant (p = 0.11) while the more robust Stouffer’s test satisfied both conditions for evidential value (p = 0.002). Power analyses suggested a good fit for the observed p-curve. Results were generally robust when the least and most extreme values were excluded. Conclusions. The results of this study provide evidential support for the benefits of exercise on anxiety in adults with AORD

    Clinical relevance of Tai Chi on pain and physical function in adults with knee osteoarthritis: An ancillary meta-analysis of randomized controlled trials

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    The clinical relevance of Tai Chi on pain, stiffness, and physical function in adults with knee osteoarthritis (KOA) has not been established. Therefore, the purpose of the current study was to address this gap. Eight randomized controlled trials from a recent meta-analysis representing 407 participants (216 Tai Chi, 191 control) in adults ≥18 years of age with KOA and included the assessment of pain, stiffness, and physical function using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) were assessed. The inverse variance heterogeneity model (IVhet) was first used to pool standardized mean difference effect sizes (ES) for each outcome. Clinical relevance, i.e., number-needed-to treat (NNT) ≤10 and relative risk reduction (RRR) ≥25% was calculated across assumed controlled risks (ACR) ranging from 0.01 to 0.99. Statistically significant improvements were found for pain (ES, −0.75, 95% CI, −0.99, −0.51; Q = 8.9, p = 0.26; I2 = 21%), stiffness (ES, −0.70, 95% CI, −0.95, −0.46; Q = 9.6, p = 0.21; I2 = 27%), and physical function (ES, −0.91, 95% CI, −1.12, −0.70; Q = 7.2, p = 0.40; I2 = 3%). The intersection of results for a NNT ≤10 and RRR ≥25% yielded high evidence and clinically relevant improvements across a wide range of ACR for pain (0.15 to 0.88), stiffness (0.15 to 0.87), and physical function (0.13 to 0.97). These findings suggest that Tai Chi results in statistically significant as well as clinically important improvements in pain, stiffness, and physical function across a wide range of ACR in adults with KOA

    The Comparability of Men Who Have Sex With Men Recruited From Venue-Time-Space Sampling and Facebook: A Cohort Study

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    Background: Recruiting valid samples of men who have sex with men (MSM) is a key component of the US human immunodeficiency virus (HIV) surveillance and of research studies seeking to improve HIV prevention for MSM. Social media, such as Facebook, may present an opportunity to reach broad samples of MSM, but the extent to which those samples are comparable with men recruited from venue-based, time-space sampling (VBTS) is unknown. Objective: The objective of this study was to assess the comparability of MSM recruited via VBTS and Facebook. Methods: HIV-negative and HIV-positive black and white MSM were recruited from June 2010 to December 2012 using VBTS and Facebook in Atlanta, GA. We compared the self-reported venue attendance, demographic characteristics, sexual and risk behaviors, history of HIV-testing, and HIV and sexually transmitted infection (STI) prevalence between Facebook- and VTBS-recruited MSM overall and by race. Multivariate logistic and negative binomial models estimated age/race adjusted ratios. The Kaplan-Meier method was used to assess 24-month retention. Results: We recruited 803 MSM, of whom 110 (34/110, 30.9% black MSM, 76/110, 69.1% white MSM) were recruited via Facebook and 693 (420/693, 60.6% black MSM, 273/693, 39.4% white MSM) were recruited through VTBS. Facebook recruits had high rates of venue attendance in the previous month (26/34, 77% among black and 71/76, 93% among white MSM; between-race P=.01). MSM recruited on Facebook were generally older, with significant age differences among black MSM (P=.02), but not white MSM (P=.14). … See full text for complete abstract

    K-causality and degenerate spacetimes

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    The causal relation K+K^+ was introduced by Sorkin and Woolgar to extend the standard causal analysis of C2C^2 spacetimes to those that are only C0C^0. Most of their results also hold true in the case of spacetimes with degeneracies. In this paper we seek to examine K+K^+ explicitly in the case of Lorentzian topology changing Morse spacetimes containing isolated degeneracies. We first demonstrate some interesting features of this relation in globally Lorentzian spacetimes. In particular, we show that K+K^+ is robust and that it coincides with the Seifert relation when the spacetime is stably causal. Moreover, the Hawking and Sachs characterisation of causal continuity translates into a natural expression in terms of K+K^+ for general spacetimes. We then examine K+K^+ in topology changing Morse spacetimes both with and without the degeneracies and find further characterisations of causal continuity.Comment: Latex, 23 pages, 4 figure

    Measuring Population Transmission Potential for HIV: An Alternative Metric of Transmission Risk in Men who have Sex with Men (MSM) in the US

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    Background Various metrics for HIV burden and treatment success [e.g. HIV prevalence, community viral load (CVL), population viral load (PVL), percent of HIV-positive persons with undetectable viral load] have important public health limitations for understanding disparities. Methods and Findings Using data from an ongoing HIV incidence cohort of black and white men who have sex with men (MSM), we propose a new metric to measure the prevalence of those at risk of transmitting HIV and illustrate its value. …See full text for complete abstract

    Near-UV OH Prompt Emission in the Innermost Coma of 103P/Hartley 2

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    The Deep Impact spacecraft fly-by of comet 103P/Hartley 2 occurred on 2010 November 4, one week after perihelion with a closest approach (CA) distance of about 700 km. We used narrowband images obtained by the Medium Resolution Imager (MRI) onboard the spacecraft to study the gas and dust in the innermost coma. We derived an overall dust reddening of 15\%/100 nm between 345 and 749 nm and identified a blue enhancement in the dust coma in the sunward direction within 5 km from the nucleus, which we interpret as a localized enrichment in water ice. OH column density maps show an anti-sunward enhancement throughout the encounter except for the highest resolution images, acquired at CA, where a radial jet becomes visible in the innermost coma, extending up to 12 km from the nucleus. The OH distribution in the inner coma is very different from that expected for a fragment species. Instead, it correlates well with the water vapor map derived by the HRI-IR instrument onboard Deep Impact \citep{AHearn2011}. Radial profiles of the OH column density and derived water production rates show an excess of OH emission during CA that cannot be explained with pure fluorescence. We attribute this excess to a prompt emission process where photodissociation of H2_2O directly produces excited OH*(A2Σ+A^2\it{\Sigma}^+) radicals. Our observations provide the first direct imaging of Near-UV prompt emission of OH. We therefore suggest the use of a dedicated filter centered at 318.8 nm to directly trace the water in the coma of comets.Comment: 21 page

    A Distribution of Large Particles in the Coma of Comet 103P/Hartley 2

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    The coma of comet 103P/Hartley 2 has a significant population of large particles observed as point sources in images taken by the Deep Impact spacecraft. We measure their spatial and flux distributions, and attempt to constrain their composition. The flux distribution of these particles implies a very steep size distribution with power-law slopes ranging from -6.6 to -4.7. The radii of the particles extend up to 20 cm, and perhaps up to 2 m, but their exact sizes depend on their unknown light scattering properties. We consider two cases: bright icy material, and dark dusty material. The icy case better describes the particles if water sublimation from the particles causes a significant rocket force, which we propose as the best method to account for the observed spatial distribution. Solar radiation is a plausible alternative, but only if the particles are very low density aggregates. If we treat the particles as mini-nuclei, we estimate they account for <16-80% of the comet's total water production rate (within 20.6 km). Dark dusty particles, however, are not favored based on mass arguments. The water production rate from bright icy particles is constrained with an upper limit of 0.1 to 0.5% of the total water production rate of the comet. If indeed icy with a high albedo, these particles do not appear to account for the comet's large water production rate. production rate. Erratum: We have corrected the radii and masses of the large particles of comet 103P/Hartley 2 and present revised conclusions in the attached erratum.Comment: Original article: 46 pages, 17 figures, 5 tables, published in Icarus. Erratum: 5 pages, 1 table, accepted for publication in Icaru
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