Analisis Faktor-faktor yang Mempengaruhi Penerimaan Budidaya Mawar ( Studi Kasus : Desa Bangun Sari, Kecamatan Tanjung Morawa, Kabupaten Deli Serdang)

Penelitian ini bertujuan untuk mengetahui analisis faktor-faktor yang mempengaruhi penerimaan budidaya mawar di Desa Bangun Sari, Kecamatan Tanjung Morawa, Kabupaten Deli Serdang. Diantaranya dengan menganalisis pengelolaan budidaya mawar di daerah penelitian, menganalisis pendapatan budidaya, menganalisis regresi linear berganda dengan metode OLS (Ordinary Least Square), menganalisis kelayakan budidaya dengan metode R/C ratio. Penelitian ini menggunakan data primer yang diperoleh dari petani melalui wawancara langsung dengan menggunakan daftar pertanyaan yang telah dipersiapkan terlebih dahulu. Petani responden diambil dengan menggunakan metode slovin sehingga ditentukan besar sampel petani mawar sebanyak 32 orang yang mengusahakan budidaya mawar. Metode analisis data yang digunakan adalah analisis pengelolaan budidaya mawar, pendapatan OLS (Ordinary Least Square), dan R/C ratio. Hasil penelitian menunjukkan bahwa hasil pengelolaan budidaya mawar sudah terlaksana dengan baik sesuai teknik budidaya. Pendapatan bersih yang diperoleh dengan menggunakan perhitungan tenaga kerja luar keluarga sebesar Rp. 1.994.847,406 dan pendapatan bersih yang diperoleh dengan perhitungan tenaga kerja dalam keluarga dan tenaga kerja luar keluarga sebesar Rp. 1.620.003. Hasil regresi dari metode OLS (Ordinary Least Square) diperoleh persamaan Y = -531879,936 + 1458,429 X1 + 1,312 X2 – 65414,719 X3 – 20378,571 X

Reducing variation in advanced logic technology: approaches to process and design for manufacturability of nanoscale CMOS,”

Abstract This paper presents an overview of process variation effects, including examples of mitigation strategies and test methods. Experimental and theoretical comparisons are presented for both 45nm and 65nm RDF. SRAM matching and interconnect variation is discussed for both 65nm and 45nm, including examples of process and design mitigation strategies. Use of ring oscillators for detailed measurement of within-wafer and within-die variation is illustrated for 65nm and 45nm product

Structure–Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

To discover more potent p97 inhibitors, we carried out a structure–activity relationship study of the quinazoline scaffold previously identified from our HTS campaigns. Two improved inhibitors, ML240 and ML241, inhibit p97 ATPase with IC_(50) values of 100 nM. Both compounds inhibited degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. They also impaired the endoplasmic-reticulum-associated degradation (ERAD) pathway. Unexpectedly, ML240 potently stimulated accumulation of LC3-II within minutes, inhibited cancer cell growth, and rapidly mobilized the executioner caspases 3 and 7, whereas ML241 did not. The behavior of ML240 suggests that disruption of the protein homeostasis function of p97 leads to more rapid activation of apoptosis than is observed with a proteasome inhibitor. Further characterization revealed that ML240 has broad antiproliferative activity toward the NCI-60 panel of cancer cell lines, but slightly lower activity toward normal cells. ML240 also synergizes with the proteasome inhibitor MG132 to kill multiple colon cancer cell lines. Meanwhile, both probes have low off-target activity toward a panel of protein kinases and central nervous system targets. Our results nominate ML240 as a promising starting point for the development of a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97 inhibitors

Universal mounting bracket for laser targeting and feedback system

A support bracket for mounting a device such as a laser targeting and feedback system to a spray gun. The bracket includes a bolt having a threaded end, a first collar disposed on the bolt opposite the threaded end and a second collar threadably engaged with the threaded end of the bolt. A compressible member is disposed on the bolt between the collars. Opposite the compressible member, a support arm used to support the device is attached to the second collar. The bracket is engageable with a portion of the spray gun body and is engaged therewith by deflecting the compressible member between the collars such that the compressible member frictionally engages the spray gun. The use of the compressible member to secure the bracket to the hook allows the bracket to be utilized with spray guns having various configurations so long as the spray gun incorporates a portion on the spray gun body that is engageable by the compressible member

Anti-Müllerian Hormone concentration levels in maternal plasma during the first, second and third trimester of pregnancy

Follicle-Stimulating Hormone (FSH) drops rapidly in pregnancy but Anti-Mullerian Hormone (AMH) has not been shown to drop until about 12 weeks. Since the follicles that secrete AMH are thought to be FSH independent, AMH levels should slowly decline in the absence of FSH because when the follicles reach FSH dependence, they would die off. A study has presented data that suggests a decline in AMH levels suddenly starts at 12 weeks gestation. The present study agrees with a decline in AMH after the first trimester. There is a sharp decline in AMH at 12-16 weeks gestation indicating that the follicular development is actively suppressed, not passively lost because of a drop in FSH. It appears that pregnancy may be a unique situation in regards to AMH

Anti-Müllerian Hormone concentration levels in maternal plasma during the first, second and third trimester of pregnancy

Follicle-Stimulating Hormone (FSH) drops rapidly in pregnancy but Anti-Mullerian Hormone (AMH) has not been shown to drop until about 12 weeks. Since the follicles that secrete AMH are thought to be FSH independent, AMH levels should slowly decline in the absence of FSH because when the follicles reach FSH dependence, they would die off. A study has presented data that suggests a decline in AMH levels suddenly starts at 12 weeks gestation. The present study agrees with a decline in AMH after the first trimester. There is a sharp decline in AMH at 12-16 weeks gestation indicating that the follicular development is actively suppressed, not passively lost because of a drop in FSH. It appears that pregnancy may be a unique situation in regards to AMH

Avalanche dynamics in Bak-Sneppen evolution model observed with standard distribution width of fitness

We introduce the standard distribution width of fitness to characterize the global and individual features of a ecosystem in the Bak-Sneppen evolution model. Through tracking this quantity in evolution, a different hierarchy of avalanche dynamics, $w_{0}$ avalanche is observed. The corresponding gap equation and the self-organized threshold $w_{c}$ are obtained. The critical exponents $\tau ,$ $\gamma$and $\rho$, which describe the behavior of the avalanche size distribution, the average avalanche size and the relaxation to attractor, respectively, are calculated with numerical simulation. The exact master equation and $\gamma$ equation are derived. And the scaling relations are established among the critical exponents of this new avalanche.Comment: 14 pages, 3 figure

Can springs cut canyons into rock?

Amphitheater-headed valleys on Earth and Mars are often assumed to result from erosion by emerging spring water (i.e., seepage erosion or groundwater sapping) rather than by surface runoff. The origin of such valleys has implications for landscape evolution on Earth and the hydrologic cycle and associated potential for life on other planets. In this paper we explore the evidence for seepage erosion in bedrock to address whether valley morphology can be used as a diagnostic indicator of seepage erosion. Seepage erosion is an important process in loose sediment where hydraulic forces cause grain detachment, often resulting in amphitheater-headed valleys. However, the extension of these processes to resistant rock is uncertain. In sedimentary rocks, groundwater might control the shape and rate of valley formation. It is possible, however, that seepage plays only a secondary role to runoff processes. This seems likely in basaltic valleys on Earth, where little evidence exists for seepage erosion. Since the ability of seepage to erode bedrock valleys remains unclear and because many amphitheater-headed valleys were probably carved by other processes, seepage erosion should not be inferred based solely on valley form