COVID-19 Hastalığı ile İlişkili Çoklu Sistemik İnflamatuvar Sendrom Tanılı Çocuk Olguların Değerlendirilmesi

Giriş: Nisan 2020 yılında, SARS-CoV-2 enfeksiyonu geçiren bazı çocuklarda ateş, karın ağrısı, inotrop desteği gerektiren hipotansiyon ve miyokardiyal disfonksiyona yol açan COVID-19 hastalığı ile ilişkili Çoklu Sistemik İnflamatuvar Sendrom(Multisystem Inflammatory Syndrome in Children-MIS-C) olarak adlandırılan hastalık tanımlanmıştır.Bu çalışmada ülkemizde görülen MIS-C tanılı olguların değerlendirilmesi amaçlanmıştır. Materyal-Metod: Bu çalışmada retrospektif olarak Nisan2020-Ağustos2020 tarihleri arasında birden fazla merkezde MIS-C tanısıyla izlenen olguların sosyodemografik, klinik, laboratuvar bulgularıyla tedavi rejimleri ve izlem sonuçları irdelendi. Bulgular: Çalışmaya alınan 29 olgunun 16'sı(%55.2) erkekti ve ortanca yaşları 66 ay(2-208 ay) idi. Olguların 7'si fazla kilolu(vücut kitle indeksi persentili >=%85) olarak değerlendirildi. On bir olguda SARS-CoV-2 RT-PCR pozitifliği, 12'sinde antikor testlerinde pozitiflik saptanırken 4 olguda PCR ve antikor testlerinde pozitiflik görüldü. İki olgunun ise PCR negatif gelmekle birlikte COVID-19 tanılı olguyla temas öyküsü mevcuttu. Olguların tamamında ateş, 22'sinde (%75.9) gastrointestinal semptomlar ve yorgunluk, 20'sinde(%69) döküntü, 17'sinde(%58.6) bulbar konjoktivit ve el-ayaklarda renk değişikliği, 16'sında (%55.2) dudaklarda fissür, 14'ünde (%48.3) kas ağrısı ve çilek dil mevcuttu.Ateş süresinin ortanca değeri 7 (3-17gün) gün saptandı.Olguların 21'inde (%72.4) dehidratasyon, 14'ünde (%48.3) taşikardi, 11'inde hipotansiyon (%37.9) saptandı.Laboratuvar bulgularından ortanca lökosit sayısı 6365 mm³ (3300-31220 mm³), ortanca lenfosit sayısı 1135(570-5800 mm³), ortanca trombosit sayısı 160500 mm³ (46000-747000 mm³) saptandı. Ortalama CRP değeri 165±102 mg/L, ESH değeri 62.6±31.4 mm/s saptandı.Tedavide; olguların 23'üne (%79.3) IVIG, 15'ine (%51.7) asetil salisik asit, 11'ine (%37.9) steroid, 8'ine (%27.6) antikoagülan tedavi uygulandı.Antiviral tedavi 7 (%24.1) olguya uygulandı. 2 olguya tocilizumab tedavisi verildi.Ortanca yatış süreleri 10 gün(1-27) saptanırken 9 olguda yoğun bakım ihtiyacı geliştiği görüldü.3 olgu entübe edildi ve 2 olguda exitus gelişti.Sonuç: MIS-C; yeni tanımlanan, kesin bir tedavisi olmayan hayati tehlikeye neden olabilen organ tutulumu ve şok gelişimine yol açabilecek bir hastalıktır.Çalışmamızda MIS-C olgularında, 3 günden uzun süren ateş, gastrointestinal şikayetler ve yorgunluk en sık görülen yakınmalar olarak belirlendi.COVID-19 pandemi döneminde bu yakınmalarla gelen çocuklarda MIS-C akılda tutulmalı; hızlı tanı ve agresif tedavinin klinik olumlu etkileri unutulmamalıdır

Education of healthcare personnel working with pediatric patients during covid-19 pandemic within the framework of infection control Covid-19 pandemisinde enfeksiyon kontrol çalışmaları çerçevesinde çocuk hastalarla çalışan sağlık personeli eğitimi

© 2020, AVES. All rights reserved.Objective: In the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic caused by SARS-CoV-2, proved to be no exception. Many healthcare workers died in the early stages of pandemic due to inadequate precautions and insufficient protection. It is essential to protect and maintain the safety of healthcare personnel for the confinement of pandemic as well as continuity of qualified healthcare services which is already under strain. Educating healthcare personnel on appropiate use of personal protective equipment (PPE) is as essential as procuring them. Material and Methods: A survey is conducted on 4927 healthcare personnel working solely with pediatric patients from 32 different centers. Education given on PPE usage were questioned and analyzed depending on age, sex, occupation and region. Results: Among four thousand nine hundred twelve healthcare personnel from 32 different centers 91% (n= 4457) received education on PPE usage. Of those who received education only 36% was given both theoretical and applied education. Although there was no differences among different occupation groups, receiving education depended on regions. Conclusion: It is essential to educate healthcare personnel appropiately nationwidely for the continuity of qualified healthcare services during the pandemic

SARS-CoV-2 seropositivity among pediatric health care personnel just after the first peak of pandemic: A nationwide surveillance.

BACKGROUND: COVID-19 pandemic affected every single person on earth one way or the other. The healthcare personnel were no exception, their responsibilities as well as their risks being immense. METHODS: 4927 healthcare personnel all working in pediatric units at 32 hospitals from seven different regions of Turkey enrolled to the study to determine the seroprevalence of SARS Co-V-2 after the first peak wave. Point of care serologic lateral flow rapid test kit for IgM/IgG was used (Ecotest CE Assure Tech. Co. Ltd.). Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed. RESULTS: Nearly 6.1% of healthcare personnel were found to be seropositive for SARS Co-V- 2. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19 co-worker increased the likelihood of infection. The least and the most experienced personnel affected more. Most of the seropositive healthcare personnel (68%) did not have any suspicion that they had COVID-19 previously. CONCLUSIONS: Health surveillance for healthcare personnel involving routine point-of-care nucleic acid testing as well as monitoring PPE adherence would be important strategies to protect healthcare personnel from COVID-19 and to reduce nosocomial SARS-CoV-2 transmission

Evaluation of vaccination status of health care workers for recommended vaccines and their acceptance of SARS-CoV-2 vaccines

© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.Introduction: Health care workers (HCWs) are disproportionately exposed to infectious diseases and play a role in nosocomial transmission, making them a key demographic for vaccination. HCW vaccination rates are not optimal in many countries; hence, compulsory vaccination policies have been implemented in some countries. Although these policies are effective and necessary under certain conditions, resolving HCWs’ hesitancies and misconceptions about vaccines is crucial. HCWs have the advantage of direct contact with patients; hence, they can respond to safety concerns, explain the benefits of vaccination, and counter antivaccine campaigns that escalate during pandemics, as has been observed with COVID-19. Method: A short survey was carried out in May–June 2020 on the vaccination status of HCWs working with pediatric patients with COVID-19. The survey inquired about their vaccination status (mumps/measles/rubella [MMR], varicella, influenza, and diphtheria/tetanus [dT]) and willingness to receive hypothetical future COVID-19 vaccines. The respondents were grouped according to gender, age, occupation, and region. Results: In total, 4927 HCWs responded to the survey. Most were young, healthy adults. The overall vaccination rates were 57.8% for dT in the past 10 years, 44.5% for MMR, 33.2% for varicella, and 13.5% for influenza. Vaccination rates were the highest among physicians. The majority of HCWs (81%) stated that they would be willing to receive COVID-19 vaccines. Conclusion: Although vaccination rates for well-established vaccines were low, a majority of HCWs were willing to receive COVID-19 vaccines when available. Education and administrative trust should be enhanced to increase vaccination rates among HCWs