366 research outputs found

    Marshall Community Trans Clothing Closet

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    In the United States it is estimated that 1.4 million adults are transgender (Flores, Herman, Gates, & Brown, 2016), and West Virginia leads the country with the largest number of teens, 13-17 years of age, who identify as transgender (1.04%; Herman, Flores, Brown, Williams, & Conron, 2017). Many transgender teens are financially cut off by their families (Lambda Legal, 2017), and transgender Americans are four times more likely than the general population to report a household income of less than $10,000 (Center for American Progress, 2015). This is especially concerning because 87% of transgender individuals report having completed at least some college, and 47% have earned a college degree (Center for American Progress, 2015). On college campuses 41% of transgender students are estimated to be harassed, but only 28% report the harassment which lays the groundwork for the need for acceptance and visibility on campuses (Dugan, Kusel, & Simounet, 2012 ). A study at the University of Michigan suggested that transgender students report educational barriers on college campuses, including inadequate support for transgender students in terms of health care and counseling provided by the college (Matney, 2003). The current project seeks to place collection bins on Marshall University’s campus for clothing for transgender students. After the collection, the closet will enable an experience where those who identify as part of the LGBT community will be able to comfortably explore their gender identity in various ways in a safe place. Specifically, we will have clothes for them to try on and peers to support and talk with each other. Most of all, this experience will establish a lasting atmosphere of acceptance and a closet in the LGBT office which will always be ready for use for years to come

    How to prepare fruits and vegetables for freezing : with suggestions for choosing suitable varieties

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    Mechanical thrombectomy in patients with acute ischemic stroke: a cost-effectiveness and value of implementation analysis

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    Background: Recent clinical trials have demonstrated the efficacy of mechanical thrombectomy in acute ischemic stroke. Aims: To determine the cost-effectiveness, value of future research, and value of implementation of mechanical thrombectomy. Methods: Using UK clinical and cost data from the Pragmatic Ischemic Stroke Thrombectomy Evaluation (PISTE) trial, we estimated the cost-effectiveness of mechanical thrombectomy over time horizons of 90-days and lifetime, based on a decision-analytic model, using all existing evidence. We performed a meta-analysis of seven clinical trials to estimate treatment effects. We used sensitivity analysis to address uncertainty. Value of implementation analysis was used to estimate the potential value of additional implementation activities to support routine delivery of mechanical thrombectomy. Results: Over the trial period (90 days), compared with best medical care alone, mechanical thrombectomy incurred an incremental cost of £5207 and 0.025 gain in QALY (incremental cost-effectiveness ratio (ICER) £205,279), which would not be considered cost-effective. However, mechanical thrombectomy was shown to be cost-effective over a lifetime horizon, with an ICER of £3466 per QALY gained. The expected value of perfect information per patient eligible for mechanical thrombectomy in the UK is estimated at £3178. The expected value of full implementation of mechanical thrombectomy is estimated at £1.3 billion over five years. Conclusion: Mechanical thrombectomy was cost-effective compared with best medical care alone over a patient’s lifetime. On the assumption of 30% implementation being achieved throughout the UK healthcare system, we estimate that the population health benefits obtained from this treatment are greater than the cost of implementation. Trial registration: NCT01745692

    The Expanded City - Stage One

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    The Expanded City is a three-stage project, which investigates the changing nature of cities. During the last decade, urban development was largely concerned with transforming post-industrial city centres into retail and residential developments. However, projects such as Preston’s City Deal scheme – part of a national initiative to encourage economic growth in key cities across England – increasingly involve building cities from the outside in. For 10 years In Certain Places has focused on and shaped developments within the city centre of Preston. The Expanded City extends the methods and approaches refined over the last decade to new contexts and locations; the city’s edges. What are the contributions artists can make to the external perceptions and internal experiences of inner city and suburban places? How can that inform debate about the imminent future of these places in terms of urban planning and cultural provision? Following an invitation by Preston City Council, In Certain Places has been working with commissioned artists Olivia Keith, Gavin Renshaw, Emily Speed and duo Ian Nesbitt and Ruth Levene, and The Decorators. The artists have investigated the physical and cultural topography of the outskirts of Preston, ‘deep mapping’ the areas marked for growth. Through a focus on the practical and political aspects of issues such as housing, play and leisure provision, transport infrastructure, emotional connections to the land, and environmental stewardship, the artists have developed projects which raise questions about and offer suggestions for the future of Preston and other expanding cities. All the artists share an interest in boundaries, routes, edges and the urban/rural binary, and work across a range of media, including film, photography and performance. The commissions will explore the social and physical aspects of the places, their relationships with the city centre and the potential implications of planned developments. Writer and curator Lauren Velvick contextualised and provided a critical narrative for the development of the work of the artists in a regular Expanded City blog. Stage one beginning in 2016 saw the beginning of research and development. The work of this first phase is summarised in the 2016 publication produced by Lauren Velvick, the project's ‘writer in residence’. The publication contextualised and provided a critical narrative for the development of the artists’ work. This phase also saw the Expanded City Symposium. The symposium which took place in Woodplumpton and District Club in the north of Preston, presented the first stage of research in the Expanded City project. Alongside presentations about urban demographics by economist Paul Swinney, the production of community spaces by design collective The Decorators, and a performance lecture by Ian Nesbitt and Ruth Levene, the day included a bus trip around the City Deal areas, where Gavin Renshaw, Olivia Keith and Lauren Velvick presented their work-in-progress

    Mythology and the Movies, Vol. 1

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    In this course, Mythology and the Movies, students were assigned the creation of a four page comic book. Many of the students were unfamiliar with comic books but learned in the class how the visual sequence of images in a comic is very much like that in a movie. The project had to use either the Harry Potter movies or the Twilight movies as the basis for an original myth that investigated a mythological theme: chaos, creation, time, the quest, metamorphosis, difference, or the Other . Each comic was an exercise in rethinking these universes and using the characters and setting in a new, mythological context.https://repository.upenn.edu/showcase_comics/1023/thumbnail.jp

    An alternative strategy for trypanosome survival in the mammalian bloodstream revealed through genome and transcriptome analysis of the ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri

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    There are hundreds of Trypanosoma species that live in the blood and tissue spaces of their vertebrate hosts. The vast majority of these do not have the ornate system of antigenic variation that has evolved in the small number of African trypanosome species, but can still maintain long term infections in the face of the vertebrate adaptive immune system. Trypanosoma theileri is a typical example, it has a restricted host range of cattle and other Bovinae and is only occasionally reported to cause patent disease although no systematic survey of the effect of infection on agricultural productivity has been performed. Here, a detailed genome sequence and a transcriptome analysis of gene expression in bloodstream form T. theileri have been performed. Analysis of the genome sequence and expression showed that T. theileri has a typical kinetoplastid genome structure and allowed a prediction that it is capable of meiotic exchange, gene silencing via RNA interference and, potentially, density-dependent growth control. In particular, the transcriptome analysis has allowed a comparison of two distinct trypanosome cell surfaces, T. brucei and T. theileri, that have each evolved to enable the maintenance of a long-term extracellular infection in cattle. The T. theileri cell surface can be modelled to contain a mixture of proteins encoded by four novel large and divergent gene families and by members of a major surface protease gene family. This surface composition is distinct from the uniform variant surface glycoprotein coat on African trypanosomes providing an insight into a second mechanism used by trypanosome species that proliferate in an extracellular milieu in vertebrate hosts to avoid the adaptive immune response

    The Grizzly, March 29, 2012

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    Airband Benefits Crime Victims Center • Blues Writer Sharon Bridgforth Reads Work • Gilmore Visits Berman Art Museum • UC Recyclemania Holds Green Day Carnival • Alabama Civil Rights Trip was Living History for Students • Rosati Embraces Opportunity at Frederick Living • Greek Week in Progress, Helps to Unite UC Sororities and Fraternities • Opinion: Trayvon Martin Case is a Wake-Up Call • Ursinus Celebrates St. Patrick\u27s Weekend • Player Spotlight: Amanda Laurito, Track and Field • Rugby Continues Building Tradition • Senior Spotlight: Jeff Ocampo, Men\u27s Lacrossehttps://digitalcommons.ursinus.edu/grizzlynews/1856/thumbnail.jp

    THE EXPANDED CITY - STAGE TWO

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    For 10 years In Certain Places has focused on and shaped developments within the city centre of Preston. The Expanded City is a three-stage programme of artistic research, interventions and events, designed to inform a series of planned infrastructure projects on the outskirts of Preston. Part of Preston’s ‘City Deal’ – a central government initiative which aims to encourage economic growth by addressing strategic infrastructure challenges – the scheme includes the creation of over 17,000 houses as well as new roads and amenities. In the first stage of The Expanded City project (2015-2016) commissioned artists Olivia Keith, Gavin Renshaw, Emily Speed and duo Ian Nesbitt and Ruth Levene investigated the physical and cultural topography of the outskirts of Preston, ‘deep mapping’ the areas marked for growth. The artists share an interest in boundaries, routes, edges and the urban/rural binary, and work across a range of media, including film, photography and performance. This second phase running from 2017 until 2018 was a continuation of the artists' active research and saw the project expand with a series of Network events which brought external perspectives from experts and local communities directly into the development of the artists’ work. These included; Ruth Levene and Ian Nesbitt's 'Precarious Landscape Bus Tour' with archaeologist Bob Johnston; Gavin Renshaw's 'Routes in, Routes Out' in conversation event with cycling journalist Jack Thurston; Olivia Keith two week residency at the Final Whistle Cafe in Cottam culminating in a workshop 'Traces of Place'; Emily Speed's in conversation event with architect Lee Ivett on the topic of playspace 'What do we need in a Space for Play?'; and Lauren Velvick's 'Open House' event, an informal evening of music and discussion about the politics and practicalities of housing, leading to the creation of an 'Open House' publication. The second phase featured the 'Lie of the Land' symposium, a day of artworks, presentations and conversations, which drew on research undertaken by the artists to explore how our everyday lives are shaped by the ownership, management and development of land. The symposium featured talks by Peter Hetherington – journalist and author of the book 'Whose Land is Our Land: The use and abuse of Britain’s forgotten acres', and Julia Heslop – a Newcastle-based artist whose self-build housing project, 'Protohome' (2016), examined participatory alternatives to mainstream housing provision. The event also included a bus tour to sites in and around Preston, during which The Expanded City artists presented their research into issues of housing, cycling infrastructure and the changing landscape. The symposium was accompanied by 'The Expanded City Map' created by artist Claire Tindale. The map geographically locates and gives details of the main research insights generated through the projects by the commissioned artists This phase saw the finalisation by The Decorators of two pieces emerging from their research the 'Learning from Preston' report and the 'Garstang Road Stories' audio artwork. (https://podtail.com/en/podcast/the-decorators-on-air/garstang-road-stories/) Ruth Levene and Ian Nesbitt's research culminated in May 2018 with them curating 'Notes from a Precarious Landscape' – a community exhibition curated by in a vacant house in a new development in Cottam, North Preston, which included contributions from residents of Preston and its surrounding villages. The exhibition explored the ways in which the land around the city is changing or has changed in the past. Emily Speed’s research in phase two of The Expanded City culminated in the project ‘Model Village?’ in June 2018, during which she worked with members of the public, including local residents and school pupils of all ages to construct a temporary model village on the site of a housing development. Participants were asked ‘What would your dream place to live or play in look like?’ and had the opportunity to use coloured clay to build their ideal home, and make a mark on the village by creating, extending, squashing or customising its buildings, trees, parks and streets. Gavin Renshaw's research in this phase concluded with the production of a cycling map for Preston which collates routes, information relevant to cyclists, such as storage, topography and traffic black spots, and existing cycle infrastructure within a single, visual inventory. Olivia Keith's project 'Traces of Place' involved a two-week residency at the Final Whistle Café in Cottam during the summer of 2017, in which she collated memories and contributions from local people.. As a direct result of her work and the conversations hosted, Olivia was invited to contribute to the 'Streets of Change: Beattie’s Preston and Beyond' exhibition at the Harris Museum and Art Gallery, where she created 'Setting in Place: The Making of a Jellied Map of Nether Bartle' a performance installation in two separate venues, Bartle Hall and Harris Museum & Art Gallery, Preston. Another outcome from her research was the creation of a linocut 'Nether Bartle map' as a prompt for discussions around naming and place. The Expanded City has been developed in response to an invitation from Preston City Council, to inform a programme of infrastructure projects on the outskirts of the city proposed by a £430m City Deal scheme. The City Deal scheme aims to deliver new jobs and housing, by addressing strategic transport, environmental, community and cultural infrastructure challenges
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