1,008 research outputs found
How the asymmetry of internal potential influences the shape of I-V characteristic of nanochannels
Ion transport in biological and synthetic nanochannels is characterized by
such phenomena as ion current fluctuations, rectification, and pumping.
Recently, it has been shown that the nanofabricated synthetic pores could be
considered as analogous to biological channels with respect to their transport
characteristics \cite{Apel, Siwy}. The ion current rectification is analyzed.
Ion transport through cylindrical nanopores is described by the Smoluchowski
equation. The model is considering the symmetric nanopore with asymmetric
charge distribution. In this model, the current rectification in asymmetrically
charged nanochannels shows a diode-like shape of characteristic. It is
shown that this feature may be induced by the coupling between the degree of
asymmetry and the depth of internal electric potential well. The role of
concentration gradient is discussed
Response to sub-threshold stimulus is enhanced by spatially heterogeneous activity
Sub-threshold stimuli cannot initiate excitations in active media, but
surprisingly as we show in this paper, they can alter the time-evolution of
spatially heterogeneous activity by modifying the recovery dynamics. This
results in significant reduction of waveback velocity which may lead to spatial
coherence, terminating all activity in the medium including spatiotemporal
chaos. We analytically derive model-independent conditions for which such
behavior can be observed.Comment: 5 pages, 5 figure
Convective Fingering of an Autocatalytic Reaction Front
We report experimental observations of the convection-driven fingering
instability of an iodate-arsenous acid chemical reaction front. The front
propagated upward in a vertical slab; the thickness of the slab was varied to
control the degree of instability. We observed the onset and subsequent
nonlinear evolution of the fingers, which were made visible by a {\it p}H
indicator. We measured the spacing of the fingers during their initial stages
and compared this to the wavelength of the fastest growing linear mode
predicted by the stability analysis of Huang {\it et. al.} [{\it Phys. Rev. E},
{\bf 48}, 4378 (1993), and unpublished]. We find agreement with the thickness
dependence predicted by the theory.Comment: 11 pages, RevTex with 3 eps figures. To be published in Phys Rev E,
[email protected], [email protected], [email protected]
Avalanche of Bifurcations and Hysteresis in a Model of Cellular Differentiation
Cellular differentiation in a developping organism is studied via a discrete
bistable reaction-diffusion model. A system of undifferentiated cells is
allowed to receive an inductive signal emenating from its environment.
Depending on the form of the nonlinear reaction kinetics, this signal can
trigger a series of bifurcations in the system. Differentiation starts at the
surface where the signal is received, and cells change type up to a given
distance, or under other conditions, the differentiation process propagates
through the whole domain. When the signal diminishes hysteresis is observed
Dynamics of lattice spins as a model of arrhythmia
We consider evolution of initial disturbances in spatially extended systems
with autonomous rhythmic activity, such as the heart. We consider the case when
the activity is stable with respect to very smooth (changing little across the
medium) disturbances and construct lattice models for description of
not-so-smooth disturbances, in particular, topological defects; these models
are modifications of the diffusive XY model. We find that when the activity on
each lattice site is very rigid in maintaining its form, the topological
defects - vortices or spirals - nucleate a transition to a disordered,
turbulent state.Comment: 17 pages, revtex, 3 figure
Renormalization Group Theory for a Perturbed KdV Equation
We show that renormalization group(RG) theory can be used to give an analytic
description of the evolution of a perturbed KdV equation. The equations
describing the deformation of its shape as the effect of perturbation are RG
equations. The RG approach may be simpler than inverse scattering theory(IST)
and another approaches, because it dose not rely on any knowledge of IST and it
is very concise and easy to understand. To the best of our knowledge, this is
the first time that RG has been used in this way for the perturbed soliton
dynamics.Comment: 4 pages, no figure, revte
Incorporating Inductances in Tissue-Scale Models of Cardiac Electrophysiology
In standard models of cardiac electrophysiology, including the bidomain and
monodomain models, local perturbations can propagate at infinite speed. We
address this unrealistic property by developing a hyperbolic bidomain model
that is based on a generalization of Ohm's law with a Cattaneo-type model for
the fluxes. Further, we obtain a hyperbolic monodomain model in the case that
the intracellular and extracellular conductivity tensors have the same
anisotropy ratio. In one spatial dimension, the hyperbolic monodomain model is
equivalent to a cable model that includes axial inductances, and the relaxation
times of the Cattaneo fluxes are strictly related to these inductances. A
purely linear analysis shows that the inductances are negligible, but models of
cardiac electrophysiology are highly nonlinear, and linear predictions may not
capture the fully nonlinear dynamics. In fact, contrary to the linear analysis,
we show that for simple nonlinear ionic models, an increase in conduction
velocity is obtained for small and moderate values of the relaxation time. A
similar behavior is also demonstrated with biophysically detailed ionic models.
Using the Fenton-Karma model along with a low-order finite element spatial
discretization, we numerically analyze differences between the standard
monodomain model and the hyperbolic monodomain model. In a simple benchmark
test, we show that the propagation of the action potential is strongly
influenced by the alignment of the fibers with respect to the mesh in both the
parabolic and hyperbolic models when using relatively coarse spatial
discretizations. Accurate predictions of the conduction velocity require
computational mesh spacings on the order of a single cardiac cell. We also
compare the two formulations in the case of spiral break up and atrial
fibrillation in an anatomically detailed model of the left atrium, and [...].Comment: 20 pages, 12 figure
Limit theorems for weakly subcritical branching processes in random environment
For a branching process in random environment it is assumed that the
offspring distribution of the individuals varies in a random fashion,
independently from one generation to the other. Interestingly there is the
possibility that the process may at the same time be subcritical and,
conditioned on nonextinction, 'supercritical'. This so-called weakly
subcritical case is considered in this paper. We study the asymptotic survival
probability and the size of the population conditioned on non-extinction. Also
a functional limit theorem is proven, which makes the conditional
supercriticality manifest. A main tool is a new type of functional limit
theorems for conditional random walks.Comment: 35 page
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ATLAS Inner Detector Event Data Model
The data model for event reconstruction (EDM) in the Inner Detector of the ATLAS experiment is presented. Different data classes represent evolving stages in the reconstruction data flow, and specific derived classes exist for the sub-detectors. The Inner Detector EDM also extends the data model for common tracking in ATLAS and is integrated into the modular design of the ATLAS high-level trigger and off-line software
Finite-gap Solutions of the Vortex Filament Equation: Isoperiodic Deformations
We study the topology of quasiperiodic solutions of the vortex filament
equation in a neighborhood of multiply covered circles. We construct these
solutions by means of a sequence of isoperiodic deformations, at each step of
which a real double point is "unpinched" to produce a new pair of branch points
and therefore a solution of higher genus. We prove that every step in this
process corresponds to a cabling operation on the previous curve, and we
provide a labelling scheme that matches the deformation data with the knot type
of the resulting filament.Comment: 33 pages, 5 figures; submitted to Journal of Nonlinear Scienc
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