160 research outputs found

    Higgs-photon resonances

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    We study models that produce a Higgs boson plus photon (h0γh^0 \gamma) resonance at the LHC. When the resonance is a Z′Z' boson, decays to h0γh^0 \gamma occur at one loop. If the Z′Z' boson couples at tree-level to quarks, then the h0γh^0 \gamma branching fraction is typically of order 10−510^{-5} or smaller. Nevertheless, there are models that would allow the observation of Z′→h0γZ' \to h^0 \gamma at s=13\sqrt{s} = 13 TeV with a cross section times branching fraction larger than 1 fb for a Z′Z' mass in the 200--450 GeV range, and larger than 0.1 fb for a mass up to 800 GeV. The 1-loop decay of the Z′Z' into lepton pairs competes with h0γh^0 \gamma, even if the Z′Z' couplings to leptons vanish at tree level. We also present a model in which a Z′Z' boson decays into a Higgs boson and a pair of collimated photons, mimicking an h0γh^0 \gamma resonance. In this model, the h0γh^0 \gamma resonance search would be the discovery mode for a Z′Z' as heavy as 2 TeV. When the resonance is a scalar, although decay to h0γh^0 \gamma is forbidden by angular momentum conservation, the h0h^0 plus collimated photons channel is allowed. We comment on prospects of observing an h0γh^0 \gamma resonance through different Higgs decays, on constraints from related searches, and on models where h0h^0 is replaced by a nonstandard Higgs boson.Comment: 22 page

    An engineered Tetrahymena tRNA(Gln) for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression

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    A new tRNA, THG73, has been designed and evaluated as a vehicle for incorporating unnatural amino acids site-specifically into proteins expressed in vivo using the stop codon suppression technique. The construct is a modification of tRNAGln(CUA) from Tetrahymena thermophila, which naturally recognizes the stop codon UAG. Using electrophysiological studies of mutations at several sites of the nicotinic acetylcholine receptor, it is established that THG73 represents a major improvement over previous nonsense suppressors both in terms of efficiency and fidelity of unnatural amino acid incorporation. Compared with a previous tRNA used for in vivo suppression, THG73 is as much as 100-fold less likely to be acylated by endogenous synthetases of the Xenopus oocyte. This effectively eliminates a major concern of the in vivo suppression methodology, the undesirable incorporation of natural amino acids at the suppression site. In addition, THG73 is 4-10-fold more efficient at incorporating unnatural amino acids in the oocyte system. Taken together, these two advances should greatly expand the range of applicability of the in vivo nonsense suppression methodology

    Development of utility system simulation model

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    "Worked preformed for Commonwealth Edison Company, Chicago, Illinois."Includes bibliographical references (leaf 28)MIT DSR Project 7210

    Simulation and optimization techniques of nuclear in-core fuel management decisions

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    Also issued as a Ph. D. thesis in the Dept. of Nuclear Engineering, MIT, 1973Includes bibliographical references (leves 290-293)M.I.T. DSR Project no. 72107Work sponsored by Commonwealth Edison Company, Chicago, Illinoi

    EUV mask reflectivity measurements with micron-scale spatial resolution

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    The effort to produce defect-free mask blanks for EUV lithography relies on increasing the detection sensitivity of advanced mask inspection tools, operating at several wavelengths. We describe the unique measurement capabilities of a prototype actinic (EUV wavelength) microscope that is capable of detecting small defects and reflectivity changes that occur on the scale of microns to nanometers. Types of defects: (a) Buried Substrate Defects: particles & pits (causes amplitude and/or phase variations); (b) Surface Contamination (reduces reflectivity and (possibly) contrast); (c) Damage from Inspection and Use (reduces the reflectivity of the multilayer coating). This paper presents an overview of several topics where scanning actinic inspection makes a unique contribution to EUVL research. We describe the role of actinic scanning inspection in four cases: defect repair studies; observations of laser damage; after scanning electron microscopy; and native and programmed defects

    The importance of both setting and intensity of physical activity in relation to non-clinical anxiety and depression

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    Physical activity is associated with good physical and mental health. Current recommendations suggest that people should achieve 30 minutes of moderate-intensity activity most days of the week to gain health benefits. This activity may be accumulated in leisure time, in active commuting, at work or in the home. Here we look at the cross-sectional relationship between physical activity and mental health as measured by the HADS anxiety and depression scores in a sample of 1,742 participants from a Scottish general population survey. The participants were men and women in three age cohorts aged around 24, 44 and 64 years who, in 1995, were interviewed face to face and also self-completed the HADS depression and anxiety scale. Respondents reported their levels of physical activity at work, in the home and in leisure time; the intensities of activity were also determined. Physical activity was related to depression scores but not to anxiety scores. There was no relationship between work physical activity and depression score. Among women, depression score increased with each additional episode of vigorous home activity. In both sexes, depression score decreased with each additional episode of vigorous leisure activity, but among men the decrease in depression score with moderate leisure activity was reversed if a lot of moderate activity was undertaken. We have found a variable relationship between depression scores and various settings for physical activity. Researchers, policymakers and practitioners who are interested in the relationship between physical activity and mental health should take into account the setting for activity as well as frequency, duration and intensity of activity
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