524 research outputs found
Operator Manifold Approach to Geometry and Particle Physics
The question that guides our discussion is how did the geometry and particles
come into being. The present theory reveals primordial deeper structures
underlying fundamental concepts of contemporary physics. We begin with a
drastic revision of a role of local internal symmetries in physical concept of
curved geometry. A standard gauge principle of local internal symmetries is
generalized. The gravitation gauge group is proposed, which is generated by
hidden local internal symmetries. Last two parts address to the question of
physical origin of geometry and basic concepts of particle physics such as the
fields of quarks with the spins and various quantum numbers, internal
symmetries and so forth; also four basic principles of Relativity, Quantum,
Gauge and Color Confinement, which are, as it was proven, all derivative and
come into being simultaneously. The most promising aspect of our approach so
far is the fact that many of the important anticipated properties, basic
concepts and principles of particle physics are appeared quite naturally in the
framework of suggested theory.Comment: LaTex, 42 pages, email [email protected]
Gravitation and inertia; a rearrangement of vacuum in gravity
We address the gravitation and inertia in the framework of 'general gauge
principle', which accounts for 'gravitation gauge group' generated by hidden
local internal symmetry implemented on the flat space. We connect this group to
nonlinear realization of the Lie group of 'distortion' of local internal
properties of six-dimensional flat space, which is assumed as a toy model
underlying four-dimensional Minkowski space. The agreement between proposed
gravitational theory and available observational verifications is satisfactory.
We construct relativistic field theory of inertia and derive the relativistic
law of inertia. This theory furnishes justification for introduction of the
Principle of Equivalence. We address the rearrangement of vacuum state in
gravity resulting from these ideas.Comment: 17 pages, no figures, revtex4, Accepted for publication in Astrophys.
Space Sc
Star Formation and Tidal Encounters with the Low Surface Brightness Galaxy UGC 12695 and Companions
We present VLA H I observations of the low surface brightness galaxy UGC
12695 and its two companions, UGC 12687 and a newly discovered dwarf galaxy
2333+1234. UGC 12695 shows solid body rotation but has a very lopsided
morphology of the H I disk, with the majority of the H I lying in the southern
arm of the galaxy. The H I column density distribution of this very blue, LSB
galaxy coincides in detail with its light distribution. Comparing the H I
column density of UGC 12695 with the empirical (but not well understood) value
of Sigma_c = 10E21 atoms/cm^2 found in, i.e., Skillman's 1986 paper shows the
star formation to be a local affair, occurring only in those regions where the
column density is above this star formation threshold. The low surface
brightness nature of this galaxy could thus be attributed to an insufficient
gas surface density, inhibiting star formation on a more global scale.
Significantly, though, the Toomre criterion places a much lower critical
density on the galaxy (+/-10E20 atoms/cm^2), which is shown by the galaxy's low
SFR to not be applicable.
Within a projected distance of 300kpc/30kms of UGC 12695 lie two companion
galaxies - UGC 12687, a high surface brightness barred spiral galaxy, and
2333+1234, a dwarf galaxy discovered during this investigation. The close
proximity of the three galaxies, combined with UGC 12695's extremely blue color
and regions of localized starburst and UGC 12687's UV excess bring to mind
mutually induced star formation through tidal activity.Comment: 14 pages, 8 figures (2 color), To be published in A.J., May 2000
A comparison between gravimetric and in-situ spectroscopic methods to measure the sorption of COâ‚‚in a biocompatible polymer
In situ ATR-IR spectroscopy was used to simultaneously measure the sorption and swelling of carbon dioxide at high pressures in a biocompatible
acrylate copolymer poly(methylmethacrylate-co-ethylhexylacrylate-co-ethyleneglycoldimethacrylate), P(MMA–EHA–EGDMA).
The ν3 band of CO2 dissolved in the polymer (at 2335 cm−1) was used to calculate the sorption data and the polymer swelling was determined
by analyzing the changes in the absorbance of the ν(C O) band (at 1730 cm−1) of the polymer. Transmission spectroscopy in the near-IR
region was also used to study the sorption of CO2 in the polymer using combinational and overtone bands. The experiments were carried out
in a pressure range of 2.0–12.0MPa and in a temperature range of 27–40 ◦C. The data for CO2 sorption in this polymer obtained by in situ
spectroscopic methods have been compared to the data obtained by the gravimetric technique
The electron electric dipole moment enhancement factors of Rubidium and Caesium atoms
The enhancement factors of the electric dipole moment (EDM) of the ground
states of two paramagnetic atoms; rubidium (Rb) and caesium (Cs) which are
sensitive to the electron EDM are computed using the relativistic
coupled-cluster theory and our results are compared with the available
calculations and measurements. The possibility of improving the limit for the
electron EDM using the results of our present work is pointed out.Comment: AISAMP7 Conference paper, Accepted in Journal of Physics: Conference
Series: 200
Attenuated total reflection-FT-IR spectroscopic imaging of protein crystallization
Protein crystallization is of strategic and commercial relevance in the post-genomic era because of its pivotal role in structural proteomics projects. Although protein structures are crucial for understanding the function of proteins and to the success of rational drug design and other biotechnology applications, obtaining high quality crystals is a major bottleneck to progress. The major means of obtaining crystals is by massive-scale screening of a target protein solution with numerous crystallizing agents. However, when crystals appear in these screens, one cannot easily know if they are crystals of protein, salt, or any other molecule that happens to be present in the trials. We present here a method based on Attenuated Total Reflection (ATR)-FT-IR imaging that reliably identifies protein crystals through a combination of chemical specificity and the visualizing capability of this approach, thus solving a major hurdle in protein crystallization. ATR-FT-IR imaging was successfully applied to study the crystallization of thaumatin and lysozyme in a high-throughput manner, simultaneously from six different solutions. This approach is fast as it studies protein crystallization in situ and provides an opportunity to examine many different samples under a range of conditions
Glucocorticoids Rapidly Activate cAMP Production via G\u3csub\u3eαs\u3c/sub\u3e to Initiate Non-Genomic Signaling That Contributes to One-Third of Their Canonical Genomic Effects
Glucocorticoids are widely used for the suppression of inflammation, but evidence is growing that they can have rapid, non-genomic actions that have been unappreciated. Diverse cell signaling effects have been reported for glucocorticoids, leading us to hypothesize that glucocorticoids alone can swiftly increase the 3′,5′-cyclic adenosine monophosphate (cAMP) production. We found that prednisone, fluticasone, budesonide, and progesterone each increased cAMP levels within 3 minutes without phosphodiesterase inhibitors by measuring real-time cAMP dynamics using the cAMP difference detector in situ assay in a variety of immortalized cell lines and primary human airway smooth muscle (HASM) cells. A membrane- impermeable glucocorticoid showed similarly rapid stimulation of cAMP, implying that responses are initiated at the cell surface. siRNA knockdown of Gαs virtually eliminated glucocorticoidstimulated cAMP responses, suggesting that these drugs activate the cAMP production via a G protein-coupled receptor. Estradiol had small effects on cAMP levels but G protein estrogen receptor antagonists had little effect on responses to any of the glucocorticoids tested. The genomic and non-genomic actions of budesonide were analyzed by RNA-Seq analysis of 24 hours treated HASM, with and without knockdown of Gαs. A 140-gene budesonide signature was identified, of which 48 genes represent a non-genomic signature that requires Gαs signaling. Collectively, this non-genomic cAMP signaling modality contributes to one-third of the gene expression changes induced by glucocorticoid treatment and shifts the view of how this important class of drugs exerts its effect
From Hurwitz numbers to Kontsevich-Witten tau-function: a connection by Virasoro operators
In this letter,we present our conjecture on the connection between the
Kontsevich--Witten and the Hurwitz tau-functions. The conjectural formula
connects these two tau-functions by means of the group element. An
important feature of this group element is its simplicity: this is a group
element of the Virasoro subalgebra of . If proved, this conjecture
would allow to derive the Virasoro constraints for the Hurwitz tau-function,
which remain unknown in spite of existence of several matrix model
representations, as well as to give an integrable operator description of the
Kontsevich--Witten tau-function.Comment: 13 page
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