Star Formation and Tidal Encounters with the Low Surface Brightness Galaxy UGC 12695 and Companions

We present VLA H I observations of the low surface brightness galaxy UGC 12695 and its two companions, UGC 12687 and a newly discovered dwarf galaxy 2333+1234. UGC 12695 shows solid body rotation but has a very lopsided morphology of the H I disk, with the majority of the H I lying in the southern arm of the galaxy. The H I column density distribution of this very blue, LSB galaxy coincides in detail with its light distribution. Comparing the H I column density of UGC 12695 with the empirical (but not well understood) value of Sigma_c = 10E21 atoms/cm^2 found in, i.e., Skillman's 1986 paper shows the star formation to be a local affair, occurring only in those regions where the column density is above this star formation threshold. The low surface brightness nature of this galaxy could thus be attributed to an insufficient gas surface density, inhibiting star formation on a more global scale. Significantly, though, the Toomre criterion places a much lower critical density on the galaxy (+/-10E20 atoms/cm^2), which is shown by the galaxy's low SFR to not be applicable. Within a projected distance of 300kpc/30kms of UGC 12695 lie two companion galaxies - UGC 12687, a high surface brightness barred spiral galaxy, and 2333+1234, a dwarf galaxy discovered during this investigation. The close proximity of the three galaxies, combined with UGC 12695's extremely blue color and regions of localized starburst and UGC 12687's UV excess bring to mind mutually induced star formation through tidal activity.Comment: 14 pages, 8 figures (2 color), To be published in A.J., May 2000

Gravitation and inertia; a rearrangement of vacuum in gravity

We address the gravitation and inertia in the framework of 'general gauge principle', which accounts for 'gravitation gauge group' generated by hidden local internal symmetry implemented on the flat space. We connect this group to nonlinear realization of the Lie group of 'distortion' of local internal properties of six-dimensional flat space, which is assumed as a toy model underlying four-dimensional Minkowski space. The agreement between proposed gravitational theory and available observational verifications is satisfactory. We construct relativistic field theory of inertia and derive the relativistic law of inertia. This theory furnishes justification for introduction of the Principle of Equivalence. We address the rearrangement of vacuum state in gravity resulting from these ideas.Comment: 17 pages, no figures, revtex4, Accepted for publication in Astrophys. Space Sc

The electron electric dipole moment enhancement factors of Rubidium and Caesium atoms

The enhancement factors of the electric dipole moment (EDM) of the ground states of two paramagnetic atoms; rubidium (Rb) and caesium (Cs) which are sensitive to the electron EDM are computed using the relativistic coupled-cluster theory and our results are compared with the available calculations and measurements. The possibility of improving the limit for the electron EDM using the results of our present work is pointed out.Comment: AISAMP7 Conference paper, Accepted in Journal of Physics: Conference Series: 200

Attenuated total reflection-FT-IR spectroscopic imaging of protein crystallization

Protein crystallization is of strategic and commercial relevance in the post-genomic era because of its pivotal role in structural proteomics projects. Although protein structures are crucial for understanding the function of proteins and to the success of rational drug design and other biotechnology applications, obtaining high quality crystals is a major bottleneck to progress. The major means of obtaining crystals is by massive-scale screening of a target protein solution with numerous crystallizing agents. However, when crystals appear in these screens, one cannot easily know if they are crystals of protein, salt, or any other molecule that happens to be present in the trials. We present here a method based on Attenuated Total Reflection (ATR)-FT-IR imaging that reliably identifies protein crystals through a combination of chemical specificity and the visualizing capability of this approach, thus solving a major hurdle in protein crystallization. ATR-FT-IR imaging was successfully applied to study the crystallization of thaumatin and lysozyme in a high-throughput manner, simultaneously from six different solutions. This approach is fast as it studies protein crystallization in situ and provides an opportunity to examine many different samples under a range of conditions

From Hurwitz numbers to Kontsevich-Witten tau-function: a connection by Virasoro operators

In this letter,we present our conjecture on the connection between the Kontsevich--Witten and the Hurwitz tau-functions. The conjectural formula connects these two tau-functions by means of the $GL(\infty)$ group element. An important feature of this group element is its simplicity: this is a group element of the Virasoro subalgebra of $gl(\infty)$. If proved, this conjecture would allow to derive the Virasoro constraints for the Hurwitz tau-function, which remain unknown in spite of existence of several matrix model representations, as well as to give an integrable operator description of the Kontsevich--Witten tau-function.Comment: 13 page

Метод проектування систем "розумного" будинку з використанням архітектурного шаблону Redux

Article presents the method for designing of smart home systems using the Redux architectural template. The method is based on the adaptation of the Redux architectural template usually used in designing of visual interfaces for use in the Internet of Things sphere. The system of smart home for control of lighting devices with the help of motion and lighting sensors in the rooms of office building was constructed, based on the developed method. The developed design method allows increasing the system reliability and performance. Improved reliability is achieved by reducing the number of direct relationships between system components. The developed design method also helps reduce the amount of information that is duplicated in different components of the system by using one common data store to save the state, which increases the speed of updating the state of the system and the speed of lighting appliances settings changing. The benefits of using the developed design method are experimentally demonstrated by emulating the work of the smart home system, with saving and analysis of lighting settings change time, before and after the usage of Redux pattern. The design method for smart home systems using the Redux architectural pattern allows scaling system by adding new sensors and appliances to the developed system without losing the speed of data processing and transmission of control commands to the devices. The example presented in this paper show the advantage of developed method usage for designing of smart home systems, that will provide the functionality of appliances automated control in large residential, administrative and office buildings with a large number of simultaneously occurring events that are detected by system for further processing and require appropriate changes to the state of the smart home system settings.Розроблено метод проектування систем "розумного" будинку з використанням архітектурного шаблону Redux. Метод ґрунтується на адаптації архітектурного шаблону Redux, що застосовується для проектування візуальних інтерфейсів до використання у сфері Інтернету речей. На підставі розробленого методу побудовано систему "розумного" будинку для управління освітлювальними приладами за допомогою давачів руху та освітлення у приміщеннях офісної будівлі. Розроблений метод проектування дає змогу підвищити показники надійності та швидкодії роботи системи. Покращення надійності досягається завдяки зниженню кількості прямих взаємозв'язків між компонентами системи. Також розроблений метод проектування сприяє зниженню обсягу інформації, яка дублюється у різних компонентах проектованої системи, завдяки використанню одного загального сховища даних для збереження стану, за рахунок чого підвищується швидкість оновлення станів системи та швидкість зміни налаштувань освітлювальних приладів. Переваги використання методу проектування експериментально відображено за допомогою емуляції роботи системи, "розумного" будинку з подальшим збереженням та аналізом показників швидкості зміни налаштувань освітлювальних приладів – до застосування та після застосування архітектурного шаблону Redux. Запропонований метод дає змогу масштабувати систему додаючи нові давачі та побутові прилади до розробленої системи без втрати швидкості опрацювання даних та передачі команд керування приладами. Розглянутий у роботі приклад надає перевагу запровадженню методу для проектування систем "розумного" будинку, що застосовуватимуться у сфері масового обслуговування, надаючи функціональність автоматизованого керування приладами у великих житлових, адміністративних і офісних будівлях з загальною характерною рисою великої кількості одночасно виникаючих подій, які надходять до системи для подальшого опрацювання та потребують відповідних змін станів налаштувань системи "розумного" будинку

BGWM as Second Constituent of Complex Matrix Model

Earlier we explained that partition functions of various matrix models can be constructed from that of the cubic Kontsevich model, which, therefore, becomes a basic elementary building block in "M-theory" of matrix models. However, the less topical complex matrix model appeared to be an exception: its decomposition involved not only the Kontsevich tau-function but also another constituent, which we now identify as the Brezin-Gross-Witten (BGW) partition function. The BGW tau-function can be represented either as a generating function of all unitary-matrix integrals or as a Kontsevich-Penner model with potential 1/X (instead of X^3 in the cubic Kontsevich model).Comment: 42 page

Glucocorticoids Rapidly Activate cAMP Production via G\u3csub\u3eαs\u3c/sub\u3e to Initiate Non-Genomic Signaling That Contributes to One-Third of Their Canonical Genomic Effects

Glucocorticoids are widely used for the suppression of inflammation, but evidence is growing that they can have rapid, non-genomic actions that have been unappreciated. Diverse cell signaling effects have been reported for glucocorticoids, leading us to hypothesize that glucocorticoids alone can swiftly increase the 3′,5′-cyclic adenosine monophosphate (cAMP) production. We found that prednisone, fluticasone, budesonide, and progesterone each increased cAMP levels within 3 minutes without phosphodiesterase inhibitors by measuring real-time cAMP dynamics using the cAMP difference detector in situ assay in a variety of immortalized cell lines and primary human airway smooth muscle (HASM) cells. A membrane- impermeable glucocorticoid showed similarly rapid stimulation of cAMP, implying that responses are initiated at the cell surface. siRNA knockdown of Gαs virtually eliminated glucocorticoidstimulated cAMP responses, suggesting that these drugs activate the cAMP production via a G protein-coupled receptor. Estradiol had small effects on cAMP levels but G protein estrogen receptor antagonists had little effect on responses to any of the glucocorticoids tested. The genomic and non-genomic actions of budesonide were analyzed by RNA-Seq analysis of 24 hours treated HASM, with and without knockdown of Gαs. A 140-gene budesonide signature was identified, of which 48 genes represent a non-genomic signature that requires Gαs signaling. Collectively, this non-genomic cAMP signaling modality contributes to one-third of the gene expression changes induced by glucocorticoid treatment and shifts the view of how this important class of drugs exerts its effect