2,4-Dibromo-2,3-dihydro-1H-inden-1-yl acetate

In the title compound, C11H10Br2O2, the cyclo­pentene ring fused to the benzene ring adopts an envelope conformation, with the C atom attached to the Br atom as the flap. The crystal structure does not exhibit any classical hydrogen bonds. The mol­ecular packing is stabilized by van der Waals forces and π–π stacking inter­actions with a centroid–centroid distance of 3.811 (4) Å

Çocuğun gelişiminde bağlanma, ilgi-bakım ve aile dinamiklerinin etkisi

TÜBİTAK SBB01.02.200

2-(4-Bromophenyl)-4-(4-methoxyphenyl)- 6,7,8,9-tetrahydro-5H-cyclohepta[ b] pyridine

In the title compound, C23H22BrNO, the cycloheptane ring adopts a chair conformation. The pyridine ring makes dihedral angles of 58.63 (15) and 8.27 (16)degrees with the benzene rings. The dihedral angle between the benzene rings is 56.68 (17)degrees. The crystal packing features C - Br center dot center dot center dot pi interactions [Br center dot center dot center dot centroid distances= 3.813 (2) and 3.839 (2) angstrom; C - Br center dot center dot center dot centroid = 126.25 (10) and 138.31 (10)degrees, respectively, forming a three dimensional supramolecular architecture

2-(4-Bromophenyl)-4-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine

In the title compound, C23H22BrNO, the cycloheptane ring adopts a chair conformation. The pyridine ring makes dihedral angles of 58.63 (15) and 8.27 (16)° with the benzene rings. The dihedral angle between the benzene rings is 56.68 (17)°. The crystal packing features C—Br...π interactions [Br...centroid distances= 3.813 (2) and 3.839 (2) Å; C—Br...centroid = 126.25 (10) and 138.31 (10)°, respectively, forming a three dimensional supramolecular architecture

Rzadka przyczyna przepukliny pachwinowej: torbiel więzadła obłego

Torbiel mezotelialna więzadła obłego to rzadka przyczyna przepukliny pachwinowej. Zwykle jest rozpoznawana podczas zabiegów operacyjnych, które podejmowane są ze względu z wstępną diagnozę przepukliny pachwinowej. W badaniu staramy się przedstawić przypadki dwóch pacjentek, które lekarzom naszej kliniki zgłosiły występowanie zgrubienia w okolicy pachwinowej, i u których za pomocą ultrasonografii, obrazów rezonansu magnetycznego i obrazów tych pozyskanych w trakcie zabiegu, zdiagnozowano torbiel więzadła obłego

Kulak küpesi takılan buzağılarda akut dönemde oksidatif stres değişimler

This study aimed to investigate the effects of ear-tagging on blood malondialdehyde (MDA), reduced glutathione (rGSH), Vitamin C (Vit C) levels, and glutathione peroxidase (GPx) activity in the acute period. Ear-tagged (with polyurethane ear-tag) animals consisted of nine healthy Holstein calves (2-3 months old). Blood samples were taken just before ear-tagging (baseline), at the 20th min, on the 3rd day, and 8th day after the ear-tagging procedure. Six Holstein calves were involved the sham group. In ear-tagged animals, plasma MDA levels increased on the 3rd day compared to baseline values (p<0.01) and returned to baseline values on the 8th day, whereas no change was found in the sham group. In ear-tagged animals, plasma rGSH levels increased at the 20th min, 3rd day, and 8th day (p<0.001) in comparison to baseline values, which in the sham group, there was no change. In ear-tagged animals, erythrocyte rGSH levels on the 3rd and 8th days were higher compared to baseline and 20th min level (p<0.01). In the sham group, the 3rd and 8th day erythrocyte rGSH levels increased compared to baseline values (p<0.01). In ear-tagged animals, the 20th min, 3rd day, and 8th day erythrocyte GPx activities were lower than the baseline values (p<0.001), whereas in the sham group, no change was observed. While Vit C levels increased progressively in the sham group (p<0.05), this increase was not observed in the ear-tagged group. In conclusion, ear-tagging was found to cause oxidative stress and increase antioxidant requirement in calves.Bu çalışmanın amacı kulak küpelemenin akut dönemde kan malondialdehid (MDA), redükte glutatyon (rGSH), vitamin C (Vit C) düzeyleri ile glutatyon peroksidaz (GPx) aktivitesi üzerine etkilerinin araştırılmasıdır. Çalışmanın deney grubunu, kulak küpeleme (poliüretan kulak küpesi ile) yapılan dokuz adet buzağı (2-3 aylık yaşta) oluşturdu. Kan örnekleri kulak küpeleme işleminden hemen önce (temel seviye), kulak küpeleme sonrası 20. dakika, 3. gün ve 8. gün’de alındı. Ayrıca, belirtilen zamanlarda sadece kanları alınan altı adet Holstein ırkı buzağı da sham grubu olarak kullanıldı. Kulak küpeli buzağılarda 3. gün MDA seviyeleri temel seviyelere göre yükselirken (p<0,01), 8. günde tekrar temel seviyelerine indi. Sham grubunda ise MDA düzeyleri yönünden bir değişiklik gözlenmedi. Kulak küpeleme grubunda plazma rGSH seviyeleri 20. dakika, 3. gün ve 8. günde temel düzeylere göre arttı (p<0.001); ancak, sham gurubunda bir değişim gözlenmedi. Kulak küpeli buzağılarda eritrosit rGSH seviyeleri 3. ve 8. günlerde, 20. dakika ve temel seviyelere göre yüksek olarak belirlendi (p<0.01). Sham grubunda ise 3. ve 8. gün eritrosit rGSH seviyeleri temel seviyelere nazaran yüksek olarak belirlendi (p<0.01). Kulak küpeleme grubunda eritrosit GPx aktiviteleri 20. dakika, 3. gün ve 8. gün’lerde temel seviyelere kıyasla düşük (p<0.001) olmasına rağmen, sham grubunda bir değişim göstermedi. Sham grubunda Vit C seviyeleri giderek artmasına rağmen (p<0.05), kulak küpeli hayvanlarda bu artış görülmedi. Sonuç olarak kulak küpelemenin buzağılarda oksidatif strese neden olarak antioksidan ihtiyacı arttırdığı düşünüldü

Computer-guided technique evaluation of the bony palate for planning individual implant placement

WOS: 000402126000006PubMed ID: 27783198Objective Different clinical problems may require a surgical approach to the dental arch, such as dentofacial orthopedics, implant-supported dental prothesis, maxillary orthodontics protraction, removable appliances, and post-traumatic dental reconstruction. The aim of this study is to analyze the dental arch size and type for supporting individual dental protheses. Materials and methods In this study, the reference measurements on the length of the bony palate, maxillary intercanine width, maxillary intermolar width, and the ratio of the maxillary to the palatinal surface were studied in 120 bony palates using a computer software program. Results The average length of the bony palate, maxilla, and palatine was measured as 104.4 +/- 30.3, 40.05 +/- 4.05, and 15.00 +/- 3.03 mm, respectively. The right and left sides of average width of intermaxillary distances were measured as 13.75 +/- 1.50 and 12.51 +/- 1.50 mm, respectively. The average width of intermolar distance was calculated as 19.82 +/- 1.61 mm (right side) and 18.89 +/- 1.69 mm (left side), respectively. The maxillary dentitions were classified as square (17%), round-square (63.5%), round (14.4%), and round V-shaped arches (5.1%). The round-square ones showed no prominent principal component. Among the maxillary arches, the round arches were characterized by small values and round V-shaped ones with the largest values. Asymmetry between the right and the left bony palate was observed. The areas with equal bony palate on both sides were present in 64.4% of the cases, and in 33.1% of the cases, bony palate was dominant on the right. Conclusions The primary principle in reconstructive treatment should be describing geometrical forms and mathematical details of the bony palate. Three-dimensional reference values relative to the dental arch may increase the success of individual treatment of surgical procedures and reduce possible complications. With the help of certain software, this research has made possible to investigate the variability of the dental arch and calculate the variety in measurements and thereby determining the most appropriate implant position, optimizing the implant axis and defining the best surgical and prosthetic solution for the patient

Computerized analysis of the greater palatine foramen to gain the palatine neurovascular bundle during palatal surgery

WOS: 000394975100008PubMed ID: 27177906Investigation of the computerized dimensional anatomic location of the greater palatine foramen (GPF) and lesser palatine foramens (LPF) is important indicating site to collect palatal donor tissue, reconstructioning the orofacial area of the oncology patient and applying the greater palatine nerve block anesthesia. The aim of this study is to determine a patient-friendly landmark and to specify the precise location of the GPF in order to standardise certain anatomical marks of safe neurovascular bundle. 120 bony palates were examined to detect the position of the GPF and the LPF related to adjacent anatomical landmarks using a computer software program. The GPF was assessed regarding the position, the diameter and the distances between each foramen and the midline maxillary suture (MMS), the inner border of alveolar ridge (AR), posterior palatal border (PBB), and incisive foramen (IF). The GPF was identified as single in 81 %, double in 16 %, triple in 2 % and absent in 2 % of the specimens. The mean distances between the GPF and the MSS, the GPF and the AR, the GPF and the PPB, the GPF and the IF were 16, 4, 4, and 40 mm, respectively. In majority of the cases, the GPF was seen between the distal surfaces of the third maxillary molar (78 %). Single LPF was observed in 53.45 % of the skulls, two LPF were observed in 31 % of the skulls bilaterally and five LPF were rare in 2.1 % of the specimens. The LPF was most commonly at the junction of the palatine bone and the inner lamella of the pterygoid plate (71.9 %). This study made possible to investigate the variability of the GPF and the feasibility of the greater palatine neurovascular bundle, and to calculate the lengths of some parameters with the help of certain software. To collect the donor tissue of the neurovascular greater palatine network, each distance among the AR-GPF-PPB were equal to 4 mm. To estimate the possible length of the graft, the incision was made along the third and the second molar to the IF as 4 cm. The data we obtained within this study have been presented to help the surgeons avoid unexpected hemorrhage during the palatinal procedures such as posttraumatic dental reconstruction, maxillofacial tumor resections, palatal micro-implants, and dentofacial orthopedic surgery

Three-dimensional evaluation of the danger zone of ethmoidal foramens on the frontoethmoidal suture line on the medial orbital wall

celik, servet/0000-0002-1102-4417WOS: 000361640400006PubMed: 25613792It is clear that the importance of the ethmoidal foramen (EF) is based on its vascular contents. The frontoethmoidal suture (FS) line is recommended as more reliable navigational landmark for identifying the EF. The vertical orientation between the EF and the FS line was studied in 188 orbits using a computer software program. 146 anterior EFs (77.7 %) and 42 anterior EFs (22.3 %) were situated in the FS line as intrasutural and extrasutural, respectively. 146 posterior EFs (77.25 %) and 8 posterior EFs (4.25 %) were presented as intrasutural and extrasutural, respectively. Although accessory EFs were detected in 25.5 % specimen exhibited an extrasutural location. Majority of the EFs (1-4 EFs) were situated on the FS line. The mean distances from the FS and the anterior EF, the posterior EF and the accessory EF were measured as 2.1 +/- A 0.5, 2.0 +/- A 1.5 and 2.3 +/- A 1.2 mm, respectively. The range of the distances from the FS to the anterior EF, posterior EF and accessory EF were -1.2 to 3.32 , -1.02 to 5.76 and -1.1 to 3.65 mm, respectively. The ranges of EF changed within 1-6 mm. As the FS is not a single point, it is more suitable to make the incision 7 mm above the suture line. The data from this study to help the orbital surgeons explain and avoid unexpected hemorrhage during the orbital procedures such as posttraumatic orbital reconstruction, orbital tumor resections, anterior skull base reconstruction, and orbital decompression surgery