Role of anatomical sites and correlated risk factors on the survival of orthodontic miniscrew implants:a systematic review and meta-analysis

Abstract Objectives The aim of this review was to systematically evaluate the failure rates of miniscrews related to their specific insertion site and explore the insertion site dependent risk factors contributing to their failure. Search methods An electronic search was conducted in the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Knowledge, Scopus, MEDLINE and PubMed up to October 2017. A comprehensive manual search was also performed. Eligibility criteria Randomised clinical trials and prospective non-randomised studies, reporting a minimum of 20 inserted miniscrews in a specific insertion site and reporting the miniscrews’ failure rate in that insertion site, were included. Data collection and analysis Study selection, data extraction and quality assessment were performed independently by two reviewers. Studies were sub-grouped according to the insertion site, and the failure rates for every individual insertion site were analysed using a random-effects model with corresponding 95% confidence interval. Sensitivity analyses were performed in order to test the robustness of the reported results. Results Overall, 61 studies were included in the quantitative synthesis. Palatal sites had failure rates of 1.3% (95% CI 0.3–6), 4.8% (95% CI 1.6–13.4) and 5.5% (95% CI 2.8–10.7) for the midpalatal, paramedian and parapalatal insertion sites, respectively. The failure rates for the maxillary buccal sites were 9.2% (95% CI 7.4–11.4), 9.7% (95% CI 5.1–17.6) and 16.4% (95% CI 4.9–42.5) for the interradicular miniscrews inserted between maxillary first molars and second premolars and between maxillary canines and lateral incisors, and those inserted in the zygomatic buttress respectively. The failure rates for the mandibular buccal insertion sites were 13.5% (95% CI 7.3–23.6) and 9.9% (95% CI 4.9–19.1) for the interradicular miniscrews inserted between mandibular first molars and second premolars and between mandibular canines and first premolars, respectively. The risk of failure increased when the miniscrews contacted the roots, with a risk ratio of 8.7 (95% CI 5.1–14.7). Conclusions Orthodontic miniscrew implants provide acceptable success rates that vary among the explored insertion sites. Very low to low quality of evidence suggests that miniscrews inserted in midpalatal locations have a failure rate of 1.3% and those inserted in the zygomatic buttress have a failure rate of 16.4%. Moderate quality of evidence indicates that root contact significantly contributes to the failure of interradicular miniscrews placed between the first molars and second premolars. Results should be interpreted with caution due to methodological drawbacks in some of the included studies

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Purpose: To evaluate the content of trace elements in Galium incanum SM. subsp. centrale Ehrend. Methods: The air-dried aerial parts of the plant material were used and its water extract (2 % w/v infusion) was analysed for trace elements using x-ray fluorescence (XRF) spectrometry. Results: The aqueous extract depicted significant concentrations of macro-and micro-nutrients with heavy metal and metal oxide content of 4.07 - 6.02 and 3.19 - 4.01 % for powdered plant material and water extract, respectively. The contents of Ca (22840 ppm) and K (8204 ppm) were the highest among all the elements while Zn (45.9 ppm) and Fe (328 ppm) were also detected in significant amounts. Zn, Mn and Cu showed the highest content while those of Mg, Al, K, Ca, Fe and P lowest in the water extract. Conclusion: The presence of significant levels of Ca, K, Na, Fe, Zn, Mg, Mn and Cu in G. incanum subsp. centrale showed that this plant has notable nutrient elements. The traditional use of Gallium species as a diuretic may be attributed to its rich content of potassium

ASIAN JOURNAL OF CHEMISTRY

Centaurea calolepis Boiss., Centaurea lydia Boiss. and Centaurea polyclada DC. were investigated for major minerals and trace elements by X-ray fluorescence spectrometry. Calcium and potassium were found in maximum concentrations in Centaurea species. The results revealed that the concentrations of iron, manganese and zinc were found to be high in C. calolepis. On the other hand, copper, magnesium and phosphorous were found in higher concentrations in C. polyclada. Mineral composition of Centaurea species, will be descriptive in terms of the traditional use of this species. In addition, C. calolepis, C. lydia and C. polyclada may be utilized in nutraceuticals as potential natural sources of major minerals and trace elements

Quantitative determination of ?-tocopherol and quality control studies in Sarcopoterium spinosum L [Sarcopoterium spinosum L. Üzerinde ?-Tokoferol Miktar Tayini ve Kalite Kontrol Çali{dotless}şmalari{dotless}]

A quantitative determination of ?-tocopherol in Sarcopoterium spinosum L. extracts was carried out by TLC-densitometry and HPLC-UV method. The ?-tocopherol content in S. spinosum was established between 0.017210-0.023744 % (TLC-densitometry) and 0.025966-0.037212 % (HPLC-UV). The highest amount of ?-tocopherol was obtained from aerial parts in fruiting period in both methods. In addition, contents of humidity, total ash and sulphated ash of plant samples were determined according to DAB 10

A comparative evaluation of chlorogenic acid content and antioxidant activity in artichoke (cynara scolymus L.) samples under different storage conditions

2-s2.0-85099370887Artichoke has been used for a long time in the traditional medicine against dyspeptic complaints and as a liver protector due to its choleretic and cholagogue effects. Chlorogenic acid, the main ingredient of artichoke is known to show hepatoprotector, anticancer, anti-obesity and antioxidant activities. In this study, antioxidant activity and chlorogenic acid quantification were performed using the samples of artichoke as fresh, boiled, frozen, boiled frozen, canned, fresh leaf and dry leaf. Potential antioxidant activity was evaluated using DPPH assay. Flavonoid and phenolic contents were determined by Aluminum chloride colorimetry and Folin-Ciocalteu methods. The amounts of colorogenic acid in the samples were determined by HPLC-DAD system. The results have shown that highest chlorogenic acid content was determined in the 10-minute frozen-boiled sample (0.01441 mg/100g), followed by canned (0.01043 mg/100g), 20-minute cooked artichoke (0.001912 mg/100g), fresh artichoke (0.001519 mg/100g) and frozen artichoke (0.0004 mg/100g). The antioxidant activity results have revealed that highest % DPPH capture effect was observed in the cooked artichoke sample (ED50 =1.949 mg/ml). The total flavonoid content was equivalent to quercetin (43.859 mg QE/100g) whereas total phenolic content equalled to gallic acid (14.640 mg GAE/100g). The antioxidant activity and the amounts of colorogenic acid were found to be the highest in the cooked artichoke sample whereas the lowest antioxidant activity observed in canned artichoke. The results show that the heat treatment applied for storage can positively affect the amount of chlorogenic acid and antioxidant activity. © 2020 Chemical Society of Pakistan. All rights reserved

Antioxidant activity of the mycelium of 21 wild mushroom species

In this study, the antioxidant activity of mycelia from 21 wild mushrooms - Agaricus bresadolanus, Auricularia auriculajudae, Chroogomphus rutilus, Fomes fomentarius, Ganoderma lucidum, Gloeophyllum trabeum, Gymnopus dryophilus, Infundibulicybe geotropa, Inocybe flocculosa var. crocifolia, Inocybe catalaunica, Lentinula edodes, Lentinus sajor-caju, Lycoperdon excipuliforme, Macrolepiota excoriata, Morchella esculenta var. rigida, Morchella intermedia, Omphalotus olearius, Pleurotus djamor, Postia stiptica, Rhizopogon roseolus and Stropharia inuncta - were investigated. Antioxidant properties of ethanol, chloroform and water extracts of these 21 mycelia were studied by two methods: free radical scavenging (DPPH) and the scavenging activity of 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonic acid) radical cation (ABTS.+). Among the 21 mushroom extracts, Omphalotus olearius displayed the most potent antioxidant activity. The study has shown that these wild macrofungi have potential as natural antioxidants. © 2010 Mycological Society of China.TBAG-107T668The authors wish to express their profound gratitude to the Scientific and Technological Research Council of Turkey (TUBITAK, Accessing code number: TBAG-107T668) for financial support. -

Investigating the effects of Hericium erinaceus extracts on telomerase activity in MCF-7 cells

41st FEBS Congress on Molecular and Systems Biology for a Better Life -- SEP 03-08, 2016 -- Kusadasi, TURKEYWOS: 000383616901075FEB