Evolving temporal fuzzy association rules from quantitative data with a multi-objective evolutionary algorithm

A novel method for mining association rules that are both quantitative and temporal using a multi-objective evolutionary algorithm is presented. This method successfully identifies numerous temporal association rules that occur more frequently in areas of a dataset with specific quantitative values represented with fuzzy sets. The novelty of this research lies in exploring the composition of quantitative and temporal fuzzy association rules and the approach of using a hybridisation of a multi-objective evolutionary algorithm with fuzzy sets. Results show the ability of a multi-objective evolutionary algorithm (NSGA-II) to evolve multiple target itemsets that have been augmented into synthetic datasets

QCD Phase Transition with Strange Quark in Wilson Formalism for Fermions

The nature of QCD phase transition is studied with massless up and down quarks and a light strange quark, using the Wilson formalism for quarks on a lattice with the temporal direction extension $N_t=4$. We find that the phase transition is first order in the cases of both about 150 MeV and 400 MeV for the strange quark mass. These results together with those for three degenerate quarks suggest that QCD phase transition in nature is first order.Comment: uuencoded compressed tar file, LaTeX, 13 pages, 9 figures, Minor errors for quoting references are corrected and a reference is adde

Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing.

Recent efforts to comprehensively characterize great ape genetic diversity using short-read sequencing and single-nucleotide variants have led to important discoveries related to selection within species, demographic history, and lineage-specific traits. Structural variants (SVs), including deletions and inversions, comprise a larger proportion of genetic differences between and within species, making them an important yet understudied source of trait divergence. Here, we used a combination of long-read and -range sequencing approaches to characterize the structural variant landscape of two additional Pan troglodytes verus individuals, one of whom carries 13% admixture from Pan troglodytes troglodytes. We performed optical mapping of both individuals followed by nanopore sequencing of one individual. Filtering for larger variants (>10 kbp) and combined with genotyping of SVs using short-read data from the Great Ape Genome Project, we identified 425 deletions and 59 inversions, of which 88 and 36, respectively, were novel. Compared with gene expression in humans, we found a significant enrichment of chimpanzee genes with differential expression in lymphoblastoid cell lines and induced pluripotent stem cells, both within deletions and near inversion breakpoints. We examined chromatin-conformation maps from human and chimpanzee using these same cell types and observed alterations in genomic interactions at SV breakpoints. Finally, we focused on 56 genes impacted by SVs in >90% of chimpanzees and absent in humans and gorillas, which may contribute to chimpanzee-specific features. Sequencing a greater set of individuals from diverse subspecies will be critical to establish the complete landscape of genetic variation in chimpanzees

Comparison of Exact and perturbative Results for Two Metrics

We compare the exact and perturbative results in two metrics and show that the spurious effects due to the perturbation method do not survive for physically relevant quantities such as the vacuum expectation value of the stress-energy tensor.Comment: 12 page

Order-by-disorder in the antiferromagnetic Ising model on an elastic triangular lattice

Geometrically frustrated materials have a ground-state degeneracy that may be lifted by subtle effects, such as higher order interactions causing small energetic preferences for ordered structures. Alternatively, ordering may result from entropic differences between configurations in an effect termed order-by-disorder. Motivated by recent experiments in a frustrated colloidal system in which ordering is suspected to result from entropy, we consider in this paper, the antiferromagnetic Ising model on a deformable triangular lattice. We calculate the displacements exactly at the microscopic level, and contrary to previous studies, find a partially disordered ground state of randomly zigzagging stripes. Each such configuration is deformed differently and thus has a unique phonon spectrum with distinct entropy, thus lifting the degeneracy at finite temperature. Nonetheless, due to the free-energy barriers between the ground-state configurations, the system falls into a disordered glassy state.Comment: Accepted to PNA

Triple-negative breast carcinomas of low malignant potential: review on diagnostic criteria and differential diagnoses

Triple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and prognostic parameters of breast neoplasms of special histotypes. Specifically, adenoid cystic carcinoma, adenomyoepithelioma, acinic cell carcinoma, mucoepidermoid carcinoma, tall cell carcinoma with reverse polarity, and secretory carcinoma will be discussed. For each tumour, definition and morphological and molecular features, together with prognostic parameters, will be presented. Paradigmatic cases will be illustrated

Finite Temperature Transitions in Lattice QCD with Wilson Quarks --- Chiral Transitions and the Influence of the Strange Quark ---

The nature of finite temperature transitions in lattice QCD with Wilson quarks is studied near the chiral limit for the cases of 2, 3, and 6 flavors of degenerate quarks ($N_F=2$, 3, and 6) and also for the case of massless up and down quarks and a light strange quark ($N_F=2+1$). Our simulations mainly performed on lattices with the temporal direction extension $N_t=4$ indicate that the finite temperature transition in the chiral limit (chiral transition) is continuous for $N_F=2$, while it is of first order for $N_F=3$ and 6. We find that the transition is of first order for the case of massless up and down quarks and the physical strange quark where we obtain a value of $m_\phi/m_\rho$ consistent with the physical value. We also discuss the phase structure at zero temperature as well as that at finite temperatures.Comment: uuencoded compressed tar file, 70 pages, 32 figure