ヨウジ ヲ タイショウ ト シタ カンキョウ キョウイク プログラム ノ ココロミ ―トウキョウ ノウギョウ ダイガク イセハラ ノウジョウ ヲ ジレイ ト シテー

本研究では，東京農業大学農学分野の教員・技術員と幼稚園教諭とが連携し，野菜や果樹栽培の教育研究を活かした環境教育プログラムを試みた。本研究では，プログラムのねらいに応じて伊勢原農場内で教育素材を選定し，環境教育プログラムを実施した。環境教育プログラムでは，ステビア，レモングラス，コキアを五感で体験し植物の用途や効用を学ぶ環境教育プログラムを実施した。加えて，幼児が日常生活で親しんでいる野菜・果樹としてブトウ，ブルーベリー，ミニトマトの栽培技術や品種の違いを学ぶ環境教育プログラムを実施した。本プログラムの教育効果として，伊勢原農場の多様な果樹・野菜とその栽培技術は幼児たちに身近な野菜や果樹への発見，楽しさ，感動を与え，観察した物事を記録できる観察力や理解力の向上を確認できた。In this research, faculty members and technical engineers from Tokyo University of Agriculture have conducted a trial environmental education program in cooperation with the teachers of the Seijo Kindergarten utilizing vegetable and fruit cultivation related educational research. Specifically, the objectives besides holding the actual educational event was to clarify the purpose of the educational program and to select the education materials for future use. As part of the environmental education program, children learned about the uses and effects of the plants Sevia, Lemongrass and Bassia Scoparia using their five senses. In addition, children were able to learn about the different cultivation methods and varieties of everyday vegetables and fruits that they encounter on a daily basis such as grapes, blueberries and cherry tomatoes. As a result of the program children were evidently able to improve their observation skills and comprehension skills by taking notes of their new discoveries, joys and impressions of everyday vegetables, while they learned about the wide varieties of vegetables and fruits of the Isehara Farmland and their cultivation methods. Meanwhile, as for the provision of the Isehara Farmland as a sustainable venue of environmental education, the establishment of an acceptance system and the securing of human resources remain as potential issues

Development and Practice of Introductory Teaching Materials for Science "Problem- Based Learning" on the Theme of "Removal of Roadside Utility Poles"

P(論文)平成29年～ 30年に改訂された学習指導要領においては，持続可能な開発のための教育（ESD）や主権者教育などが取り上げられている．本稿では，新・逆向き設計に基づき，SDGsに関連した政策の評価を「総合的な学習の時間」で生徒が取り組めるようにするため，各教科で行う探究活動の準備段階で用いるゲーミング教材について，特に理科の物理と生物の知識を活用する教材を開発した．教材は無電柱化の政策に関する評価を題材とし，学習した知識と関連付ける形で優先的に無電柱化に取り組む地域の優先度を検証する活動を通じて，探究活動の流れと探究における知識活用の方法論を学び今後取り組む探究活動や市民生活における理科の知識の活用の見通しを得ることを教材の目標とした．実践の結果，生徒は理科の知識の重要性を認識した一方，教材に関しては化学の知識活用の追加，時間配分の改善，定量的評価を用いた探究の導入の3 点の改善点があった．departmental bulletin pape

Predictors and preventers of postoperative bedridden status in the elderly ages over 75 after emergency general surgery: a retrospective cohort study

Aim We investigated the proportion of bedridden patients after emergency surgery among the elderly ages over 75; defined as the latter‐stage elderly in Japan, the associated factors, and interventions used to prevent it. Methods Eighty‐two latter‐stage elderly patients who underwent emergency surgery for non‐traumatic illness between January 2020 and June 2021 in our hospital were included in the study. Backgrounds and various perioperative factors were compared retrospectively between the groups including patients who became bedridden from Performance Status Scale 0 to 3 before admission (Bedridden group) and those who did not (Keep group). Results Three cases of death and seven patients who were bedridden before admission were excluded. The 72 remaining patients were divided into the Bedridden group (n = 10, 13.9%) and the Keep group (n = 62, 86.1%). There were significant differences in the prevalence of dementia, pre‐ and postoperative circulatory dynamics, renal dysfunction, coagulation abnormality, length of stay in the high care unit/intensive care unit, and number of hospital days, with a relative risk of 13 (1.74–96.71), a sensitivity of 1.00, and a specificity of 0.67 for a preoperative shock index of 0.7 or higher being associated with the Bedridden group. Among patients with a preoperative shock index of 0.7 or higher, there was a significant difference in SI at 24 h postoperatively between the two groups. Conclusion Preoperative shock index may be the most sensitive predictor. Early circulatory stabilization seems to be protective against patients becoming bedridden

Whole-Genome Sequence of Fluoroquinolone-Resistant Escherichia coli HUE1, Isolated in Hokkaido, Japan

We report the complete genome sequence of Escherichia coli strain HUE1, isolated from the urinary catheter of a female patient, showing fluoroquinolone resistance without quinolone resistance-determining region mutations. To facilitate the exploration of the molecular characteristics of HUE1, the whole genome was sequenced using long- and short-read platforms

Probucol attenuates hyperoxia-induced lung injury in mice

<div><p>Hyperoxic lung injury is pathologically characterized by alveolar edema, interlobular septal edema, hyaline membrane disease, lung inflammation, and alveolar hemorrhage. Although the precise mechanism by which hyperoxia causes lung injury is not well defined, oxidative stress, epithelial cell death, and proinflammatory cytokines are thought to be involved. Probucol—a commercially available drug for treating hypercholesterolemia—has been suggested to have antioxidant and antiapoptotic effects. This study aimed to assess whether probucol could attenuate hyperoxic lung injury in mice. Mice were exposed to 95% O₂ for 72 h, with or without pre-treatment with 130 μg/kg probucol intratracheally. Probucol treatment significantly decreased both the number of inflammatory cells in the bronchoalveolar lavage fluid and the degree of lung injury in hyperoxia-exposed mice. Probucol treatment reduced the number of cells positive for 8-hydroxyl-2′-deoxyguanosine or terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and suppressed NF-κB activation, Bax expression, and caspase-9 activation in lung tissues from hyperoxia-exposed mice. These results suggest that probucol can reduce oxidative DNA damage, apoptotic cell death, and inflammation in lung tissues. Intratracheal administration of probucol may be a novel treatment for lung diseases induced by oxidative stress, such as hyperoxic lung injury and acute respiratory distress syndrome.</p></div