The communications system in the USSR

"May 1977.""2136"--handwritten on coverIncludes bibliographical references (p. 71-72

CA19-9 Normalization During Pre-operative Treatment Predicts Longer Survival for Patients with Locally Progressed Pancreatic Cancer

BACKGROUND: Compared to the widely-adopted 2–4 months of pre-operative therapy for patients with borderline resectable (BR) or locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC), our institution tends to administer a longer duration before considering surgical resection. Using this unique approach, the aim of this study was to determine preoperative variables associated with survival. METHODS: Records from patients with BR/LA PDAC who underwent attempt at surgical resection from 1992–2014 were reviewed. RESULTS: After a median duration of 6 months of pre-operative treatment, 109 patients with BR/LA PDAC (BR 63, LA 46) were explored; 93 (85.3%) underwent pancreatectomy. Those who received at least 6 months of pre-operative treatment had longer median overall survival (OS) than those who received less (52.8 vs. 32.1 months, P=0.044). On multivariate analysis, pre-operative treatment duration was the strongest predictor of survival (hazard ratio (HR) 4.79, P=0.043). However, OS was similar in those whose CA19-9 normalized regardless of whether they received more or less than 6 months of chemotherapy (71.4 vs. 101.8 months, P=0.930). CONCLUSIONS: Pre-operative CA19-9 decline can guide treatment duration in patients with BR/LA PDAC. We endorse 6 months of therapy except in those patients whose values normalize, where surgery can be considered after a shorter course

Archaelogy and history of eighth-century Judah

Resumen: Ensayos de un grupo internacional de expertos sobre el antiguo Cercano Oriente y la Biblia hebrea que honran el trabajo pionero de Oded Borowski en la arqueología y la historia del antiguo Israel y Judá. Los colaboradores abordan la cuestión de lo que sabemos del Judá del siglo VIII desde múltiples ángulos, incluyendo un estudio de los vecinos de Judá, la tierra de Judá y sus ciudades, la vida diaria y la cultura material, las creencias y prácticas religiosas, y las primeras formas de lo que ahora son los textos bíblicos. Entre los colaboradores se encuentran Rami Arav, Shawn Zelig Aster, Assaf Avraham, Jeffrey A. Blakely, Sandra Blakely, Elizabeth Bloch-Smith, Efrat Bocher, Erin Darby, Jennie Ebeling, Zev I. Farber, Avraham Faust, Daniel E. Fleming, Yuval Gadot, Kristine Garroway, Seymour Gitin, James W. Hardin, Gilad Itach, Hayah Katz, Reinhard G. Kratz, Joel M. LeMon, Shani Libi, Oded Lipschits, Donald Redford, Christopher Rollston, Bruce Routledge, Yair Sapir, Konrad Schmid, Cynthia Shafer-Elliott, Brent A. Strawn, Andy Vaughn, Jacob L. Wright, y K. Lawson Younger Jr. Características: - Énfasis en la influencia de Asiria en las culturas políticas, religiosas y materiales de Judá; Múltiples modelos para las primeras etapas de la escritura y composición bíblica; Información actualizada sobre tipologías de cerámica