How do potential users perceive the adoption of new technologies within the field of Artificial Intelligence and Internet-of-Things? - A revision of the UTAUT 2 model using Voice Assistants

The following study investigates the perception potential users have when considering the adoption of voice assistants (VAs). VAs are considered to possess characteristics linkable to both, Artificial Intelligence (AI) and the Internet-of-Things (IoT). This thesis aims to provide a deeper understanding of the determinants influencing the adoption of the new VA technology using the Unified Theory of Acceptance and Use of Technology 2 model (UTAUT 2), a theoretical model explaining technology adoption and usage behaviour. The amount of gadgets being released to the market which possess characteristics of the AI and IoT technology increases constantly, while the 2012 version of the UTAUT 2 model was not constructed for these. In a qualitative approach conducting four focus groups, the aim of this study is to find out about the perceptions of potential future users on the VA technology and as a consequence amend the current UTAUT 2 model to fit newly upcoming technologies which possess similar characteristics as VAs within the AI and IoT field. The study found out that while hedonic motivation seems to be of inferior relevance, the determinants data security, compatibility and relationship with the device are essential influencing factors to take into consideration when trying to fully understand users’ technology adoption perceptions. However, the fact that these technologies are still in the early stage of adoption make it difficult for future users, to fully judge their own adoption behaviour if they are no members of the early innovation adoption curve stages. For further research, it is recommended to look into different sampling groups and apply the model resulting from this study to new upcoming technologies within the area of AI and IoT

Surgeon-performed sonographic findings in a traumatic trans-anal rectal perforation

Early diagnosis and active management of trans-anal rectal injuries is essential for a favorable outcome. Intraperitoneal free air (IFA) is usually diagnosed by an erect Chest X-ray. Point-of-care ultrasound has been recently used to detect IFA. We report a 45-year-old male who presented to the Emergency Department with lower abdominal peritonitis. Surgeon-performed portable point-of-care ultrasound as an extension of the abdominal examination revealed an inflamed omentum with hypoechoic stranding, thickened non compressible small bowel, and free fluid in the pelvis. A transverse abdominal section of the right upper quadrant showed free intraperitoneal air. Rectal examination revealed a longitudinal rectal tear. Laparotomy has confirmed the sonographic findings. There was a 12 cm intraperitoneal tear of the anterior wall of the rectum which was necrotic. This case clearly demonstrates that portable point-of-care ultrasound gives very useful detailed information even when performed by a non radiologist. Surgeons should be encouraged to use point-of-care ultrasound after appropriate training

Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?

Background: Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown. Methods: Case report and literature review. Results: We present preterm twins whose mother was treated with venlafaxine, a nonselective serotonin reuptake inhibitor, throughout pregnancy until delivery. The twins developed neonatal necrotizing enterocolitis. Conclusion: The question whether there might be a correlation between maternal serotonin reuptake inhibitor therapy and neonatal necrotizing enterocolitis is discusse

Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?

Background: Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown. Methods: Case report and literature review. Results: We present preterm twins whose mother was treated with venlafaxine, a nonselective serotonin reuptake inhibitor, throughout pregnancy until delivery. The twins developed neonatal necrotizing enterocolitis. Conclusion: The question whether there might be a correlation between maternal serotonin reuptake inhibitor therapy and neonatal necrotizing enterocolitis is discusse

Steckbrief «DOCA – Database of Variables for Content Analysis». Zur Relevanz, Zielstellung, Inhalt und Partizipationsmöglichkeiten der Datenbank für Operationalisierungen der standardisierten Inhaltsanalyse

Die Open Access Database of Variables for Content Analysis DOCA sammelt, systematisiert und evaluiert Operationalisierungen für die standardisierte manuelle und automatisierte Inhaltsanalyse in der Kommunikationswissenschaft. DOCA soll Forschenden das Finden von geeigneten und etablierten bzw. getesteten Operationalisierungen (sowie den gesamten Codebüchern) für die standardisierte Inhaltsanalyse erleichtern. Für die kommunikationswissenschaftliche Forschung soll dies mit einer besseren Vergleichbarkeit inhaltsanalytischer Studien und Projekte sowie einer erhöhten Bedeutungszuschreibung der Transparenz von Operationalisierungen und Qualitätsindikatoren einhergehen. Mit dem vorliegenden Steckbrief sind zwei zentrale Zielsetzungen verbunden: Erstens soll über DOCA und deren Einsatzgebiete informiert werden und so auch der Bekanntheitsgrad dieser Forschungsinfrastruktur gesteigert werden. Zweitens soll dieser Artikel aus der Perspektive der Herausgeberinnen den Prozess und die damit verbundenen Herausforderungen für die Konzeption, Realisation und Aufrechterhaltung einer Forschungsinfrastruktur darlegen. The Open Access Database of Variables for Content Analysis (DOCA) collects, systematizes, and evaluates operationalizations for standardized manual and automatic content analysis in the field of communication science. DOCA aims to facilitate researchers in finding suitable and established or tested operationalizations (as well as complete codebooks) for standardized content analysis. For communication science research, this is expected to result in increased comparability of content analytic studies and projects, as well as greater emphasis on the transparency of operationalizations and quality indicators. The present fact sheet is associated with two central objectives: firstly, to provide information about DOCA and its applications, thereby increasing awareness of this research infrastructure. Secondly, from the personal perspective of the editors, this article aims to outline the process and associated challenges involved in the conception, realization, and maintenance of a research database

Dietary Silicon Deficiency Does Not Exacerbate Diet-Induced Fatty Lesions in Female ApoE Knockout Mice.

BACKGROUND: Dietary silicon has been positively linked with vascular health and protection against atherosclerotic plaque formation, but the mechanism of action is unclear. OBJECTIVES: We investigated the effect of dietary silicon on 1) serum and aorta silicon concentrations, 2) the development of aortic lesions and serum lipid concentrations, and 3) the structural and biomechanic properties of the aorta. METHODS: Two studies, of the same design, were conducted to address the above objectives. Female mice, lacking the apolipoprotein E (apoE) gene, and therefore susceptible to atherosclerosis, were separated into 3 groups of 10-15 mice, each exposed to a high-fat diet (21% wt milk fat and 1.5% wt cholesterol) but with differing concentrations of dietary silicon, namely: silicon-deprived (-Si; <3-μg silicon/g feed), silicon-replete in feed (+Si-feed; 100-μg silicon/g feed), and silicon-replete in drinking water (+Si-water; 115-μg silicon/mL) for 15-19 wk. Silicon supplementation was in the form of sodium metasilicate (feed) or monomethylsilanetriol (drinking water). RESULTS: The serum silicon concentration in the -Si group was significantly lower than in the +Si-feed (by up to 78%; P < 0.003) and the +Si-water (by up to 84%; P < 0.006) groups. The aorta silicon concentration was also lower in the -Si group than in the +Si-feed group (by 65%; P = 0.025), but not compared with the +Si-water group. There were no differences in serum and aorta silicon concentrations between the silicon-replete groups. Body weights, tissue wet weights at necropsy, and structural, biomechanic, and morphologic properties of the aorta were not affected by dietary silicon; nor were the development of fatty lesions and serum lipid concentrations. CONCLUSIONS: These findings suggest that dietary silicon has no effect on atherosclerosis development and vascular health in the apoE mouse model of diet-induced atherosclerosis, contrary to the reported findings in the cholesterol-fed rabbit model

a randomized controlled trial

Diurnal carbohydrate and fat distribution modulates glycaemic control in rodents. In humans, the optimal timing of both macronutrients and its effects on glycaemic control after prolonged consumption are not studied in detail. In this cross-over trial, 29 non-obese men were randomized to two four-week diets: (1) carbohydrate-rich meals until 13.30 and fat-rich meals between 16.30 and 22.00 (HC/HF) versus (2) inverse sequence of meals (HF/HC). After each trial period two meal tolerance tests were performed, at 09.00 and 15.40, respectively, according to the previous intervention. On the HF/HC diet, whole-day glucose level was increased by 7.9% (p = 0.026) in subjects with impaired fasting glucose and/or impaired glucose tolerance (IFG/IGT, n = 11), and GLP-1 by 10.2% (p = 0.041) in normal glucose-tolerant subjects (NGT, n = 18). Diet effects on fasting GLP-1 (p = 0.009) and PYY (p = 0.034) levels were observed in IFG/IGT, but not in NGT. Afternoon decline of glucose tolerance was more pronounced in IFG/IGT and associated with a stronger decrease of postprandial GLP-1 and PYY levels, but not with changes of cortisol rhythm. In conclusion, the HF/HC diet shows an unfavourable effect on glycaemic control in IFG/IGT, but not in NGT subjects. Consequently, large, carbohydrate-rich dinners should be avoided, primarily by subjects with impaired glucose metabolism

Manuelle standardisierte Inhaltsanalyse

Die manuelle Inhaltsanalyse gilt nach wie vor als zentrale Methode kommunikationswissenschaftlicher Forschung. Die nachfolgenden Ausführungen sollen ein Grundverständnis über Merkmale, Schritte, Qualitätskriterien und Schwerpunkte der manuellen Inhaltsanalyse vermitteln, die für die Nachvollziehbarkeit von Konzept und Idee des Handbuchs behilflich sein können. So wird in diesem Kapitel deutlich, was unter standardisierter Inhaltsanalyse – auch in Abgrenzung zur qualitativen Inhaltsanalyse – verstanden wird. Zudem werden auch Qualitätskriterien der manuellen Inhaltsanalyse skizziert, die bei der Auswahl der berichteten Studien in diesem Handbuch und auch der Operationalisierungen für die dazugehörige Datenbank zentral waren

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Sepsis remains a persistent problem on intensive care units all over the world. Understanding the complex mechanisms of sepsis is the precondition for establishing new therapeutic approaches in this field. Therefore, animal models are required that are able to closely mimic the human disease and also sufficiently deal with scientific questions. The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. In this model, a small stent is surgically inserted into the ascending colon of mice or rats leading to a continuous leakage of intestinal bacteria into the peritoneal cavity. The procedure results in peritonitis, systemic bacteraemia, organ infection by gut bacteria, and systemic but also local release of several pro- and anti-inflammatory cytokines. The lethality of CASP can be controlled by the diameter of the inserted stent. A variant of this model, the so-called CASP with intervention (CASPI), raises opportunity to remove the septic focus by a second operation according to common procedures in clinical practice. CASP is an easily learnable and highly reproducible model that closely mimics the clinical course of abdominal sepsis. It leads way to study on questions in several scientific fields e.g. immunology, infectiology, or surgery