The Incidence of Debris Disks at 24 {\mu}m and 670 Myr

We use Spitzer Space Telescope 24 {\mu}m data to search for debris disks among 122 AFGKM stars from the \sim 670 Myr clusters Hyades, Coma Ber, and Praesepe, utilizing a number of advances in data reduction and determining the intrinsic colors of main sequence stars. For our sample, the 1{\sigma} dispersion about the main sequence V-K, K-[24] locus is approximately 3.1%. We identify seven debris disks at 10% or more (\geq 3{\sigma} confidence level) above the expected K-[24] for purely photospheric emission. The incidence of excesses of 10% or greater in our sample at this age is 5.7 +3.1/-1.7%. Combining with results from the literature, the rate is 7.8 +4.2/-2.1% for early- type (B9 - F4) stars and 2.7 +3.3/-1.7% for solar-like (F5 - K9) stars. Our primary sample has strict criteria for inclusion to allow comparison with other work; when we relax these criteria, three additional debris disks are detected. They are all around stars of solar-like type and hence reinforce our conclusion that disks around such stars are still relatively common at 670 Myr and are similar to the rate around early-type stars. The apparently small difference in decay rates between early-type and solar-like stars is inconsistent with the first order theoretical predictions that the later type stellar disks would decay an order of magnitude more quickly than the earlier type ones.Comment: 26 pages, 3 figures, accepted for publication in Ap

Division I Female Cross-Country Runners’ Perception of Eating Behaviors and Attitudes Toward Health: A Pilot Study

International Journal of Exercise Science 11(3): 941-956, 2018.The complexity behind nutritional decisions and the impact of these decisions on overall health (both physical and emotional) in the Division I female runner is not yet well understood. Thus, the purpose of this study was to explore the perspectives of female collegiate cross-country runners from a Division I school on eating behaviors and attitudes toward health. In this qualitative study, six NCAA Division I female collegiate cross-country runners participated in individual interviews. Through qualitative analysis, three themes (Nutritional Views, Identity as a Runner, and Psychological Factors) and 11 subthemes emerged. The interactions that occurred between the subthemes and themes demonstrated that there were multiple interacting factors influencing the athletes’ nutritional behaviors. Intrinsic factors consisted of maintaining self-control, perception of trust and available time. Extrinsic factors included availability of a nutritionist, family and team support, and availability of nutritious food. These findings give some insight into the nutritional decisions in female runners, but it is a complex issue. It is evident that individualized education regarding eating behavior is needed for the female athlete

Designing Traditions: Student Explorations in the Asian Textile Collection

Exhibition Notes, Number 32,Summer 2008. RISD’s newest generation of textile designers source the RISD Museum’s vast Asian textile collection in this popular collaborative project and biennial exhibition. Traditional craftsmanship sparks contemporary creativity as objects inspire innovative new textiles and garments.https://digitalcommons.risd.edu/risdmuseum_journals/1016/thumbnail.jp

Association of a Communication Training Program With Use of Antipsychotics in Nursing Homes

Importance: Off-label antipsychotic prescribing in nursing homes (NHs) is common and is associated with increased risk of mortality in older adults. Prior large-scale, controlled trials in the NH setting failed to show meaningful reductions in antipsychotic use. Objective: To quantify the influence of a large-scale communication training program on NH antipsychotic use called OASIS. Design, Setting, and Participants: This investigation was a quasi-experimental longitudinal study of NHs in Massachusetts enrolled in the OASIS intervention. Participants were residents living in NHs between March 1, 2011, and August 31, 2013. The data were analyzed from December 2015, to March 2016, and from November through December 2016. Exposures: The OASIS educational program targets all NH staff (direct care and nondirect care) using a train-the-trainer model. The program goals were to reframe challenging behaviors of residents with cognitive impairment as the communication of unmet needs, to train staff to anticipate resident needs, and to integrate resident strengths into daily care plans. Main Outcomes and Measures: This study used an interrupted time series model of facility-level prevalence of antipsychotic medication use, other psychotropic medication use (antidepressants, anxiolytics, and hypnotics), and behavioral disturbances to evaluate the intervention\u27s effectiveness in participating facilities compared with control NHs in Massachusetts and New York. The 18-month preintervention (baseline) period was compared with a 3-month training period, a 6-month implementation period, and a 3-month maintenance period. Results: This study included 93 NHs enrolled in the OASIS intervention (27 of which had a high prevalence of antipsychotic use) compared with 831 nonintervention NHs. Among OASIS facilities, prevalences of atypical antipsychotic prescribing were 34.1% at baseline and 26.5% at the study end (absolute reduction of 7.6% and relative reduction of 22.3%) compared with a drop of 22.7% to 18.8% in the comparison facilities (absolute reduction of 3.9% and relative reduction of 17.2%). In the OASIS implementation phase, NHs experienced a reduction in antipsychotic use prevalence among OASIS facilities (-1.20%; 95% CI, -1.85% to -0.09% per quarter) greater than that among non-OASIS facilities (-0.23%; 95% CI, -0.47% to 0.01% per quarter), resulting in a net OASIS influence of -0.97% (95% CI, -1.85% to -0.09%; P = .03). A difference in trend was not sustained in the maintenance phase (difference of 0.93%; 95% CI, -0.66% to 2.54%; P = .48). No increases in other psychotropic medication use or behavioral disturbances were observed. Conclusions and Relevance: Antipsychotic use prevalence declined during OASIS implementation of the intervention, but the decreases did not continue in the maintenance phase. Other psychotropic medication use and behavioral disturbances did not increase. This study adds evidence for nonpharmacological programs to treat behavioral and psychological symptoms of dementia

“I don’t have any emotions”: An ethnography of emotional labour and feeling rules in the emergency department

Aims: This study aims to apply Hochschild's theory of emotional labour to emergency care, and uncover the 'specialty-specific' feeling rules driving this labour. Despite the importance of positive nurse wellbeing, the emotional labour of nursing (a great influencer in wellbeing) remains neglected. Design and Methods: Ethnography enabled immersion in the ED setting, gathering the lived experiences and narratives of the ED nursing team. We undertook first-hand observations at one major trauma center ED and one district general ED including semi-structured interviews (18). A reflexive and interpretive approach towards thematic analysis was utilised. Results: We unearthed and conceptulaised four feeling rules born from this context and offer extensive insights into the emotional labour of emergency nurses. Conclusion: Understanding the emotional labour and feeling rules of various nursing specialties offers critical insight into the challenges facing staff-fundamental for nursing wellbeing and associated retention programs. Impact: What problem did the study address? A lack of (theoretical and empirical) knowledge relating to emotional labour, and associated feeling rules, in the ED. What were the main findings? The distinctive context has significant implications for the emotional labour undertaken. This labour was driven by four, enculturated feeling rules which we conceptualised. Where and on whom will the research have impact? Academically, this research expands our understanding-we know little of nurses' feeling rules and how specialties influence them. Clinically, (including service managers and policy makers) there are practical implications for nurse wellbeing

Investigation of eight candidate genes on chromosome 1p36 for autosomal dominant total congenital cataract

Purpose: To identify the causative gene for autosomal dominant total congenital cataract in a six-generation Australian family displaying linkage to chromosome 1p36. Methods: Eight candidate genes (HSPB7, FBXO42, EFHD2, ZBTB17, CAPZB, FBLIM1, ALDH4A1, and MFAP2) from within the previously defined linkage interval were selected based on expression in lens and their known or putative function. The coding exons were sequenced in multiple affected family members and compared to the reference sequence. Results: No segregating mutations were identified in any of the eight genes. Thirty-one polymorphisms were detected, 20 of which were in the exons and 11 in the flanking introns. Conclusions: Coding mutations in HSPB7, FBXO42, EFHD2, ZBTB17, CAPZB, FBLIM1, ALDH4A1, and MFAP2 do not account for congenital cataract in this family

Severe mental illness and chronic kidney disease: a cross-sectional study in the United Kingdom.

OBJECTIVE: We investigated the burden of chronic kidney disease (CKD) among patients with severe mental illness (SMI). METHODS: We identified patients with SMI among all those aged 25-74 registered in the UK Clinical Practice Research Datalink as on March 31, 2014. We compared the prevalence of CKD (two measurements of estimated glomerular filtration rate <60 mL/min/1.73 m2 for ≥3 months) and renal replacement therapy between patients with and without SMI. For patients with and without a history of lithium prescription separately, we used logistic regression to examine the association between SMI and CKD, adjusting for demographics, lifestyle characteristics, and known CKD risk factors. RESULTS: The CKD prevalence was 14.6% among patients with SMI and a history of lithium prescription (n = 4,295), 3.3% among patients with SMI and no history of lithium prescription (n = 24,101), and 2.1% among patients without SMI (n = 2,387,988; P < 0.001). The prevalence of renal replacement therapy was 0.23%, 0.15%, and 0.11%, respectively (P = 0.012). Compared to patients without SMI, the fully adjusted odds ratio for CKD was 6.49 (95% CI 5.84-7.21) for patients with SMI and a history of lithium prescription and 1.45 (95% CI 1.34-1.58) for patients with SMI and no history of lithium prescription. The higher prevalence of CKD in patients with SMI may, in part, be explained by more frequent blood testing as compared to the general population. CONCLUSION: CKD is identified more commonly among patients with SMI than in the general population

New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors

The permeability of large cations through the P2X pore has remained arguably the most controversial and complicated topic in P2X-related research, with the emergence of conflicting studies on the existence, mechanism and physiological relevance of a so-called “dilated” state. Due to the important role of several “dilating” P2X subtypes in numerous diseases, a clear and detailed understanding of this phenomenon represents a research priority. Recent advances, however, have challenged the existence of a progressive, ATP-induced pore dilation, by demonstrating that this phenomenon is an artifact of the method employed. Here, we discuss briefly the history of this controversial and enigmatic dilated state, from its initial discovery to its recent reconsideration. We will discuss the literature in which mechanistic pathways to a large cation-permeable state are proposed, as well as important advances in the methodology employed to study this elusive state. Considering recent literature, we will also open the discussion as to whether an intrinsically dilating P2X pore exists, as well as the physiological relevance of such a large cation-permeable pore and its potential use as therapeutic pathway