8 research outputs found

    Aspects cliniques et thérapeutiques des anomalies de la jonction pyélo-urétérale au CHU du point G

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    Cette Ă©tude a Ă©tĂ© faite pour analyser les aspects cliniques et thĂ©rapeutiques des anomalies de la jonction pyĂ©lo-urĂ©tĂ©rale. Etude transversale et descriptive portant sur 35 cas d'anomalies de la jonction pyĂ©lo-urĂ©tĂ©rale (AJPU) colligĂ©s au service d'Urologie du CHU du Point G durant une pĂ©riode de 4 ans (Janvier 2010 au DĂ©cembre 2014). Les donnĂ©es ont Ă©tĂ© recueillies sur les fiches d'enquĂȘte, les dossiers mĂ©dicaux et les registres du bloc. Les donnĂ©es sociodĂ©mographique, clinique et thĂ©rapeutique ont Ă©tĂ© saisies sur Microsoft Word 2007 et analysĂ©es sur Excel 2007 et SPSS 18.0. 35 cas d'AJPU ont Ă©tĂ© colligĂ©s en 4 ans. La moyenne d'Ăąge Ă©tait de 29,3 ans. La douleur lombaire Ă©tait le motif de consultation le plus frĂ©quent soit 40 %. 20 % des patients ont Ă©tĂ© en consultation pour la premiĂšre fois 10 ans d'Ă©volution symptomatique. Une destruction rĂ©nale avait Ă©tĂ© observĂ©e dans 28,6 %. Le couple Echographie + UIV a permis d'Ă©tablir le diagnostic chez 37,1 %. La complication lithiasique Ă©tait prĂ©sente chez 17,1 % des patients. 51,4 % des patients ont reçu une pyĂ©loplastie Ă  ciel ouvert selon Anderson KUSS. L'anomalie de la jonction pyĂ©lo-urĂ©tĂ©rale dans notre Ă©tude a Ă©tĂ© caractĂ©risĂ©e par un retard de consultation avec des complications redoutables. La chirurgie Ă  ciel ouvert a Ă©tĂ© le gold standard avec des rĂ©sultats satisfaisants. L'endopyĂ©loplastie, la cure de la jonction coelioscopique sont des chirurgies mini invasives non disponible chez nous mais Ă  encourager et Ă  intĂ©grer dans l'arsenal thĂ©rapeutique.Pan African Medical Journal 2016; 2

    Kyste géant para-urétral feminine

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    Le kyste gĂ©ant para-urĂ©tral fĂ©minin infectĂ© est rarement rapportĂ© dans la littĂ©rature. Ce kyste est diffĂ©rent du diverticule sous urĂ©tral sur le plan clinique, diagnostique et thĂ©rapeutique. Sa pathogĂ©nie se confond avec celle  des diverticules sous urĂ©traux. Son traitement n’est pas bien codifiĂ©, vu sa raretĂ©. Nous rapportons un cas atypique de kyste gĂ©ant para urĂ©tral infectĂ© chez une jeune femme de 26 ans. Le kyste Ă©tait  symptomatique et la patiente a eu un traitement chirurgical. Nous discutons les aspects cliniques,  diagnostiques et thĂ©rapeutiques de cette entitĂ© rare Ă  travers une revue de la littĂ©rature.Key words: Kyste gĂ©ant, para urĂ©tral, fĂ©minin, chirurgi

    Etude épidémiologique, clinique et thérapeutique des hydrocÚles dans trois districts sanitaires de la région de Sikasso/Mali: Epidemiological, Clinical and Therapeutic Study of Hydroceles in Three Health Districts in the Sikasso Region / Mali

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    Context and objective. Hydrocele is one of the most common urogenital manifestations of lymphatic filariasis. It is a common cause of enlarged scrotum in the tropics. This study aims to describe the epidemiological, clinical and therapeutic aspects of hydroceles. Methods. This cross-sectional descriptive study of hydroceles in three endemic filarial Sikasso areas in Mali was conducted from November 2017 to December 2018. The variables studied were: frequency of hydrocele, age of patients, duration of evolution, type of anesthesia, surgical technique, volume, operative time and postoperative results. Results. Three hundred fifty-eight patients were operated on in fourteen months. The frequency of hydrocele‘s surgery was 31%. Their average age was 47.1 years old (extremes 4 months and 94 years). The duration of evolution was 10.7 years (extremes 6 months and 21 years). The right side was the most affected with 44.1% followed by the left side with 31.3%. Hydrocele was bilateral in 19%. Local anesthesia (with xylocaine 2%) was used in 88%. All patients underwent a successful vaginal resection. Conclusion. The hydrocele remains a common urological pathology in these endemic areas. The diagnosis is made after a long period of evolution of the disease. Treatment in outpatient surgery is undertaken using local anesthesia. These hydrocele management campaigns should be encouraged to treat the maximum number of patients. Contexte et objectif. L’hydrocĂšle constitue l’une des manifestations urogĂ©nitales les plus frĂ©quentes de la filariose lymphatique. Elle est une cause frĂ©quente de grosse bourse dans les rĂ©gions tropicales. L’objectif de cette Ă©tude est de dĂ©crire les aspects Ă©pidĂ©miologiques, cliniques et thĂ©rapeutiques des hydrocĂšles. MĂ©thodes. Il s’agissait d’une Ă©tude transversale et descriptive sur les hydrocĂšles, rĂ©alisĂ©e entre novembre 2017 et dĂ©cembre 2018 ; dans trois zones endĂ©miques filariennes dans la rĂ©gion de SIKASSO au Mali. Les variables Ă©tudiĂ©es Ă©taient : la frĂ©quence de l’hydrocĂšle, l’ñge des patients, la durĂ©e d’évolution, le type d’anesthĂ©sie, la technique chirurgicale, le volume, le temps opĂ©ratoire et les rĂ©sultats postopĂ©ratoires. RĂ©sultats. Trois cent cinquante-huit patients ont Ă©tĂ© opĂ©rĂ©s en quatorze mois. L’intervention de l’hydrocĂšle rendait compte de 31% des activitĂ©s chirurgicales. Leur Ăąge moyen Ă©tait de 47,1 ans (extrĂȘmes 4 mois et 94 ans). La durĂ©e d’évolution Ă©tait de 10,7 ans (extrĂȘmes de 6 mois et 21 ans). Le testicule droit Ă©tait le plus touchĂ© (44,1 %) suivi du cĂŽtĂ© gauche (31,3%). L’hydrocĂšle Ă©tait bilatĂ©rale dans 19 %. L’anesthĂ©sie locale Ă  la xylocaĂŻne 2 % a Ă©tĂ© rĂ©alisĂ©e dans 88%. La rĂ©section vaginale a Ă©tĂ© rĂ©alisĂ©e chez tous les patients avec succĂšs. Conclusion. L’hydrocĂšle reste une pathologie urologique frĂ©quente en zone d’endĂ©mie filarienne. Le diagnostic se fait aprĂšs une longue durĂ©e d’évolution de la maladie. Le traitement en chirurgie ambulatoire rĂ©alisĂ©e sous anesthĂ©sie locale a montrĂ© des rĂ©sultats satisfaisants. Ces campagnes de prise en charge de l’hydrocĂšle sont Ă  encourager pour pouvoir traiter le maximum de patients

    First Molecular Characterization of Chronic Hepatitis B Carriers in Timbuktu, Mali

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    In Mali, hepatocellular carcinoma (HCC) is the third and sixth most common cancer in men and women, respectively. Mali comprises several distinct climato-ecological zones. Most studies to date have been conducted in the sub-Sahelian zone of southern Mali, including the capital city Bamako. In this part of the country, the main risk factors for HCC are chronic hepatitis B virus (HBV) carriage and dietary exposure to aflatoxins, a well-known hepatocarcinogen. Data are scarce for other ecological zones, but our preliminary data from 721 blood donors in the area of Timbuktu, presented in this study, suggest that chronic HBV carriage is also endemic in the northern Saharan zone of Mali. For further study, 29 healthy HBV chronic carrier volunteers were recruited from the blood transfusion center in Timbuktu. Successful viral genotyping in 20 volunteers revealed HBV genotype E in 13 cases and D in 7 cases, suggesting that this geographical and anthropological transition zone may also represent a transition zone between HBV genotypes that dominate sub-Saharan and northern Africa, respectively. Sequencing of circulating cell-free plasma DNA (cfDNA) from donors did not reveal the presence of the TP53 R249S mutation in these donors, a marker of dietary exposure to aflatoxins in sub-Saharan Africa. These results suggest that the geo-epidemiological distribution of the risk factors for HCC is not uniform across Mali, but is dependent upon climatic, socioeconomic and anthropological factors that might have an impact on patterns of chronic liver disease and cancer

    First Molecular Characterization of Chronic Hepatitis B Carriers in Timbuktu, Mali

    No full text
    In Mali, hepatocellular carcinoma (HCC) is the third and sixth most common cancer in men and women, respectively. Mali comprises several distinct climato-ecological zones. Most studies to date have been conducted in the sub-Sahelian zone of southern Mali, including the capital city Bamako. In this part of the country, the main risk factors for HCC are chronic hepatitis B virus (HBV) carriage and dietary exposure to aflatoxins, a well-known hepatocarcinogen. Data are scarce for other ecological zones, but our preliminary data from 721 blood donors in the area of Timbuktu, presented in this study, suggest that chronic HBV carriage is also endemic in the northern Saharan zone of Mali. For further study, 29 healthy HBV chronic carrier volunteers were recruited from the blood transfusion center in Timbuktu. Successful viral genotyping in 20 volunteers revealed HBV genotype E in 13 cases and D in 7 cases, suggesting that this geographical and anthropological transition zone may also represent a transition zone between HBV genotypes that dominate sub-Saharan and northern Africa, respectively. Sequencing of circulating cell-free plasma DNA (cfDNA) from donors did not reveal the presence of the TP53 R249S mutation in these donors, a marker of dietary exposure to aflatoxins in sub-Saharan Africa. These results suggest that the geo-epidemiological distribution of the risk factors for HCC is not uniform across Mali, but is dependent upon climatic, socioeconomic and anthropological factors that might have an impact on patterns of chronic liver disease and cancer
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