Biopsychosocial implications of living with multiple sclerosis: a qualitative study using interpretative phenomenological analysis

Background: Multiple sclerosis (MS) is estimated to affect 2.8 million people worldwide, with increasing prevalence in all world regions (Walton et al). While there is no cure for MS, medication and lifestyle modifications can slow disease progression and enhance patients’ quality of life. The biopsychosocial model of health recognises important interactions among biological, psychological and social factors in illness, including those relating to illness management, which contribute to the experience of those diagnosed with MS. Objective: This qualitative, idiographic study aimed to explore the lived experiences of patients in the United Arab Emirates (UAE) diagnosed with S. Methods: Semistructured interviews were conducted with a purposive sample of eight patients with MS ranging in age from 25 to 56 years. All participants were residing in the UAE at the time of data collection. Interpretative phenomenological analysis was used to analyse the data. Results: Three superordinate themes were identified from patients’ candid accounts of their lives with MS, highlighting issues of illness management, acceptance and gratitude, and adaptive coping. These themes broadly illustrate biological, psychological and social aspects of patients’ MS experiences. Conclusion: The study emphasised the importance of adopting the biopsychosocial model to treat and manage MS. Additionally, it highlights the need for routine assessment and early, multidimensional approach with multidisciplinary team efforts to improve patients’ quality of life

Eliciting preferences for attributes of Newcastle disease vaccination programmes for village poultry in Ethiopia

Newcastle disease (NCD) is an important disease of poultry, directly affecting the livelihoods of poor farmers across developing countries. Research has identified promising innovations in NCD vaccine development and field trials among village poultry have been promising. However, NCD vaccination is not currently part of village poultry extension programmes in many developing countries. Understanding the preferences for, and relative importance of, different attributes of potential vaccination programmes to prevent NCD will be crucial in designing acceptable and sustainable prevention programmes. This research employed the discrete choice experiment approach to elicit farmers’ preference for attributes of NCD vaccination programmes for village poultry in rural Ethiopia. The choice experiment survey was conducted on 450 smallholder farmers. The relative importance of attributes of NCD vaccines to farmers was estimated using a random parameter logit regression model. The preferred NCD vaccine programme had greater bird-level protection (i.e. greater capacity to reduce mortality should NCD occur in a flock), was delivered by animal health development agents, and could be administered via drinking water. Results from simulations on changes in attribute levels revealed that bird-level protection capacity and delivery of vaccine by animal heath extension affect farmers’ preferences more than other attributes. These findings suggest that it is important to ensure NCD vaccine programmes offer reasonable capacity to protect against mortality. It also suggests the need to understand farmers’ preferred vaccine delivery mechanisms and route of vaccine administration for a wider acceptance of vaccine

Crossing the Rift valley: using complete mitogenomes to infer the diversification and biogeographic history of ethiopian highlands Ptychadena (anura: Ptychadenidae)

The Ethiopian Highlands are considered a biodiversity hotspot, harboring a high number of endemic species. Some of the endemic species probably diversified in situ; this is, for example, the case of a monophyletic clade containing 12 known species of grass frogs of the genus Ptychadena. The different species occur at elevations ranging from 1,500 to above 3,400 m and constitute excellent models to study the process of diversification in the highlands as well as adaptations to high elevations. In this study, we sampled 294 specimens across the distribution of this clade and used complete mitogenomes and genome-wide SNP data to better understand how landscape features influenced the population structure and dispersal of these grass frogs across time and space. Using phylogenetic inference, population structure analyses, and biogeographic reconstructions, we found that the species complex probably first diversified on the south-east side of the Great Rift Valley. Later on, species dispersed to the north-west side, where more recent diversification occurred. We further demonstrate that Ptychadena species have dispersed across the Great Rift Valley at different times. Our analyses allowed for a more complete understanding of the contribution of geological events, biogeographic barriers and climatic changes as drivers of species diversification and adaptation in this important biogeographic region

Poverty Reduction Effects of Agricultural Technology Adoption: A Micro-evidence from Rural Tanzania

This article evaluates the impact of adoption of improved pigeonpea technologies on consumption expenditure and poverty status using cross-sectional data of 613 households from rural Tanzania. Using multiple econometric techniques, we found that adopting improved pigeonpea significantly increases consumption expenditure and reduces poverty. This confirms the potential role of technology adoption in improving household welfare as higher incomes translate into lower poverty. This study supports broader investment in agriculture research to address vital development challenges. Reaching the poor with better technologies however requires policy support for improving extension efforts, access to seeds and market outlets that stimulate adoption

Economic impacts of fall armyworm and its management strategies: evidence from southern Ethiopia

Published online: 10 Jan 2020This paper explores the economic implications of fall armyworm (FAW) and its management strategies by exploiting exogenous variation in FAW exposure amongst households in southern Ethiopia. We find that FAW exposure affects maize yield and sales negatively, but not consumption. Furthermore, we find evidence of crowding-in and intensification of insecticide use in response to FAW exposure. We also find suggestive evidence that existing extension service arrangements lack the capacity to deal with emerging threats such as FAW. Results imply that targeted interventions aimed at improving the effectiveness of control measures and institutional capacity would be key to reduce the adverse effects of FAW

Correlates of Complete Childhood Vaccination in East African Countries.

Despite the benefits of childhood vaccinations, vaccination rates in low-income countries (LICs) vary widely. Increasing coverage of vaccines to 90% in the poorest countries over the next 10 years has been estimated to prevent 426 million cases of illness and avert nearly 6.4 million childhood deaths worldwide. Consequently, we sought to provide a comprehensive examination of contemporary vaccination patterns in East Africa and to identify common and country-specific barriers to complete childhood vaccination. Using data from the Demographic and Health Surveys (DHS) for Burundi, Ethiopia, Kenya, Rwanda, Tanzania, and Uganda, we looked at the prevalence of complete vaccination for polio, measles, Bacillus Calmette-Guérin (BCG) and DTwPHibHep (DTP) as recommended by the WHO among children ages 12 to 23 months. We conducted multivariable logistic regression within each country to estimate associations between complete vaccination status and health care access and sociodemographic variables using backwards stepwise regression. Vaccination varied significantly by country. In all countries, the majority of children received at least one dose of a WHO recommended vaccine; however, in Ethiopia, Tanzania, and Uganda less than 50% of children received a complete schedule of recommended vaccines. Being delivered in a public or private institution compared with being delivered at home was associated with increased odds of complete vaccination status. Sociodemographic covariates were not consistently associated with complete vaccination status across countries. Although no consistent set of predictors accounted for complete vaccination status, we observed differences based on region and the location of delivery. These differences point to the need to examine the historical, political, and economic context of each country in order to maximize vaccination coverage. Vaccination against these childhood diseases is a critical step towards reaching the Millennium Development Goal of reducing under-five mortality by two-thirds by 2015 and thus should be a global priority

Integrated health interventions for improved livelihoods: a case study in Ethiopia

Open Access Journal; Published online: 14 Mar 2020Smallholder farmers in sub-Saharan Africa (SSA) face multifaceted and co-existing risks, such as human and animal diseases and pests. Even though smallholder farmers often experience these challenges simultaneously, interventions to address these challenges are often implemented in a piecemeal fashion. However, managing agricultural production constraints without alleviating human and livestock health burdens might not generate significant and sustained benefits to achieve the desired development outcome (e.g., reducing hunger, malnutrition, and poverty). As such, building farmers’ resilience and adaptive capacity to co-existing production constraints and health burdens may require an integrated and holistic approach. Understanding the potential benefits of an integrated approach would provide critical information, for example, for revisiting the extension systems and for designing pro-poor holistically integrated interventions to tackle interrelated challenges facing smallholder farmers. In this paper, we examined the economic benefits of integrated human–plant–animal health interventions aimed at controlling malaria, stemborer infestations of crops, and trypanosomiasis, along with beekeeping as a livelihood diversification option in rural Ethiopia. We developed a whole-farm multiperiod mathematical linear programming model to examine the economic consequences of the interventions. Our results suggest that relaxing livelihoods and the human–plant–animal health constraints that farmers face has the potential to at least double income. The results further show that exploiting the potential synergies among interventions can generate higher economic benefits. The annual income from the combined interventions is 35% higher than the sum of the income gains from each intervention alone. Our results support an integrated approach to achieve holistic outcomes in areas where these development constraints co-exist

Determinants of Agricultural Technology adoption: the Case of Improved Pigeonpea Varieties in Tanzania

If dryland legumes are to meet the expectations of reducing poverty and hunger in the semi-arid tropics, there will be need for a full understanding of their potential for diffusion and the barriers to adoption. We apply a program evaluation technique to data obtained from Tanzania to derive estimates of the actual and potential adoption rates of improved pigeonpea varieties and their determinants. The study reveals that only 33% of the sampled farmers were aware of the improved pigeonpea varieties which consequently restricted the sample adoption rate of improved varieties to only 19%. The potential adoption rate of improved pigeonpea if all farmers had been exposed to improved varieties is estimated at 62% and the adoption gap resulting from the incomplete exposure of the population to the improved pigeonpea is 43%. We further find that the awareness of improved varieties is mainly influenced by attendance of Participatory Variety Selection activities. The adoption of improved varieties is more pronounced among farmers with smaller landholdings suggesting that farmers facing land pressure intensify pigeonpea production through the adoption of improved high yielding varieties. The findings are indicative of the relatively large demand for improved pigeonpea varieties suggesting that there is scope for increasing their adoption rate in Tanzania once the farmers are made aware of the existence of the technologies

Estimating the impact of biological control of maize stemborers on productivity and poverty in Kenya: a continuous treatment approach

This study examines the farm-level effects of stemborers’ biological control (BC) using biological and household survey data collected in rural Kenya. The authors use a continuous treatment impact-evaluation method to estimate BC’s average and marginal treatment effects. Findings indicate that, on average, a one percent increase in the intensity of BC increases maize yield by 9.3 kg per hectare and reduces the poverty level of maize-growing farm households by 0.5%. Developing and promoting biological control can be seen as an additional tool in the fight against food insecurity and poverty in Africa through controlling important pests