3,514 research outputs found
Monte Carlo Calculation of Energy Strain on a Muscle Fiber Due to Light Absorption
Monte Carlo models of light propagation in different materials are widely used in today’s science. In this paper the model is applied to a optically non-linear theoretical sample of a muscle fiber to determine the behavior of a photon inside the tissue, the energy absorbed by the sample and matching the energy strain to a possible effect on the fiber
ABC transporter architecture and mechanism: implications from the crystal structures of BtuCD and BtuF
AbstractABC transporters are ubiquitous membrane proteins that facilitate unidirectional substrate translocation across the lipid bilayer. Over the past five years, new crystal structures have advanced our understanding of how ABC transporters couple adenosine triphosphate (ATP) hydrolysis to substrate transport. In the following, we will briefly review the results of these structural investigations and outline their mechanistic implications
Inactivation in vitro of the Escherichia coli outer membrane protein FhuA by a phage T5-encoded lipoprotein
Bacteriophage T5-encoded lipoprotein, synthesized by infected Escherichia coli cells, prevents superinfection of the host cell by this virus. The molecular basis of its ability to inactivate the receptor of phage T5, the FhuA protein, was investigated in vitro. Fully competent T5 lipoprotein, with a His tag attached to the C-terminus, was purified in detergent solution. Co-reconstitution with homogeneous FhuA protein into liposomes revealed that the lipoprotein inhibited the irreversible inactivation of phage T5 by FhuA protein. This phenomenon correlated with the inhibition of phage DNA ejection determined by fluorescence monitoring. Addition of detergent abolished the interaction between T5 lipoprotein and FhuA protein. When the signal sequence and N-terminal cysteinyl residue of the lipoprotein were removed by genetic truncation, the soluble polypeptide could be refolded and purified from inclusion bodies. The truncated lipoprotein interfered with infection of E. coli by phage T5, but only at very high concentrations. Circular dichroism spectra of both forms of T5 lipoprotein exhibited predominantly β-structure. T5 lipoprotein is sufficient for inactivation of the FhuA protein, presumably by inserting the N-terminal acyl chains into the membrane, thus increasing its local concentration. An in vitro stoichiometry of 10:1 has been calculated for the phage-encoded T5 lipoprotein to FhuA protein comple
Empirical study of cartograms
We report on an empirical study investigating the effectiveness and efficiency of spatial inference making with contiguous (value-by-area) cartograms, compared to informational equivalent choropleth maps, combined with graduated circles. We find significant differences in people's inference-making performance dependent on the map type. Overall, results suggest that the choropleth map with graduated circles is more effective and more efficient than the cartogram for the analysis of population census data. However, map effectiveness and efficiency also significantly depends on the inference task complexity, and more surprisingly, on the shape characteristics of the depicted enumeration units. For simple tasks, cartograms seem as effective and efficient as the more traditional mapping method. For complex inference questions, inference performance with cartograms is significantly dependent on whether regular or irregular zones are distorted. As we know still very little about the perception and cognition of cartograms, we hope to shed new light for this intriguing mapping method with this empirical study
Exact ground state of finite Bose-Einstein condensates on a ring
The exact ground state of the many-body Schr\"odinger equation for bosons
on a one-dimensional ring interacting via pairwise -function
interaction is presented for up to fifty particles. The solutions are obtained
by solving Lieb and Liniger's system of coupled transcendental equations for
finite . The ground state energies for repulsive and attractive interaction
are shown to be smoothly connected at the point of zero interaction strength,
implying that the \emph{Bethe-ansatz} can be used also for attractive
interaction for all cases studied. For repulsive interaction the exact energies
are compared to (i) Lieb and Liniger's thermodynamic limit solution and (ii)
the Tonks-Girardeau gas limit. It is found that the energy of the thermodynamic
limit solution can differ substantially from that of the exact solution for
finite when the interaction is weak or when is small. A simple relation
between the Tonks-Girardeau gas limit and the solution for finite interaction
strength is revealed. For attractive interaction we find that the true ground
state energy is given to a good approximation by the energy of the system of
attractive bosons on an infinite line, provided the interaction is stronger
than the critical interaction strength of mean-field theory.Comment: 28 pages, 11 figure
Optimal time-dependent lattice models for nonequilibrium dynamics
Lattice models are abundant in theoretical and condensed-matter physics.
Generally, lattice models contain time-independent hopping and interaction
parameters that are derived from the Wannier functions of the noninteracting
problem. Here, we present a new concept based on time-dependent Wannier
functions and the variational principle that leads to optimal time-dependent
lattice models. As an application, we use the Bose-Hubbard model with
time-dependent Wannier functions to study a quench scenario involving higher
bands. We find a separation of times scales in the dynamics and show that under
some circumstances the multi-band nonequilibrium dynamics of a quantum system
can be obtained essentially at the cost of a single-band model.Comment: 14 pages, 3 figure
Spiders of the UW-Milwaukee Field Station
A checklist of 100 species from 16 families is presented in this preliminary report of spiders at the UWM Field Station. Listed with the species are the months and habitats in which they were collected
The impact of metallic contacts on propagation losses of an underlying photonic crystal waveguide
In view of an electrically pumped photonic crystal-based semiconductor optical amplifier (SOA), we investigate optical mode propagation in 2D PhC waveguides in the presence of metal contacts for carrier injection. Our photonic crystal (PhC) devices are manufactured in the InP/InGaAsP material system. For the loss measurements, we have fabricated contact strips as narrow as 300nm with a sub-50nm placing accuracy on top of W3 waveguides. We study the influence of their position and width on optical power transmission through passive waveguides with respect to viability for future active devices. Our experimental results are complemented by numerical studies (FDTD, plane-wave expansion method)
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