39 research outputs found
IT Systems for Aircraft Weight and Balance at Zagreb International Airport
U prvom djelu rada navedene su uvodne postavke te su definirani potrebni elementi za proces uravnoteženja i optereÄenja zrakoplova. Slijedi opis procesa izrade instrukcije utovara i liste uravnoteženja i optereÄenja zrakoplova. Opisan je naÄin prikupljanja relevantne dokumentacije koja je temelj za izradu liste optereÄenja i uravnoteženja zrakoplova i izrade instrukcije utovara. Rad se fokusira na opisu raÄunalnih aplikacija za uravnoteženje i optereÄenje zrakoplova koje se koriste na MeÄunarodnoj zraÄnoj luci Zagreb na naÄin da se iste prebroje te navede njihov opis i specifiÄnosti. Na kraju rada iznijet je prijedlog poboljÅ”anja postojeÄih operativnih aktivnosti u segmentu raÄunalnog uravnoteženja i optereÄenja zrakoplova.In the first part of the work there are listed introductory settings and defined needed elements for process of weight and balance of the airplane. Ways of making Loading Instruction Report and Load and Trim Sheet of the airplane are descripted. There is described way of collecting relevant documentation which is base for making Loading Instruction Report and load and trim sheet. Work is focused on describing computer applications for weight and balance of the aircraft that are used in Zagreb International Airport, in a way that they are counted and their description and specification are listed. At the end of work there's a stated suggestion of improvements of existing operational activities in segment of computer balance and weight the airplane
Should we still examine our patients?
Mnogi se lijeÄnici danas nekritiÄno oslanjaju na rezultate dijagnostiÄkih pretraga, Å”to rezultira daljnjim nepotrebnim pretragama ili zahvatima. Ovaj rad prikazuje zaÅ”to to nije dobro i kakve su posljedice takve prakse.Many physicians today rely uncritically on the results of diagnostic tests, resulting in further needless examination and interventions. This article shows why this is incorrect and what the consequences of such practices are
IT Systems for Aircraft Weight and Balance at Zagreb International Airport
U prvom djelu rada navedene su uvodne postavke te su definirani potrebni elementi za proces uravnoteženja i optereÄenja zrakoplova. Slijedi opis procesa izrade instrukcije utovara i liste uravnoteženja i optereÄenja zrakoplova. Opisan je naÄin prikupljanja relevantne dokumentacije koja je temelj za izradu liste optereÄenja i uravnoteženja zrakoplova i izrade instrukcije utovara. Rad se fokusira na opisu raÄunalnih aplikacija za uravnoteženje i optereÄenje zrakoplova koje se koriste na MeÄunarodnoj zraÄnoj luci Zagreb na naÄin da se iste prebroje te navede njihov opis i specifiÄnosti. Na kraju rada iznijet je prijedlog poboljÅ”anja postojeÄih operativnih aktivnosti u segmentu raÄunalnog uravnoteženja i optereÄenja zrakoplova.In the first part of the work there are listed introductory settings and defined needed elements for process of weight and balance of the airplane. Ways of making Loading Instruction Report and Load and Trim Sheet of the airplane are descripted. There is described way of collecting relevant documentation which is base for making Loading Instruction Report and load and trim sheet. Work is focused on describing computer applications for weight and balance of the aircraft that are used in Zagreb International Airport, in a way that they are counted and their description and specification are listed. At the end of work there's a stated suggestion of improvements of existing operational activities in segment of computer balance and weight the airplane
IT Systems for Aircraft Weight and Balance at Zagreb International Airport
U prvom djelu rada navedene su uvodne postavke te su definirani potrebni elementi za proces uravnoteženja i optereÄenja zrakoplova. Slijedi opis procesa izrade instrukcije utovara i liste uravnoteženja i optereÄenja zrakoplova. Opisan je naÄin prikupljanja relevantne dokumentacije koja je temelj za izradu liste optereÄenja i uravnoteženja zrakoplova i izrade instrukcije utovara. Rad se fokusira na opisu raÄunalnih aplikacija za uravnoteženje i optereÄenje zrakoplova koje se koriste na MeÄunarodnoj zraÄnoj luci Zagreb na naÄin da se iste prebroje te navede njihov opis i specifiÄnosti. Na kraju rada iznijet je prijedlog poboljÅ”anja postojeÄih operativnih aktivnosti u segmentu raÄunalnog uravnoteženja i optereÄenja zrakoplova.In the first part of the work there are listed introductory settings and defined needed elements for process of weight and balance of the airplane. Ways of making Loading Instruction Report and Load and Trim Sheet of the airplane are descripted. There is described way of collecting relevant documentation which is base for making Loading Instruction Report and load and trim sheet. Work is focused on describing computer applications for weight and balance of the aircraft that are used in Zagreb International Airport, in a way that they are counted and their description and specification are listed. At the end of work there's a stated suggestion of improvements of existing operational activities in segment of computer balance and weight the airplane
The magnitude and clinical implications of the interobserver variability of echocardiographic left ventricular ejection fraction measurement
The ejection fraction (EF) is the most commonly used echocardiographic measure of the systolic left ventricular (LV) function. Echocardiography has however several limitations in measuring LV volumes and EF since the formulas for quantifications are based on geometrical assumptions, the EF parameters (end-systolic and end-diastolic volumes) are preload dependent and adequate projections are not always possible to obtain. Previous studies have also shown correlation between different
echocardiographic techniques of obtaining EF and even correlation between echocardiography and other methods (MRI, SPECT, CT) but the data on interobserver and intraobserver variability remains scarce.1 In this study we examined the interobserver limits of agreement and the therapeutic implications of the uncertainty obtained by the result.
We examined 22 sequential patients referred to our echocardiography
laboratory for LV function assessment. All echocardiography studies were performed by two independent cardiologists blinded to the measurements of the other observer. 2D methods including the biplane Simpson method and āeyeballingā were conducted, while automatic and semiautomatic 2D and 3D methods were not allowed. Bland-Altman analysis was performed to determine the systematic bias and limits of
agreement (LOA) of EF between different observers (Figure 1).
Next the LOA were used to obtain new āconfidence intervalsā on a previously gathered set of echocardiograms of 171 heart failure patients. We recorded the number of patients that now had different treatment recommendations according to the current ESC guidelines on heart failure and device therapy i.e. the ānewā EF was 40%. McNemarās test was used to determine the statistical significance of the difference with a two-tailed P=0.05 taken as a threshold. The bias was calculated to be -2.3 with LOA (7.8 to -12.5) which is in agreement with
similar studies. The number of patients that received ānewā treatment recommendations was 99 for the lower LOA and 65 for upper LOA, P<0.001 for both groups. We therefore conclude that the interobserver variability of the EF measurement can lead to significantly different treatment strategies in patients with heart failure. Echocardiographic
methods introducing less variability (like automatic 3D techniques)
should be preferred in determining the EF
Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men
Aim To determine the association between the number
of thymine-adenine (TA)n dinucleotide repeats in the promoter
region of the gene coding for the estrogen receptor
alpha (ESR1) and the prevalence of lone atrial fibrillation
(AF) in men.
Methods We conducted a case-control study involving 89
men with lone AF and 166 healthy male controls. The ESR1
genotype was established by polymerase chain reaction
and capillary electrophoresis. To assess the association of
ESR1 genotype with AF, logistic regression models were
built with AF as outcome.
Results Men with lone AF had significantly greater
number of (TA)n repeats of single alleles than controls
(mean Ā± standard deviation, 19.2 Ā± 4.2 vs 18 Ā± 4.3, P = 0.010).
After adjustment for other factors, a unit-increase in (TA)n
repeat number was associated with a significantly greater
likelihood of AF (odds ratio 1.069; 95% confidence interval
1.024-1.116, P = 0.002).
Conclusions Our results indicate that a greater number of
(TA)n repeats in the promoter region of ESR1 is associated
with a significantly increased likelihood of lone atrial fibrillation
in men
Staying Focused on Cardiovascular Patients During the COVID-19 Pandemic
Tijekom pandemije COVID-a 19 smanjio se broja pregleda te dijagnostiÄkih i terapijskih zahvata u bolesnika s kardiovaskularnim bolestima. U nekoliko zemalja zabilježen je porast mortaliteta u iste skupine bolesnika, kako od COVID-a 19, tako i od samih kardiovaskularnih bolesti. Važno je nastaviti lijeÄiti takve bolesnike i sprijeÄiti nedostupnost zdravstvene zaÅ”tite zbog subjektivnih ili objektivnih razloga. U tome nam može pomoÄi i telemedicina, no velik dio odgovornosti ostaje na samim bolesnicima da samokontrolom i redovitim uzimanjem terapije sprijeÄe pogorÅ”anje bolesti. Mi im možemo pomoÄi olakÅ”avanjem te zadaÄe (telefonski kontakt, fiksne kombinacije lijekova). TakoÄer je važno zdravstvenu zaÅ”titu prilagoditi pandemiji kako bi ta zaÅ”tita bila uÄinkovita i sigurna i za bolesnike i za pružatelje zaÅ”tite.During the COVID-19 pandemic, there fewer examinations and diagnostic and therapeutic procedures were performed in patients with cardiovascular diseases. In several countries, an increase in mortality has been reported in this group of patients, both from COVID-19 and from cardiovascular diseases. It is important to continue to treat these patients and to prevent the unavailability of health care for subjective or objective reasons. Telemedicine can also help us in this, but much of the responsibility remains with the patients themselves to prevent the disease from getting worse through self-monitoring and regular therapy. We can help them by facilitating this task (telephone contacts, fixed drug combinations). It is also important to adapt healthcare to the pandemic in order to make it effective and safe for both patients and caregivers