US Cosmic Visions: New Ideas in Dark Matter 2017: Community Report

This white paper summarizes the workshop "U.S. Cosmic Visions: New Ideas in Dark Matter" held at University of Maryland on March 23-25, 2017.Comment: 102 pages + reference

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. The 'omics' approaches to identifying biomarkers from the host-response to bacterial infection are promising. In this study, lipidomic analysis was carried out with plasma samples obtained from febrile children with confirmed bacterial infection (n = 20) and confirmed viral infection (n = 20). We show for the first time that bacterial and viral infection produces distinct profile in the host lipidome. Some species of glycerophosphoinositol, sphingomyelin, lysophosphatidylcholine and cholesterol sulfate were higher in the confirmed virus infected group, while some species of fatty acids, glycerophosphocholine, glycerophosphoserine, lactosylceramide and bilirubin were lower in the confirmed virus infected group when compared with confirmed bacterial infected group. A combination of three lipids achieved an area under the receiver operating characteristic (ROC) curve of 0.911 (95% CI 0.81 to 0.98). This pilot study demonstrates the potential of metabolic biomarkers to assist clinicians in distinguishing bacterial from viral infection in febrile children, to facilitate effective clinical management and to the limit inappropriate use of antibiotics

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. The 'omics' approaches to identifying biomarkers from the host-response to bacterial infection are promising. In this study, lipidomic analysis was carried out with plasma samples obtained from febrile children with confirmed bacterial infection (n = 20) and confirmed viral infection (n = 20). We show for the first time that bacterial and viral infection produces distinct profile in the host lipidome. Some species of glycerophosphoinositol, sphingomyelin, lysophosphatidylcholine and cholesterol sulfate were higher in the confirmed virus infected group, while some species of fatty acids, glycerophosphocholine, glycerophosphoserine, lactosylceramide and bilirubin were lower in the confirmed virus infected group when compared with confirmed bacterial infected group. A combination of three lipids achieved an area under the receiver operating characteristic (ROC) curve of 0.911 (95% CI 0.81 to 0.98). This pilot study demonstrates the potential of metabolic biomarkers to assist clinicians in distinguishing bacterial from viral infection in febrile children, to facilitate effective clinical management and to the limit inappropriate use of antibiotics

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection ar

Rechtspfleger in Österreich: Berufsbild und Tätigkeitsprofil im Wandel

Gegenwärtig sind rund 690 Rechtspflegerinnen und Rechtspfleger an österreichischen Bezirks- und Landesgerichten mit mehr als drei Viertel aller erstinstanzlichen Geschäftsfälle befasst. Sie fungieren dabei als erste Anlaufstelle für die rechtssuchende Bevölkerung. Dennoch sind die "Richter ohne Roben" oder die "zweite Säule der dritten Gewalt" in der Öffentlichkeit weitgehend unbekannt und kaum Gegenstand der rechtswissenschaftlichen Forschung. Die Arbeit unternimmt es, die Entwicklung des Rechtspflegerwesens in Österreich anhand der übertragenen Aufgaben und der Änderungen des Tätigkeitsprofils vom Ende der Monarchie bis in die Gegenwart darzustellen, die rechtspolitischen Hintergründe herauszuarbeiten und die Realisierung der Zielsetzungen zu evaluieren. Dabei liegt der Fokus auf folgenden Schwerpunkten: - Gerichtsbarkeit und Rechtspflege am Ende des 19. Jahrhunderts - Erste Republik: Von der Gerichtskanzlei zur Geschäftsstelle - Rechtspfleger und Nationalsozialismus - Der österreichische Rechtspfleger in der Zweiten Republik - Verfassungsrechtliche Grundlagen und das Rechtspflegergesetz 1962 - Der Weg zum Rechtspflegergesetz 1985 - Die Entwicklung seit 1985 und die europäische Vernetzung - Zusammenfassung der Ergebnisseeingereicht von Mag. Dr. Karl JarosUniversität Linz, Diplomarbeit, 2017(VLID)215744

Linear Collider Physics Resource Book for Snowmass 2001, 2: Higgs and Supersymmetry Studies

This Resource Book reviews the physics opportunities of a next-generation e+e- linear collider and discusses options for the experimental program. Part 2 reviews the possible experiments on Higgs bosons and supersymmetric particles that can be done at a linear collider.This Resource Book reviews the physics opportunities of a next-generation e+e- linear collider and discusses options for the experimental program. Part 2 reviews the possible experiments on Higgs bosons and supersymmetric particles that can be done at a linear collider