A number of public or industrial buildings next to two water towers

https://commons.lib.jmu.edu/garber11/1110/thumbnail.jp

TNF-α production from whole blood or THP-1 cells after stimulation with new or used metalworking fluid (MWF) measured with ELISA and expressed as relative luminescence units (RLU).

<p>Whole blood sample was incubated during 4% to 1% of new and used MWF or LPS (positive control) diluted in 0.9% NaCl. THP-1 cells were incubated during 24 hours with 0.01% new or used MWF in culture medium. For details see Materials and method. Each bar represents mean ± SD of two experiments.</p

Average indoor air concentrations of MWF generated substances.

<p>Average indoor air concentrations of MWF generated substances.</p

Demographic characteristics and percent workers that experienced health problems related to work, their work characteristics and the environmental characteristics.

<p>All health problems and environmental factors were frequently experienced (defined as at least once a week).</p><p>p<0.05 and</p><p>p<0.01 between directly and indirectly exposed worker.</p

Protein changes in nasal lavage fluid among subjects with airway symptoms compared to subjects without airway symptoms.

<p>Proteins were separated with 2-DE, visualized with silver staining and identified by mass spectrometry. Quantitative data (optical density, OD) represent median, interquartile range and max/min-values for 8 subjects with airway symptoms and 20 subjects without airway symptoms. A nasal lavage fluid 2-DE protein pattern is shown in the upper left corner. The proteins were separated according to size from top to bottom (250-15 kDa) and according to isoelectric point from left to right (3–10). *p≤0.05, **p≤0.005 (Mann-Whitney U test).</p

Symptoms reported by metalworkers exposed to metalworking fluid (271 individuals), metal workers not exposed to metalworking fluid (24 individuals) and non-exposed reference population (4780 individuals).

<p>The figure shows prevalence of experienced symptoms.</p