Lehrvertragsauflösung und Lehrabbrüche vermindern: Das Potenzial der Sozialen arbeit an Berufsfachschulen

Der Einstieg in eine Berufslehre stellt grosse Anforderungen an junge Menschen. Aus vielfältigen Gründen auf der individuellen, betrieblichen und strukturellen Ebene gelingt es nicht allen Jugendlichen, den Übergang von der Sekundarstufe I in die Berufslehre als wichtige Entwicklungsaufgabe auf Anhieb zu meistern. Rund zehn Prozent der Jugendlichen erreichen keinen zertifizierenden Abschlusses auf der Sekundarstufe II. Die grösste Anzahl Jugendlicher, welche aus dem Berufsbildungssystem ausscheiden, werden nach Lehrvertragsauflösungen verzeichnet. Folgt auf eine Lehrvertragsauflösung keine Anschlusslösung, wird von einem Lehrabbruch gesprochen. Ein fehlender nachobligatorischer Abschluss kann ein Armutsrisiko und soziale Exklusion zur Folge haben. Daher wird in der vorliegenden Bachelor-Arbeit der Frage nachgegangen, welchen Beitrag die Soziale Arbeit an Berufsfachschulen bei der Verminderung von Lehrvertragsauflösungen oder Lehrabbrüchen leisten kann. Im bestehenden Unterstützungssystem, hier exemplarisch im Kanton Luzern, zeigen sich Schwächen in der Begleitung von gefährdeten Jugendlichen. Die Autorinnen kommen zum Schluss, dass die Soziale Arbeit an Berufsfachschulen mit ihren Funktionen wie Früherkennung und Prävention sowie dem Grundprinzip der Lebensweltorientierung über reichhaltiges Potenzial verfügt, die Quote der Lehrvertragsauflösungen und Lehrabbrüche in Kooperation mit anderen involvierten Akteurinnen und Akteuren der Berufsbildung weiter zu vermindern. Mit dem ganzheitlichen Ansatz der Sozialen Arbeit in der Berufsfachschule können gefährdete Jugendliche beim Erreichen eines zertifizierenden Abschlusses ihren Bedürfnissen entsprechend begleitet und unterstützt werden

Fifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016

Peer reviewe

Research needs in allergy: an EAACI position paper, in collaboration with EFA

Abstract In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health systems. More disturbingly, its prevalence and impact are on the rise, a development that has been associated with environmental and lifestyle changes accompanying the continuous process of urbanization and globalization. Therefore, there is an urgent need to prioritize and concert research efforts in the field of allergy, in order to achieve sustainable results on prevention, diagnosis and treatment of this most prevalent chronic disease of the 21 st century. The European Academy of Allergy and Clinical Immunology (EAACI) is the leading professional organization in the field of allergy, promoting excellence in clinical care, education, training and basic and translational research, all with the ultimate goal of improving the health of allergic patients. The European Federation of Allergy and Airways Diseases Patients' Associations (EFA) is a non-profit network of allergy, asthma and Chronic Obstructive Pulmonary Disorder (COPD) patients' organizations. In support of their missions, the present EAACI Position Paper, in collaboration with EFA, highlights the most important research needs in the field of allergy to serve as key recommendations for future research funding at the national and European levels. Although allergies may involve almost every organ of the body and an array of diverse external factors act as triggers, there are several common themes that need to be prioritized in research efforts. As in many other chronic diseases, effective prevention, curative treatment and accurate, rapid diagnosis represent major unmet needs. Detailed phenotyping/endotyping stands out as widely required in order to arrange or re-categorize clinical syndromes into more coherent, uniform and treatment-responsive groups. Research efforts to unveil the basic pathophysiologic pathways and mechanisms, thus leading to the comprehension and resolution of the pathophysiologic complexity of allergies will allow for the design of novel patient-oriented diagnostic and treatment protocols. Several allergic diseases require well-controlled epidemiological description and surveillance, using disease registries, pharmacoeconomic evaluation, as well as large biobanks. Additionally, there is a need for extensive studies to bring promising new biotechnological innovations, such as biological agents, vaccines of modified allergen molecules and engineered components for allergy diagnosis, closer to clinical practice. Finally, particular attention should be paid to the difficult-to-manage, precarious and costly severe disease forms and/or exacerbations. Nonetheless, currently arising treatments, mainly in the fields of immunotherapy and biologicals, hold great promise for targeted and causal management of allergic conditions. Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein

Instrumentarium zur Messung der Klientinnen- und Klientenzufriedenheit: Entwicklung von Fragebogen und Auswertungstool zur Selbstevaluation für elbe, Fachstelle für Lebensfragen, Luzern: Projektbericht

Keine Beschreibung

Structure of mitochondrial creatine kinase

CREATINE kinase (CK; EC 2.7.3.2), an enzyme important for energy metabolism in cells of high and fluctuating energy requirements, catalyses the reversible transfer of a phosphoryl goup from phosphocreatine to ADP1–3. We have solved the structure of the octameric mitochondrial isoform, Mib-CK, which is located in the intermembrane compartment and along the cristae membranes. Mib-CK consumes ATP produced in the mitochondria for the production of phosphocreatine, which is then exported into the cytosol for fast regeneration of ATP by the eytosolic CK isoforms. The octamer has 422 point-group symmetry, and appears as a cube of side length 93 Å with a channel 20 Å wide extending along the four-fold axis. Positively charged amino acids at the four-fold faces of the octamer possibly interact with negatively charged mitochondrial membranes. Each monomer consists of a small α-helical domain and a large domain containing an eight-stranded antiparallel β-sheet flanked by seven α-helices. The conserved residues of the CK family form a compact cluster that covers the active site between the domains

Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness

"Flare-up" reactions are late manifestations of severe T-cell-mediated drug hypersensitivity reactions. Management is anti-inflammatory treatment and avoiding unnecessary medicines. Symptoms like fever, lymph node swelling, and blood count abnormalities may lead to confusion with bacterial infections. For prompt recognition it is important to keep the differential diagnosis in mind