ADHD Medication Protocols in the College Setting: A Standardized Student Provider Agreement

Purpose. Stimulant medication use and abuse is growing throughout the country, especially on college campuses. Diversion, through selling or giving of stimulant medication among college students is a common practice. Over half of college students currently taking a stimulant for Attention Deficit Hyperactive Disorder (ADHD) report diverting medication to a peer at least once. Reasons for misuse of stimulants include increased academic performance, increased attention, weight loss, and increased motivation. A standardized student provider agreement was needed for the student population at a small private college health center given a lack of clear expectations for the use of stimulants for ADHD treatment therapy. The nurse practitioners (NPs) of this college health center identified the need for a new agreement, and also identified the need for an educational session for providers to discuss current diversion statistics and best practice for reducing diversion of stimulant medications. Methods. A closed question pre-test survey was administered to health center NPs to assess knowledge and comfort level in addressing stimulant medication diversion. The current best practice components of existing student provider agreements were reviewed, followed by a post-test survey. Based on discussion during the educational intervention, NP preferences were incorporated into a drafted student-provider agreement followed by iterative refinement of the agreement by the NPs. Results. The educational session was held with 100% attendance from NPs. All pretest and posttests were completed, with results demonstrating increased comfort and knowledge regarding best practice. Over the course of one semester, a student-provider stimulant therapy agreement was successfully developed. Conclusion. The education session resulted in improved participation in best practice guideline changes. The student provider agreement was approved by health center NPs and will be implemented in the fall 2018 academic year

Genetics of Isolated Hypogonadotropic Hypogonadism: Role of GnRH Receptor and Other Genes

Hypothalamic gonadotropin releasing hormone (GnRH) is a key player in normal puberty and sexual development and function. Genetic causes of isolated hypogonadotropic hypogonadism (IHH) have been identified during the recent years affecting the synthesis, secretion, or action of GnRH. Developmental defects of GnRH neurons and the olfactory bulb are associated with hyposmia, rarely associated with the clinical phenotypes of synkinesia, cleft palate, ear anomalies, or choanal atresia, and may be due to mutations of KAL1, FGFR1/FGF8, PROKR2/PROK2, or CHD7. Impaired GnRH secretion in normosmic patients with IHH may be caused by deficient hypothalamic GPR54/KISS1, TACR3/TAC3, and leptinR/leptin signalling or mutations within the GNRH1 gene itself. Normosmic IHH is predominantly caused by inactivating mutations in the pituitary GnRH receptor inducing GnRH resistance, while mutations of the β-subunits of LH or FSH are very rare. Inheritance of GnRH deficiency may be oligogenic, explaining variable phenotypes. Future research should identify additional genes involved in the complex network of normal and disturbed puberty and reproduction

Tour the World Club

This Tour the World club gives students the opportunity to interact with the world, other cultures, and people groups. Through six or seven different countries and many hands-on activities, students will learn what it means to keep an open mind, they will develop a curiosity for the world, and they will be encouraged to prioritize learning and asking questions over giving judgments when faced with something new

Farancia abacura

Number of Pages: 2Integrative BiologyGeological Science

Metal Dipyrrin Complexes as Potential Photosensitizers for Photodynamic Therapy

International audienceOver the last decades, the use of photodynamic therapy (PDT) for the treatment of various types of cancer as well fungal, viral and bacterial infections has received increasing attention. Despite its clinical success, the currently approved photosensitizers (PSs) are associated with poor water solubility, aggregation, low photostability and a long excretion time. To overcome these limitations, much research is devoted towards the development of PSs based on transition metal complexes. However, the majority of metals used for this purpose are rare and expensive. Therefore, it would be of high interest to develop effective PDT PSs based on cheap and abundant metals. In this article, the use of Cu(II) and Ni(II) dipyrrin complexes as potential PDT PSs against cancer is presented. As required for PDT applications, these complexes were found to have a strong absorption in the green spectrum and to be stable in an aqueous solution in the dark as well as upon light irradiation. Biological studies revealed that the complexes have a very low cytotoxic effect in the dark with a slight effect upon irradiation at 510 nm in human cervical carcinoma (HeLa) cells

Iodine Monochloride

Iodine monochloride may be prepared in quantity and of superior quality by the reaction between solid iodine and liquid chlorine at -78°: Vapor pressure measurement of iodine monochloride between 30° and 60° indicate that it is a polar substance. If Ammonium chloride or potassium chloride is dissolved in liquid iodine monochloride conducting solutions are formed. When iodine monochloride reacts with common salts and chemical reaction ensues the reaction is usually either direct addition or else is solvolytic

Kurzversion des Berichts zum Projekt Vorbereitung Lehrmittelobligatorium Clin d’oeil und New World in Solothurner Sek-P-Klassen: Wissenschaftliche Begleitung und Auswertung der Testphase: Durchgeführt vom 15. August 2015 bis 31. Dezember 2017 am Institut für Mehrsprachigkeit der Universität Freiburg und der Pädagogischen Hochschule Freiburg im Auftrag des Kantons Solothurn, Departement für Bildung und Kultur (DBK)

Ab dem Schuljahr 2018/2019 sollen die Schülerinnen und Schüler der Sek P im Kanton Solothurn Französisch und Englisch obligatorisch mit den neuen, im Rahmen der Projektumsetzung von Passepartout entwickelten Lehrwerken Clin d’oeil und New World lernen. Im Auftrag des Kantons Solothurn, Departement für Bildung und Kultur (DBK) hat das Institut für Mehrsprachigkeit (IFM) die Pilotphase der beiden Lehrwerke im Rahmen der Vorbereitung des Lehrmittelobligatoriums in den Schuljahren 2015/2016 und 2016/2017 wissenschaftlich begleitet. Während der Testphase der neuen Lehrmittel wurden je fünf Französisch- und Englischklassen (Pilotklassen) mit Clin d’oeil bzw. New World unterrichtet. Alle übrigen Sek-P-Klassen arbeiteten während dieser Zeit mit den bisherigen Lehrwerken Découvertes (Französisch) und Snapshot bzw. Swift (Englisch). An der vorliegenden Studie nahmen alle Lehrpersonen und Lernenden der Pilotklassen teil, sowie Unterrichtende und Lernende von je fünf weiteren Französisch- und Englischklassen (Vergleichsklassen), die mit bisherigen Lehrwerken arbeiteten